SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mo1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		 4mo1 ANTITERMINATION
PROTEIN Q
(Escherichia
virus
Lambda) 		4 / 7 THR A 113
GLY A 115
GLY A 123
THR A 124
 None
 0.78A 3tajA-4mo1A:
undetectable		 3tajA-4mo1A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_A_PXLA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4mo1 ANTITERMINATION
PROTEIN Q
(Escherichia
virus
Lambda) 		4 / 7 GLY A 123
GLY A 151
VAL A 189
CYH A 147
 None
ZN  A 301 ( 4.8A)
None
ZN  A 301 (-2.3A)
 0.93A 4c5nA-4mo1A:
undetectable		 4c5nA-4mo1A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9A_A_AR3A201_1
(PEPTIDYL-TRNA
HYDROLASE)		 4mo1 ANTITERMINATION
PROTEIN Q
(Escherichia
virus
Lambda) 		4 / 6 ALA A 100
GLN A  97
GLN A  64
ASP A  62
 None
 1.35A 5y9aA-4mo1A:
undetectable		 5y9aA-4mo1A:
16.67