SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mn7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_B_VIBB501_1
(THIAMIN
PYROPHOSPHOKINASE)		 4mn7 PUTATIVE
UNCHARACTERIZED
PROTEIN TA0848
(Thermoplasma
acidophilum) 		4 / 7 GLN A  89
ASP A  74
LEU A  59
SER A 110
 None
 1.23A 1ig3A-4mn7A:
undetectable
1ig3B-4mn7A:
undetectable		 1ig3A-4mn7A:
20.31
1ig3B-4mn7A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJO_A_CUA701_0
(PHENYLETHYLAMINE
OXIDASE)		 4mn7 PUTATIVE
UNCHARACTERIZED
PROTEIN TA0848
(Thermoplasma
acidophilum) 		3 / 3 HIS A 146
HIS A 147
HIS A 144
 None
 0.68A 1rjoA-4mn7A:
undetectable		 1rjoA-4mn7A:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RKY_A_CUA801_0
(LYSYL OXIDASE)		 4mn7 PUTATIVE
UNCHARACTERIZED
PROTEIN TA0848
(Thermoplasma
acidophilum) 		3 / 3 HIS A 146
HIS A 147
HIS A 144
 None
 0.58A 1rkyA-4mn7A:
undetectable		 1rkyA-4mn7A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_B_CUB701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 4mn7 PUTATIVE
UNCHARACTERIZED
PROTEIN TA0848
(Thermoplasma
acidophilum) 		3 / 3 HIS A 146
HIS A 147
HIS A 144
 None
 0.71A 1w2zB-4mn7A:
undetectable		 1w2zB-4mn7A:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_C_CUC701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 4mn7 PUTATIVE
UNCHARACTERIZED
PROTEIN TA0848
(Thermoplasma
acidophilum) 		3 / 3 HIS A 146
HIS A 147
HIS A 144
 None
 0.70A 1w2zC-4mn7A:
undetectable		 1w2zC-4mn7A:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_D_CUD701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 4mn7 PUTATIVE
UNCHARACTERIZED
PROTEIN TA0848
(Thermoplasma
acidophilum) 		3 / 3 HIS A 146
HIS A 147
HIS A 144
 None
 0.68A 1w2zD-4mn7A:
undetectable		 1w2zD-4mn7A:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4mn7 PUTATIVE
UNCHARACTERIZED
PROTEIN TA0848
(Thermoplasma
acidophilum) 		3 / 3 HIS A 146
HIS A 147
HIS A 144
 None
 0.70A 2oqeA-4mn7A:
undetectable		 2oqeA-4mn7A:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4mn7 PUTATIVE
UNCHARACTERIZED
PROTEIN TA0848
(Thermoplasma
acidophilum) 		3 / 3 HIS A 146
HIS A 147
HIS A 144
 None
 0.71A 2oqeB-4mn7A:
undetectable		 2oqeB-4mn7A:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_C_CUC801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4mn7 PUTATIVE
UNCHARACTERIZED
PROTEIN TA0848
(Thermoplasma
acidophilum) 		3 / 3 HIS A 146
HIS A 147
HIS A 144
 None
 0.68A 2oqeC-4mn7A:
undetectable		 2oqeC-4mn7A:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4mn7 PUTATIVE
UNCHARACTERIZED
PROTEIN TA0848
(Thermoplasma
acidophilum) 		3 / 3 HIS A 146
HIS A 147
HIS A 144
 None
 0.69A 2oqeD-4mn7A:
undetectable		 2oqeD-4mn7A:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4mn7 PUTATIVE
UNCHARACTERIZED
PROTEIN TA0848
(Thermoplasma
acidophilum) 		3 / 3 HIS A 146
HIS A 147
HIS A 144
 None
 0.70A 2oqeF-4mn7A:
undetectable		 2oqeF-4mn7A:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 4mn7 PUTATIVE
UNCHARACTERIZED
PROTEIN TA0848
(Thermoplasma
acidophilum) 		5 / 12 LEU A  18
ILE A 108
ALA A 115
PHE A 116
ASP A  26
 None
 1.11A 2qb4A-4mn7A:
undetectable		 2qb4A-4mn7A:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBO_A_CAMA442_0
(CYTOCHROME P450-CAM)		 4mn7 PUTATIVE
UNCHARACTERIZED
PROTEIN TA0848
(Thermoplasma
acidophilum) 		5 / 10 PHE A 116
VAL A  28
ASP A 120
ILE A  92
VAL A  94
 None
 1.50A 2qboA-4mn7A:
undetectable		 2qboA-4mn7A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QJU_A_DSMA801_1
(TRANSPORTER)		 4mn7 PUTATIVE
UNCHARACTERIZED
PROTEIN TA0848
(Thermoplasma
acidophilum) 		5 / 11 LEU A  18
ILE A 108
ALA A 115
PHE A 116
ASP A  26
 None
 1.16A 2qjuA-4mn7A:
0.8		 2qjuA-4mn7A:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_A_CUA801_0
(COPPER AMINE OXIDASE)		 4mn7 PUTATIVE
UNCHARACTERIZED
PROTEIN TA0848
(Thermoplasma
acidophilum) 		3 / 3 HIS A 146
HIS A 147
HIS A 144
 None
 0.64A 2w0qA-4mn7A:
undetectable		 2w0qA-4mn7A:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_B_CUB801_0
(COPPER AMINE OXIDASE)		 4mn7 PUTATIVE
UNCHARACTERIZED
PROTEIN TA0848
(Thermoplasma
acidophilum) 		3 / 3 HIS A 146
HIS A 147
HIS A 144
 None
 0.68A 2w0qB-4mn7A:
undetectable		 2w0qB-4mn7A:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4mn7 PUTATIVE
UNCHARACTERIZED
PROTEIN TA0848
(Thermoplasma
acidophilum) 		3 / 3 HIS A 144
HIS A 146
HIS A 147
 None
 0.74A 3ag4A-4mn7A:
undetectable		 3ag4A-4mn7A:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4mn7 PUTATIVE
UNCHARACTERIZED
PROTEIN TA0848
(Thermoplasma
acidophilum) 		3 / 3 HIS A 144
HIS A 146
HIS A 147
 None
 0.76A 3ag4N-4mn7A:
undetectable		 3ag4N-4mn7A:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_A_CUA801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 4mn7 PUTATIVE
UNCHARACTERIZED
PROTEIN TA0848
(Thermoplasma
acidophilum) 		3 / 3 HIS A 146
HIS A 147
HIS A 144
 None
 0.67A 3hiiA-4mn7A:
undetectable		 3hiiA-4mn7A:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_B_CUB801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 4mn7 PUTATIVE
UNCHARACTERIZED
PROTEIN TA0848
(Thermoplasma
acidophilum) 		3 / 3 HIS A 146
HIS A 147
HIS A 144
 None
 0.65A 3hiiB-4mn7A:
undetectable		 3hiiB-4mn7A:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		 4mn7 PUTATIVE
UNCHARACTERIZED
PROTEIN TA0848
(Thermoplasma
acidophilum) 		4 / 7 VAL A  94
LEU A  18
ASN A  22
ILE A 127
 None
 0.89A 3rfmA-4mn7A:
undetectable		 3rfmA-4mn7A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTH_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 4mn7 PUTATIVE
UNCHARACTERIZED
PROTEIN TA0848
(Thermoplasma
acidophilum) 		3 / 3 ASP A   2
LEU A   3
PHE A   6
 None
 0.62A 4pthA-4mn7A:
undetectable		 4pthA-4mn7A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4mn7 PUTATIVE
UNCHARACTERIZED
PROTEIN TA0848
(Thermoplasma
acidophilum) 		3 / 3 HIS A 144
HIS A 146
HIS A 147
 None
 0.75A 5b3sN-4mn7A:
undetectable		 5b3sN-4mn7A:
12.25