SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mo3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4mo3 COAGULATION FACTOR
VIII
(Sus
scrofa) 		4 / 7 SER M2264
VAL M2323
GLY M2242
ILE M2243
 None
 0.86A 1gtnC-4mo3M:
undetectable
1gtnD-4mo3M:
1.3		 1gtnC-4mo3M:
15.34
1gtnD-4mo3M:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_B_THAB2_1
(LIVER
CARBOXYLESTERASE I)		 4mo3 COAGULATION FACTOR
VIII
(Sus
scrofa) 		5 / 11 LEU M2306
VAL M2257
LEU M2321
LEU M2319
LEU M2297
 None
 1.19A 1mx1B-4mo3M:
undetectable		 1mx1B-4mo3M:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_A_HISA302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 4mo3 COAGULATION FACTOR
VIII
(Sus
scrofa) 		5 / 10 GLY M2242
GLU M2322
VAL M2240
LEU M2321
LEU M2234
 None
 1.22A 4yb6A-4mo3M:
undetectable
4yb6E-4mo3M:
undetectable		 4yb6A-4mo3M:
19.53
4yb6E-4mo3M:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_B_HISB302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 4mo3 COAGULATION FACTOR
VIII
(Sus
scrofa) 		5 / 10 GLY M2242
GLU M2322
VAL M2240
LEU M2321
LEU M2234
 None
 1.22A 4yb6B-4mo3M:
undetectable
4yb6C-4mo3M:
undetectable		 4yb6B-4mo3M:
19.53
4yb6C-4mo3M:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_C_HISC302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 4mo3 COAGULATION FACTOR
VIII
(Sus
scrofa) 		5 / 10 GLY M2242
GLU M2322
VAL M2240
LEU M2321
LEU M2234
 None
 1.22A 4yb6C-4mo3M:
undetectable
4yb6F-4mo3M:
undetectable		 4yb6C-4mo3M:
19.53
4yb6F-4mo3M:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_D_HISD302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 4mo3 COAGULATION FACTOR
VIII
(Sus
scrofa) 		5 / 10 LEU M2321
LEU M2234
GLY M2242
GLU M2322
VAL M2240
 None
 1.22A 4yb6A-4mo3M:
undetectable
4yb6D-4mo3M:
undetectable		 4yb6A-4mo3M:
19.53
4yb6D-4mo3M:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_E_HISE302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 4mo3 COAGULATION FACTOR
VIII
(Sus
scrofa) 		5 / 10 LEU M2321
LEU M2234
GLY M2242
GLU M2322
VAL M2240
 None
 1.23A 4yb6D-4mo3M:
undetectable
4yb6E-4mo3M:
undetectable		 4yb6D-4mo3M:
19.53
4yb6E-4mo3M:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_F_HISF302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 4mo3 COAGULATION FACTOR
VIII
(Sus
scrofa) 		5 / 10 LEU M2321
LEU M2234
GLY M2242
GLU M2322
VAL M2240
 None
 1.24A 4yb6B-4mo3M:
undetectable
4yb6F-4mo3M:
undetectable		 4yb6B-4mo3M:
19.53
4yb6F-4mo3M:
19.53