SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mnu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J83_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)
4mnu SLYA-LIKE
TRANSCRIPTION
REGULATOR

(Listeria
monocytogenes)
5 / 11 ILE A 102
GLY A  31
ASN A  20
ASN A 105
GLU A  41
None
1.34A 4j83A-4mnuA:
undetectable
4j83A-4mnuA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_D_SAMD401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)
4mnu SLYA-LIKE
TRANSCRIPTION
REGULATOR

(Listeria
monocytogenes)
5 / 11 ILE A 102
GLY A  31
ASN A  20
ASN A 105
GLU A  41
None
1.44A 4jdsD-4mnuA:
undetectable
4jdsD-4mnuA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLG_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)
4mnu SLYA-LIKE
TRANSCRIPTION
REGULATOR

(Listeria
monocytogenes)
5 / 11 ILE A 102
GLY A  31
ASN A  20
ASN A 105
GLU A  41
None
1.43A 4jlgB-4mnuA:
undetectable
4jlgB-4mnuA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)
4mnu SLYA-LIKE
TRANSCRIPTION
REGULATOR

(Listeria
monocytogenes)
4 / 6 ASN A 105
TYR A 107
GLU A 104
GLU A  22
None
1.15A 4mi4A-4mnuA:
undetectable
4mi4A-4mnuA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)
4mnu SLYA-LIKE
TRANSCRIPTION
REGULATOR

(Listeria
monocytogenes)
4 / 7 ASN A 105
TYR A 107
GLU A 104
GLU A  22
None
1.15A 4mi4B-4mnuA:
undetectable
4mi4C-4mnuA:
undetectable
4mi4B-4mnuA:
24.61
4mi4C-4mnuA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)
4mnu SLYA-LIKE
TRANSCRIPTION
REGULATOR

(Listeria
monocytogenes)
4 / 7 ASN A 105
TYR A 107
GLU A 104
GLU A  22
None
1.12A 4mi4A-4mnuA:
undetectable
4mi4C-4mnuA:
undetectable
4mi4A-4mnuA:
24.61
4mi4C-4mnuA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)
4mnu SLYA-LIKE
TRANSCRIPTION
REGULATOR

(Listeria
monocytogenes)
4 / 8 ASN A 105
TYR A 107
GLU A 104
GLU A  22
None
1.16A 4mj8A-4mnuA:
undetectable
4mj8C-4mnuA:
undetectable
4mj8A-4mnuA:
24.61
4mj8C-4mnuA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)
4mnu SLYA-LIKE
TRANSCRIPTION
REGULATOR

(Listeria
monocytogenes)
4 / 8 ASN A 105
TYR A 107
GLU A 104
GLU A  22
None
1.13A 4mj8B-4mnuA:
undetectable
4mj8C-4mnuA:
undetectable
4mj8B-4mnuA:
24.61
4mj8C-4mnuA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)
4mnu SLYA-LIKE
TRANSCRIPTION
REGULATOR

(Listeria
monocytogenes)
4 / 7 ASN A 105
TYR A 107
GLU A 104
GLU A  22
None
1.15A 4mj8C-4mnuA:
undetectable
4mj8C-4mnuA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_H_SPMH202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)
4mnu SLYA-LIKE
TRANSCRIPTION
REGULATOR

(Listeria
monocytogenes)
4 / 6 ASN A 105
TYR A 107
GLU A 104
GLU A  22
None
1.06A 4r87H-4mnuA:
undetectable
4r87H-4mnuA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_I_SPMI202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)
4mnu SLYA-LIKE
TRANSCRIPTION
REGULATOR

(Listeria
monocytogenes)
4 / 7 ASN A 105
TYR A 107
GLU A 104
GLU A  22
None
1.20A 4r87I-4mnuA:
undetectable
4r87I-4mnuA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA612_0
(NADH DEHYDROGENASE,
PUTATIVE)
4mnu SLYA-LIKE
TRANSCRIPTION
REGULATOR

(Listeria
monocytogenes)
3 / 3 LYS A  49
ASP A  52
ARG A  38
None
None
SO4  A 203 (-2.6A)
0.95A 5jwaA-4mnuA:
undetectable
5jwaH-4mnuA:
undetectable
5jwaA-4mnuA:
15.59
5jwaH-4mnuA:
15.59