SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4moz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_1
(PROTEASE)		 4moz FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Slackia
heliotrinireduce
ns) 		5 / 10 GLY A 242
ALA A 241
VAL A 211
GLY A 266
ILE A 259
 None
 0.98A 1muiA-4mozA:
undetectable		 1muiA-4mozA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4moz FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Slackia
heliotrinireduce
ns) 		3 / 3 ASP A  52
ASP A  43
ASN A 272
 None
 0.73A 2bm9D-4mozA:
undetectable		 2bm9D-4mozA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6002_0
(PANTOTHENATE KINASE)		 4moz FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Slackia
heliotrinireduce
ns) 		4 / 8 THR A 292
GLY A  78
THR A 285
ILE A 288
 None
 0.97A 2f9wA-4mozA:
undetectable
2f9wB-4mozA:
undetectable		 2f9wA-4mozA:
24.54
2f9wB-4mozA:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_0
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 4moz FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Slackia
heliotrinireduce
ns) 		5 / 12 ALA A  91
GLY A  82
GLY A  85
ALA A  81
LEU A  39
 None
 1.09A 2plwA-4mozA:
undetectable		 2plwA-4mozA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDY_A_RBFA187_1
(LUMAZINE PROTEIN)		 4moz FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Slackia
heliotrinireduce
ns) 		5 / 12 VAL A 246
ASP A 257
GLN A 258
THR A 292
ILE A 288
 None
 1.20A 3ddyA-4mozA:
undetectable		 3ddyA-4mozA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 4moz FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Slackia
heliotrinireduce
ns) 		5 / 12 GLY A 262
GLY A 263
ALA A 229
ILE A 259
PRO A 214
 None
 1.00A 3jayA-4mozA:
undetectable		 3jayA-4mozA:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 4moz FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Slackia
heliotrinireduce
ns) 		5 / 12 ILE A 261
GLY A 262
GLY A 263
ALA A 229
ILE A 259
 None
 0.80A 3jayA-4mozA:
undetectable		 3jayA-4mozA:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB1_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 4moz FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Slackia
heliotrinireduce
ns) 		5 / 12 ILE A 261
GLY A 262
ALA A 229
ILE A 259
PRO A 214
 None
 1.11A 3jb1A-4mozA:
undetectable		 3jb1A-4mozA:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_2
(PROTEASE)		 4moz FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Slackia
heliotrinireduce
ns) 		5 / 10 GLY A 242
ALA A 241
VAL A 211
GLY A 266
ILE A 259
 None
 1.08A 3nu9B-4mozA:
undetectable		 3nu9B-4mozA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGY_A_GLYA510_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4moz FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Slackia
heliotrinireduce
ns) 		4 / 6 ILE A 261
GLU A 224
ALA A 227
ASN A 225
 None
 1.13A 3pgyA-4mozA:
2.5
3pgyB-4mozA:
2.7		 3pgyA-4mozA:
23.70
3pgyB-4mozA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FWD_A_BO2A801_1
(TTC1975 PEPTIDASE)		 4moz FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Slackia
heliotrinireduce
ns) 		5 / 9 VAL A 139
VAL A 138
VAL A 174
ILE A 172
GLY A 170
 None
 1.11A 4fwdA-4mozA:
undetectable		 4fwdA-4mozA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_2
(PROTEASE)		 4moz FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Slackia
heliotrinireduce
ns) 		5 / 10 ALA A 229
VAL A 211
GLY A 199
PRO A 179
ILE A 194
 None
 1.09A 4njuB-4mozA:
undetectable		 4njuB-4mozA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_2
(PROTEASE)		 4moz FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Slackia
heliotrinireduce
ns) 		5 / 10 ALA A 229
VAL A 211
GLY A 199
PRO A 179
ILE A 194
 None
 1.08A 4njuD-4mozA:
undetectable		 4njuD-4mozA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_1
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 4moz FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Slackia
heliotrinireduce
ns) 		3 / 3 SER A 119
TYR A 146
ASP A  43
 None
 0.88A 4rp8C-4mozA:
undetectable		 4rp8C-4mozA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4moz FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Slackia
heliotrinireduce
ns) 		5 / 11 SER A 222
GLN A 254
ALA A 227
GLY A 263
CYH A 240
 None
 1.30A 5bxnV-4mozA:
undetectable
5bxnW-4mozA:
undetectable		 5bxnV-4mozA:
23.10
5bxnW-4mozA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_B_NOVB403_1
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 4moz FRUCTOSE-BISPHOSPHAT
E ALDOLASE
(Slackia
heliotrinireduce
ns) 		4 / 7 PHE A  69
LEU A  68
GLN A  83
GLN A  74
 None
 1.28A 6b89A-4mozA:
1.3		 6b89A-4mozA:
14.66