SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mo0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IL1_A_SAMA601_0
(METTL3)		 4mo0 PROTEIN TRANSLATION
FACTOR SUI1 HOMOLOG
(Methanocaldococc
us
jannaschii) 		5 / 12 ILE A  27
SER A  49
PHE A  46
ASN A  73
GLY A  45
 None
 1.35A 5il1A-4mo0A:
undetectable		 5il1A-4mo0A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4mo0 PROTEIN TRANSLATION
FACTOR SUI1 HOMOLOG
(Methanocaldococc
us
jannaschii) 		4 / 5 LEU A  53
LYS A  54
ALA A  57
LEU A  60
 None
 0.61A 5vkqA-4mo0A:
undetectable
5vkqD-4mo0A:
undetectable		 5vkqA-4mo0A:
4.80
5vkqD-4mo0A:
4.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4mo0 PROTEIN TRANSLATION
FACTOR SUI1 HOMOLOG
(Methanocaldococc
us
jannaschii) 		4 / 5 LEU A  53
LYS A  54
ALA A  57
LEU A  60
 None
 0.61A 5vkqA-4mo0A:
undetectable
5vkqB-4mo0A:
undetectable		 5vkqA-4mo0A:
4.80
5vkqB-4mo0A:
4.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4mo0 PROTEIN TRANSLATION
FACTOR SUI1 HOMOLOG
(Methanocaldococc
us
jannaschii) 		4 / 5 LEU A  53
LYS A  54
ALA A  57
LEU A  60
 None
 0.60A 5vkqB-4mo0A:
undetectable
5vkqC-4mo0A:
undetectable		 5vkqB-4mo0A:
4.80
5vkqC-4mo0A:
4.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4mo0 PROTEIN TRANSLATION
FACTOR SUI1 HOMOLOG
(Methanocaldococc
us
jannaschii) 		4 / 5 LEU A  53
LYS A  54
ALA A  57
LEU A  60
 None
 0.61A 5vkqC-4mo0A:
undetectable
5vkqD-4mo0A:
undetectable		 5vkqC-4mo0A:
4.80
5vkqD-4mo0A:
4.80