SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mnm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_A_NCAA700_0
(EXOTOXIN A)		 4mnm CHITINASE A
(Cycas
revoluta) 		4 / 7 GLY A 110
TYR A  32
LEU A 105
TYR A 109
 None
 0.87A 1dmaA-4mnmA:
undetectable		 1dmaA-4mnmA:
23.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 4mnm CHITINASE A
(Cycas
revoluta) 		7 / 9 PHE A  34
GLY A  76
ASP A 117
GLN A 119
MET A 189
ASP A 192
TRP A 327
 None
 0.95A 1e9lA-4mnmA:
45.0		 1e9lA-4mnmA:
31.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 4mnm CHITINASE A
(Cycas
revoluta) 		7 / 9 PHE A  34
GLY A  76
ASP A 117
GLN A 119
MET A 189
TYR A 191
ASP A 192
 None
 0.81A 1e9lA-4mnmA:
45.0		 1e9lA-4mnmA:
31.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPO_H_TESH1010_1
(ANTI-TESTOSTERONE
(HEAVY CHAIN)
ANTI-TESTOSTERONE
(LIGHT CHAIN))		 4mnm CHITINASE A
(Cycas
revoluta) 		5 / 12 SER A 102
ALA A  35
GLY A  75
LEU A  37
PHE A  85
 None
None
SO4  A 404 ( 4.8A)
SO4  A 404 (-4.0A)
None
 1.21A 1vpoH-4mnmA:
undetectable
1vpoL-4mnmA:
undetectable		 1vpoH-4mnmA:
22.35
1vpoL-4mnmA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 4mnm CHITINASE A
(Cycas
revoluta) 		7 / 11 PHE A  34
GLY A  76
ASP A 117
MET A 189
TYR A 191
ASP A 192
TRP A 327
 None
 0.84A 2a3aA-4mnmA:
40.9		 2a3aA-4mnmA:
28.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2433_1
(CHITINASE)		 4mnm CHITINASE A
(Cycas
revoluta) 		6 / 9 PHE A  34
GLY A  76
MET A 189
TYR A 191
ASP A 192
TRP A 327
 None
 0.50A 2a3aB-4mnmA:
41.0		 2a3aB-4mnmA:
28.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 4mnm CHITINASE A
(Cycas
revoluta) 		7 / 11 PHE A  34
GLY A  76
ASP A 117
MET A 189
TYR A 191
ASP A 192
TRP A 327
 None
 0.88A 2a3bA-4mnmA:
40.9		 2a3bA-4mnmA:
28.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 4mnm CHITINASE A
(Cycas
revoluta) 		7 / 10 PHE A  34
GLY A  76
ASP A 117
MET A 189
TYR A 191
ASP A 192
TRP A 327
 None
 0.84A 2a3bB-4mnmA:
41.0		 2a3bB-4mnmA:
28.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 4mnm CHITINASE A
(Cycas
revoluta) 		7 / 12 PHE A  34
GLY A  76
ASP A 117
MET A 189
TYR A 191
ASP A 192
TRP A 327
 None
 0.90A 2a3cA-4mnmA:
40.8		 2a3cA-4mnmA:
28.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 4mnm CHITINASE A
(Cycas
revoluta) 		7 / 12 PHE A  34
GLY A  76
ASP A 117
MET A 189
TYR A 191
ASP A 192
TRP A 327
 None
 0.88A 2a3cB-4mnmA:
41.0		 2a3cB-4mnmA:
28.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_A_SAMA500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 4mnm CHITINASE A
(Cycas
revoluta) 		5 / 11 GLU A  36
ALA A  35
PRO A  48
ALA A  54
ASP A 115
 None
 1.26A 2admA-4mnmA:
undetectable		 2admA-4mnmA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FR3_A_REAA300_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
2)		 4mnm CHITINASE A
(Cycas
revoluta) 		5 / 12 PHE A 326
LEU A 239
ILE A 336
ALA A 341
LEU A 235
 None
 1.06A 2fr3A-4mnmA:
undetectable		 2fr3A-4mnmA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4mnm CHITINASE A
(Cycas
revoluta) 		5 / 12 GLN A 119
PHE A 326
LEU A 239
ALA A 158
VAL A   6
 None
 1.28A 2g70A-4mnmA:
undetectable		 2g70A-4mnmA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4mnm CHITINASE A
(Cycas
revoluta) 		5 / 12 GLN A 119
PHE A 326
LEU A 239
ALA A 158
VAL A   6
 None
 1.39A 2g70B-4mnmA:
undetectable		 2g70B-4mnmA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 4mnm CHITINASE A
(Cycas
revoluta) 		5 / 9 PHE A  34
GLY A  76
ASP A 117
TYR A 191
TRP A 327
 None
 0.33A 2uy4A-4mnmA:
18.3		 2uy4A-4mnmA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 4mnm CHITINASE A
(Cycas
revoluta) 		5 / 11 PHE A  34
GLY A  76
ASP A 117
TYR A 191
TRP A 327
 None
 0.50A 2xtkA-4mnmA:
19.5		 2xtkA-4mnmA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 4mnm CHITINASE A
(Cycas
revoluta) 		5 / 10 PHE A  34
GLY A  76
ASP A 117
TYR A 191
TRP A 327
 None
 0.44A 2xtkB-4mnmA:
19.8		 2xtkB-4mnmA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI9_X_SAMX501_0
(UPF0217 PROTEIN
MJ1640)		 4mnm CHITINASE A
(Cycas
revoluta) 		5 / 9 LEU A 116
ILE A  74
GLY A  75
LEU A 155
LEU A  71
 None
None
SO4  A 404 ( 4.8A)
None
None
 1.04A 3ai9X-4mnmA:
undetectable		 3ai9X-4mnmA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 4mnm CHITINASE A
(Cycas
revoluta) 		7 / 11 PHE A  34
GLY A  76
ASP A 117
MET A 189
TYR A 191
ASP A 192
TRP A 327
 None
 0.88A 3g6mA-4mnmA:
40.9		 3g6mA-4mnmA:
25.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA427_1
(CHITINASE)		 4mnm CHITINASE A
(Cycas
revoluta) 		4 / 5 TYR A 120
MET A 189
ASP A 192
TRP A 197
 None
None
None
NAG  A 402 (-3.6A)
 0.55A 3g6mA-4mnmA:
40.8		 3g6mA-4mnmA:
25.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_B_1N1B2000_1
(P38A)		 4mnm CHITINASE A
(Cycas
revoluta) 		5 / 10 ILE A 237
ILE A 273
ILE A 277
ASN A 305
VAL A 309
 None
 1.43A 3ohtA-4mnmA:
undetectable
3ohtB-4mnmA:
undetectable		 3ohtA-4mnmA:
22.57
3ohtB-4mnmA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 4mnm CHITINASE A
(Cycas
revoluta) 		5 / 12 GLU A  16
PHE A 270
ASP A 334
ILE A 333
ASN A 275
 None
 1.38A 3ps9A-4mnmA:
undetectable		 3ps9A-4mnmA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 4mnm CHITINASE A
(Cycas
revoluta) 		8 / 11 PHE A  34
GLY A  76
ASP A 117
MET A 189
TYR A 191
ASP A 192
ARG A 242
TRP A 327
 None
 0.44A 3wqvA-4mnmA:
43.8		 3wqvA-4mnmA:
29.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 4mnm CHITINASE A
(Cycas
revoluta) 		8 / 11 PHE A  34
GLY A  76
ASP A 117
MET A 189
TYR A 191
ASP A 192
ARG A 242
TRP A 327
 None
 0.48A 3wqwA-4mnmA:
43.9		 3wqwA-4mnmA:
29.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMM_A_CHDA503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4mnm CHITINASE A
(Cycas
revoluta) 		4 / 7 PRO A  10
SER A 328
VAL A  14
TRP A   9
 None
 1.28A 4kmmA-4mnmA:
undetectable		 4kmmA-4mnmA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1X_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 4mnm CHITINASE A
(Cycas
revoluta) 		4 / 8 LEU A  37
VAL A  81
LEU A 137
LEU A 133
 SO4  A 404 (-4.0A)
SO4  A 404 (-3.7A)
None
None
 0.89A 4l1xA-4mnmA:
9.5		 4l1xA-4mnmA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA503_1
(PENTALENIC ACID
SYNTHASE)		 4mnm CHITINASE A
(Cycas
revoluta) 		4 / 7 LEU A 137
ALA A 106
LEU A 153
ILE A  72
 None
 0.81A 4ubsA-4mnmA:
undetectable		 4ubsA-4mnmA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 4mnm CHITINASE A
(Cycas
revoluta) 		3 / 3 VAL A 188
ALA A 158
PHE A 325
 None
 0.75A 4z4iA-4mnmA:
undetectable		 4z4iA-4mnmA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 4mnm CHITINASE A
(Cycas
revoluta) 		6 / 8 PHE A  34
GLY A  76
TYR A 191
ASP A 192
ARG A 242
TRP A 327
 None
 0.66A 5gqbA-4mnmA:
40.9		 5gqbA-4mnmA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS1_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 4mnm CHITINASE A
(Cycas
revoluta) 		3 / 3 VAL A 188
ALA A 158
PHE A 325
 None
 0.73A 5js1A-4mnmA:
undetectable		 5js1A-4mnmA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		 4mnm CHITINASE A
(Cycas
revoluta) 		4 / 7 PRO A 121
TYR A 174
PHE A  85
SER A  73
 None
 1.25A 5l1fC-4mnmA:
3.4		 5l1fC-4mnmA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4mnm CHITINASE A
(Cycas
revoluta) 		3 / 3 VAL A 188
VAL A 159
GLN A 163
 None
 0.65A 5qgjA-4mnmA:
undetectable		 5qgjA-4mnmA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4mnm CHITINASE A
(Cycas
revoluta) 		3 / 3 VAL A 188
VAL A 159
GLN A 163
 None
 0.62A 5qgmA-4mnmA:
undetectable		 5qgmA-4mnmA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4mnm CHITINASE A
(Cycas
revoluta) 		3 / 3 VAL A 188
VAL A 159
GLN A 163
 None
 0.65A 5qh6A-4mnmA:
undetectable		 5qh6A-4mnmA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4mnm CHITINASE A
(Cycas
revoluta) 		3 / 3 VAL A 188
VAL A 159
GLN A 163
 None
 0.67A 5qhaA-4mnmA:
undetectable		 5qhaA-4mnmA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 4mnm CHITINASE A
(Cycas
revoluta) 		4 / 8 ILE A 179
THR A 172
VAL A 171
GLU A 122
 EDO  A 401 ( 4.8A)
None
None
None
 1.17A 6fbvC-4mnmA:
undetectable		 6fbvC-4mnmA:
15.45