SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mmh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXV_B_PNNB1001_0
(PENICILLIN ACYLASE)		 4mmh HEPARINASE III
PROTEIN
(Pedobacter
heparinus) 		4 / 7 PHE A 256
SER A 262
SER A 223
PHE A 220
 None
 1.23A 1fxvA-4mmhA:
undetectable
1fxvB-4mmhA:
2.1		 1fxvA-4mmhA:
18.30
1fxvB-4mmhA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 4mmh HEPARINASE III
PROTEIN
(Pedobacter
heparinus) 		4 / 5 TYR A 306
TYR A 322
ILE A 270
GLY A 307
 None
 1.18A 1kifA-4mmhA:
undetectable		 1kifA-4mmhA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 4mmh HEPARINASE III
PROTEIN
(Pedobacter
heparinus) 		4 / 5 TYR A 306
TYR A 322
ILE A 270
GLY A 307
 None
 1.18A 1kifB-4mmhA:
undetectable		 1kifB-4mmhA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 4mmh HEPARINASE III
PROTEIN
(Pedobacter
heparinus) 		4 / 5 TYR A 306
TYR A 322
ILE A 270
GLY A 307
 None
 1.18A 1kifC-4mmhA:
undetectable		 1kifC-4mmhA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 4mmh HEPARINASE III
PROTEIN
(Pedobacter
heparinus) 		4 / 5 TYR A 306
TYR A 322
ILE A 270
GLY A 307
 None
 1.18A 1kifD-4mmhA:
undetectable		 1kifD-4mmhA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 4mmh HEPARINASE III
PROTEIN
(Pedobacter
heparinus) 		4 / 5 TYR A 306
TYR A 322
ILE A 270
GLY A 307
 None
 1.18A 1kifE-4mmhA:
undetectable		 1kifE-4mmhA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 4mmh HEPARINASE III
PROTEIN
(Pedobacter
heparinus) 		4 / 5 TYR A 306
TYR A 322
ILE A 270
GLY A 307
 None
 1.18A 1kifF-4mmhA:
undetectable		 1kifF-4mmhA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 4mmh HEPARINASE III
PROTEIN
(Pedobacter
heparinus) 		4 / 5 TYR A 306
TYR A 322
ILE A 270
GLY A 307
 None
 1.18A 1kifG-4mmhA:
undetectable		 1kifG-4mmhA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 4mmh HEPARINASE III
PROTEIN
(Pedobacter
heparinus) 		4 / 5 TYR A 306
TYR A 322
ILE A 270
GLY A 307
 None
 1.18A 1kifH-4mmhA:
undetectable		 1kifH-4mmhA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 4mmh HEPARINASE III
PROTEIN
(Pedobacter
heparinus) 		4 / 5 TYR A 306
TYR A 322
ILE A 270
GLY A 307
 None
 1.18A 1ve9A-4mmhA:
undetectable		 1ve9A-4mmhA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 4mmh HEPARINASE III
PROTEIN
(Pedobacter
heparinus) 		3 / 3 GLY A 641
GLU A 661
ASP A 637
 None
 0.56A 2b25B-4mmhA:
undetectable		 2b25B-4mmhA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 4mmh HEPARINASE III
PROTEIN
(Pedobacter
heparinus) 		4 / 5 TYR A 306
TYR A 322
ILE A 270
GLY A 307
 None
 1.12A 2du8G-4mmhA:
undetectable		 2du8G-4mmhA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 4mmh HEPARINASE III
PROTEIN
(Pedobacter
heparinus) 		4 / 5 TYR A 306
TYR A 322
ILE A 270
GLY A 307
 None
 1.16A 2du8J-4mmhA:
undetectable		 2du8J-4mmhA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA502_0
(CHORISMATE SYNTHASE)		 4mmh HEPARINASE III
PROTEIN
(Pedobacter
heparinus) 		3 / 3 GLY A 347
ASP A 348
SER A 291
 CA  A 702 ( 4.6A)
None
None
 0.69A 2qhfA-4mmhA:
undetectable		 2qhfA-4mmhA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4mmh HEPARINASE III
PROTEIN
(Pedobacter
heparinus) 		5 / 12 LEU A 643
VAL A 656
THR A 499
SER A 395
PHE A 402
 None
 1.48A 2y00B-4mmhA:
undetectable		 2y00B-4mmhA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CO4_A_GCSA401_1
(CHITINASE)		 4mmh HEPARINASE III
PROTEIN
(Pedobacter
heparinus) 		3 / 3 GLU A 490
HIS A 663
HIS A 664
 None
 0.94A 3co4A-4mmhA:
undetectable		 3co4A-4mmhA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EJ8_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4mmh HEPARINASE III
PROTEIN
(Pedobacter
heparinus) 		4 / 7 TRP A 364
PHE A 361
MET A 331
ILE A 299
 None
 1.49A 3ej8A-4mmhA:
undetectable
3ej8B-4mmhA:
undetectable		 3ej8A-4mmhA:
21.10
3ej8B-4mmhA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EJ8_C_H4BC3902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4mmh HEPARINASE III
PROTEIN
(Pedobacter
heparinus) 		4 / 7 MET A 331
ILE A 299
TRP A 364
PHE A 361
 None
 1.45A 3ej8C-4mmhA:
undetectable
3ej8D-4mmhA:
undetectable		 3ej8C-4mmhA:
21.10
3ej8D-4mmhA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		 4mmh HEPARINASE III
PROTEIN
(Pedobacter
heparinus) 		3 / 3 PHE A 435
TYR A 341
LEU A 415
 None
 0.68A 3keeB-4mmhA:
undetectable		 3keeB-4mmhA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHN_A_ACTA108_0
(PROTEIN P-30)		 4mmh HEPARINASE III
PROTEIN
(Pedobacter
heparinus) 		3 / 3 THR A 401
SER A 391
ARG A 403
 None
 0.82A 3phnA-4mmhA:
undetectable		 3phnA-4mmhA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5P_A_TACA7101_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 4mmh HEPARINASE III
PROTEIN
(Pedobacter
heparinus) 		5 / 12 PRO A 443
ASN A 565
TYR A 561
TYR A 588
GLU A 544
 None
 1.38A 3q5pA-4mmhA:
undetectable		 3q5pA-4mmhA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5R_A_KANA2002_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 4mmh HEPARINASE III
PROTEIN
(Pedobacter
heparinus) 		5 / 11 PRO A 443
ASN A 565
TYR A 561
TYR A 588
GLU A 544
 None
 1.47A 3q5rA-4mmhA:
undetectable		 3q5rA-4mmhA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		 4mmh HEPARINASE III
PROTEIN
(Pedobacter
heparinus) 		3 / 3 ASP A 284
GLY A 398
TYR A 282
 None
 0.69A 3w9tC-4mmhA:
undetectable		 3w9tC-4mmhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		 4mmh HEPARINASE III
PROTEIN
(Pedobacter
heparinus) 		3 / 3 ASP A 284
GLY A 398
TYR A 282
 None
 0.69A 3w9tG-4mmhA:
undetectable		 3w9tG-4mmhA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4mmh HEPARINASE III
PROTEIN
(Pedobacter
heparinus) 		5 / 12 PHE A 356
LEU A 333
ILE A 299
ALA A 362
SER A 363
 None
 1.39A 4a83A-4mmhA:
undetectable		 4a83A-4mmhA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4mmh HEPARINASE III
PROTEIN
(Pedobacter
heparinus) 		4 / 6 ASP A 428
ALA A 417
THR A 431
THR A 471
 None
 1.44A 4w5qA-4mmhA:
undetectable		 4w5qA-4mmhA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 4mmh HEPARINASE III
PROTEIN
(Pedobacter
heparinus) 		3 / 3 LYS A 603
PRO A 604
LYS A 606
 None
 1.19A 5y9yA-4mmhA:
undetectable		 5y9yA-4mmhA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_B_TRPB403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)		 4mmh HEPARINASE III
PROTEIN
(Pedobacter
heparinus) 		4 / 7 GLU A 544
THR A 442
PRO A 443
PRO A 597
 None
 1.28A 6a4iB-4mmhA:
undetectable		 6a4iB-4mmhA:
20.59