SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mmq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_GLYA1292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4mmq FUSION GLYCOPROTEIN
F1 FUSED WITH
FIBRITIN
TRIMERIZATION DOMAIN
(Escherichia
virus
T4;
Human
orthopneumovirus) 		4 / 8 SER B 287
SER B 248
TYR B 299
PHE B 237
 None
 1.20A 1eqbA-4mmqB:
undetectable
1eqbB-4mmqB:
undetectable		 1eqbA-4mmqB:
21.52
1eqbB-4mmqB:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_GLYB2292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4mmq FUSION GLYCOPROTEIN
F1 FUSED WITH
FIBRITIN
TRIMERIZATION DOMAIN
(Escherichia
virus
T4;
Human
orthopneumovirus) 		4 / 8 TYR B 299
PHE B 237
SER B 287
SER B 248
 None
 1.23A 1eqbA-4mmqB:
undetectable
1eqbB-4mmqB:
undetectable		 1eqbA-4mmqB:
21.52
1eqbB-4mmqB:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_GLYC3292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4mmq FUSION GLYCOPROTEIN
F1 FUSED WITH
FIBRITIN
TRIMERIZATION DOMAIN
(Escherichia
virus
T4;
Human
orthopneumovirus) 		4 / 8 SER B 287
SER B 248
TYR B 299
PHE B 237
 None
 1.21A 1eqbC-4mmqB:
undetectable
1eqbD-4mmqB:
undetectable		 1eqbC-4mmqB:
21.52
1eqbD-4mmqB:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_GLYD4292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4mmq FUSION GLYCOPROTEIN
F1 FUSED WITH
FIBRITIN
TRIMERIZATION DOMAIN
(Escherichia
virus
T4;
Human
orthopneumovirus) 		4 / 8 TYR B 299
PHE B 237
SER B 287
SER B 248
 None
 1.23A 1eqbC-4mmqB:
undetectable
1eqbD-4mmqB:
undetectable		 1eqbC-4mmqB:
21.52
1eqbD-4mmqB:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDY_A_RBFA187_1
(LUMAZINE PROTEIN)		 4mmq FUSION GLYCOPROTEIN
F1 FUSED WITH
FIBRITIN
TRIMERIZATION DOMAIN
(Escherichia
virus
T4;
Human
orthopneumovirus) 		5 / 12 SER B 493
ASN B 496
ILE B 499
THR B 397
ILE B 395
 None
 1.24A 3ddyA-4mmqB:
undetectable		 3ddyA-4mmqB:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_B_BEZB301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 4mmq FUSION GLYCOPROTEIN
F1 FUSED WITH
FIBRITIN
TRIMERIZATION DOMAIN
(Escherichia
virus
T4;
Human
orthopneumovirus) 		4 / 8 ILE B 261
LEU B 257
LEU B 252
PRO B 304
 None
 0.81A 5u4sB-4mmqB:
undetectable		 5u4sB-4mmqB:
19.04