SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mo2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHJ_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 4mo2 UDP-GALACTOPYRANOSE
MUTASE
(Campylobacter
jejuni) 		5 / 12 ILE B 167
LEU B 170
PRO B 171
ILE B 147
THR B 276
 None
 0.92A 1dhjB-4mo2B:
undetectable		 1dhjB-4mo2B:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_1
(POL POLYPROTEIN)		 4mo2 UDP-GALACTOPYRANOSE
MUTASE
(Campylobacter
jejuni) 		5 / 10 LEU B   5
VAL B 206
ILE B  36
GLY B  37
GLY B  10
 None
None
None
None
FDA  B 402 (-3.5A)
 0.99A 1k6cA-4mo2B:
undetectable		 1k6cA-4mo2B:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_A_AICA5001_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 4mo2 UDP-GALACTOPYRANOSE
MUTASE
(Campylobacter
jejuni) 		4 / 8 ARG B 277
TYR B 268
GLN B 261
HIS B  51
 None
 1.31A 1nx9A-4mo2B:
undetectable		 1nx9A-4mo2B:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_B_AICB5002_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 4mo2 UDP-GALACTOPYRANOSE
MUTASE
(Campylobacter
jejuni) 		4 / 8 ARG B 277
TYR B 268
GLN B 261
HIS B  51
 None
 1.30A 1nx9B-4mo2B:
undetectable		 1nx9B-4mo2B:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_C_AICC5003_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 4mo2 UDP-GALACTOPYRANOSE
MUTASE
(Campylobacter
jejuni) 		4 / 8 ARG B 277
TYR B 268
GLN B 261
HIS B  51
 None
 1.31A 1nx9C-4mo2B:
undetectable		 1nx9C-4mo2B:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_D_AICD5004_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 4mo2 UDP-GALACTOPYRANOSE
MUTASE
(Campylobacter
jejuni) 		4 / 8 ARG B 277
TYR B 268
GLN B 261
HIS B  51
 None
 1.31A 1nx9D-4mo2B:
undetectable		 1nx9D-4mo2B:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_1
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 4mo2 UDP-GALACTOPYRANOSE
MUTASE
(Campylobacter
jejuni) 		3 / 3 GLY B  38
GLU B  31
ASN B  39
 FDA  B 402 (-3.2A)
FDA  B 402 (-2.7A)
FDA  B 402 (-4.2A)
 0.65A 1zq9A-4mo2B:
undetectable		 1zq9A-4mo2B:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 4mo2 UDP-GALACTOPYRANOSE
MUTASE
(Campylobacter
jejuni) 		3 / 3 GLY B 149
GLU B 152
ASP B 270
 None
 0.63A 2b25B-4mo2B:
2.8		 2b25B-4mo2B:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PH9_A_GNTA301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4mo2 UDP-GALACTOPYRANOSE
MUTASE
(Campylobacter
jejuni) 		4 / 7 TYR B 238
TYR B 245
TYR B 324
ILE B 232
 None
 1.06A 2ph9A-4mo2B:
undetectable
2ph9B-4mo2B:
undetectable		 2ph9A-4mo2B:
20.00
2ph9B-4mo2B:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_1
(PROTEASE)		 4mo2 UDP-GALACTOPYRANOSE
MUTASE
(Campylobacter
jejuni) 		5 / 12 LEU B   5
VAL B 206
ILE B  36
GLY B  37
GLY B  10
 None
None
None
None
FDA  B 402 (-3.5A)
 1.06A 2r5pA-4mo2B:
undetectable		 2r5pA-4mo2B:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_1
(PROTEASE)		 4mo2 UDP-GALACTOPYRANOSE
MUTASE
(Campylobacter
jejuni) 		5 / 12 LEU B   5
VAL B 206
ILE B  36
GLY B  37
GLY B  10
 None
None
None
None
FDA  B 402 (-3.5A)
 1.06A 2r5pC-4mo2B:
undetectable		 2r5pC-4mo2B:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_CHDA332_0
(CHOLOYLGLYCINE
HYDROLASE)		 4mo2 UDP-GALACTOPYRANOSE
MUTASE
(Campylobacter
jejuni) 		5 / 12 ILE B 188
PHE B 284
ALA B  55
ILE B  45
THR B  42
 None
 1.11A 2rlcA-4mo2B:
undetectable		 2rlcA-4mo2B:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 4mo2 UDP-GALACTOPYRANOSE
MUTASE
(Campylobacter
jejuni) 		5 / 12 ILE B 226
GLY B 230
GLY B 341
TYR B 235
LEU B 213
 None
FDA  B 402 (-3.5A)
None
None
FDA  B 402 ( 4.1A)
 1.20A 2zw9A-4mo2B:
undetectable		 2zw9A-4mo2B:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_C_VIAC901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)		 4mo2 UDP-GALACTOPYRANOSE
MUTASE
(Campylobacter
jejuni) 		4 / 7 TYR B 238
LEU B 327
PHE B 228
VAL B   7
 None
None
None
FDA  B 402 (-4.8A)
 1.07A 3jwqC-4mo2B:
undetectable		 3jwqC-4mo2B:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6D_A_SAMA1350_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 4mo2 UDP-GALACTOPYRANOSE
MUTASE
(Campylobacter
jejuni) 		5 / 12 PHE B 100
LEU B 146
GLY B 139
ILE B 115
ALA B 134
 None
 1.16A 4a6dA-4mo2B:
2.8		 4a6dA-4mo2B:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 4mo2 UDP-GALACTOPYRANOSE
MUTASE
(Campylobacter
jejuni) 		5 / 12 PHE B 100
LEU B 146
GLY B 139
ILE B 115
ALA B 134
 None
 1.13A 4a6eA-4mo2B:
2.4		 4a6eA-4mo2B:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_A_MIYA391_1
(TETX2 PROTEIN)		 4mo2 UDP-GALACTOPYRANOSE
MUTASE
(Campylobacter
jejuni) 		5 / 10 MET B 348
ASN B  39
GLY B  10
GLY B 192
MET B  69
 FDA  B 402 (-4.3A)
FDA  B 402 (-4.2A)
FDA  B 402 (-3.5A)
None
None
 1.49A 4a99A-4mo2B:
12.3		 4a99A-4mo2B:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_B_MIYB391_1
(TETX2 PROTEIN)		 4mo2 UDP-GALACTOPYRANOSE
MUTASE
(Campylobacter
jejuni) 		5 / 11 MET B 348
ASN B  39
GLY B  10
GLY B 192
MET B  69
 FDA  B 402 (-4.3A)
FDA  B 402 (-4.2A)
FDA  B 402 (-3.5A)
None
None
 1.46A 4a99B-4mo2B:
12.3		 4a99B-4mo2B:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_C_MIYC391_1
(TETX2 PROTEIN)		 4mo2 UDP-GALACTOPYRANOSE
MUTASE
(Campylobacter
jejuni) 		5 / 11 MET B 348
ASN B  39
GLY B  10
GLY B 192
MET B  69
 FDA  B 402 (-4.3A)
FDA  B 402 (-4.2A)
FDA  B 402 (-3.5A)
None
None
 1.48A 4a99C-4mo2B:
12.3		 4a99C-4mo2B:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_A_CLQA303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4mo2 UDP-GALACTOPYRANOSE
MUTASE
(Campylobacter
jejuni) 		5 / 12 GLY B 337
GLY B 338
TYR B 346
VAL B 334
ILE B 232
 None
FDA  B 402 (-3.1A)
None
None
None
 1.09A 4fglA-4mo2B:
4.6
4fglB-4mo2B:
4.6		 4fglA-4mo2B:
19.84
4fglB-4mo2B:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_2
(NUPC FAMILY PROTEIN)		 4mo2 UDP-GALACTOPYRANOSE
MUTASE
(Campylobacter
jejuni) 		3 / 3 THR B 289
ASN B  76
PHE B  78
 None
 0.62A 4pd9A-4mo2B:
undetectable		 4pd9A-4mo2B:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_ACTA605_0
(SERUM ALBUMIN)		 4mo2 UDP-GALACTOPYRANOSE
MUTASE
(Campylobacter
jejuni) 		4 / 6 TYR B  53
HIS B  35
GLY B  37
GLU B  31
 None
None
None
FDA  B 402 (-2.7A)
 1.04A 4zbqA-4mo2B:
undetectable		 4zbqA-4mo2B:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4mo2 UDP-GALACTOPYRANOSE
MUTASE
(Campylobacter
jejuni) 		4 / 6 TYR B 345
ILE B  57
TYR B 180
TYR B 150
 FDA  B 402 (-4.6A)
FDA  B 402 (-4.2A)
None
None
 0.91A 5igyA-4mo2B:
undetectable		 5igyA-4mo2B:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4mo2 UDP-GALACTOPYRANOSE
MUTASE
(Campylobacter
jejuni) 		4 / 6 TYR B 345
ILE B  57
TYR B 180
TYR B 150
 FDA  B 402 (-4.6A)
FDA  B 402 (-4.2A)
None
None
 0.98A 5ih0A-4mo2B:
undetectable		 5ih0A-4mo2B:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_A_H98A501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 4mo2 UDP-GALACTOPYRANOSE
MUTASE
(Campylobacter
jejuni) 		5 / 12 VAL B 352
ASP B 198
PHE B 197
PHE B  58
TYR B  68
 None
 1.43A 6iblA-4mo2B:
undetectable		 6iblA-4mo2B:
19.68