SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mng'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OLD_B_IPHB2001_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 4mng TRA@ PROTEIN,TRA@
PROTEIN, TI ANTIGEN
CD3-ASSOCIATED
PROTEIN GAMMA CHAIN
V-J-C REGION
(Homo
sapiens) 		4 / 7 TYR E 175
HIS E 177
PRO E 183
TYR E 233
 None
 0.60A 2oldA-4mngE:
13.7
2oldB-4mngE:
13.6		 2oldA-4mngE:
24.16
2oldB-4mngE:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_A_IPHA2001_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 4mng TRA@ PROTEIN,TRA@
PROTEIN, TI ANTIGEN
CD3-ASSOCIATED
PROTEIN GAMMA CHAIN
V-J-C REGION
(Homo
sapiens) 		4 / 5 HIS E 177
PRO E 183
TYR E 233
TYR E  37
 None
 1.12A 2ombA-4mngE:
13.7
2ombB-4mngE:
13.5		 2ombA-4mngE:
24.16
2ombB-4mngE:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 4mng TRA@ PROTEIN,TRA@
PROTEIN, TI ANTIGEN
CD3-ASSOCIATED
PROTEIN GAMMA CHAIN
V-J-C REGION
(Homo
sapiens) 		4 / 7 TYR E  37
HIS E 177
PRO E 183
TYR E 233
 None
 0.89A 2ombC-4mngE:
13.4
2ombD-4mngE:
13.5		 2ombC-4mngE:
24.16
2ombD-4mngE:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 4mng TRA@ PROTEIN,TRA@
PROTEIN, TI ANTIGEN
CD3-ASSOCIATED
PROTEIN GAMMA CHAIN
V-J-C REGION
(Homo
sapiens) 		4 / 7 TYR E 175
HIS E 177
PRO E 183
TYR E 233
 None
 0.57A 2ombC-4mngE:
13.4
2ombD-4mngE:
13.5		 2ombC-4mngE:
24.16
2ombD-4mngE:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTF_A_2TNA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 4mng TRA@ PROTEIN,TRA@
PROTEIN, TI ANTIGEN
CD3-ASSOCIATED
PROTEIN GAMMA CHAIN
V-J-C REGION
(Homo
sapiens) 		4 / 5 LEU E 221
ILE E 254
SER E 229
GLY E 230
 None
 0.83A 2otfA-4mngE:
undetectable		 2otfA-4mngE:
15.75