SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mp3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E73_M_ASCM995_0
(MYROSINASE MA1)		 4mp3 PUTATIVE ORNITHINE
CYCLODEAMINASE
(Staphylococcus
aureus) 		4 / 6 GLN A 154
ILE A 235
PHE A 231
PHE A 162
 None
 1.37A 1e73M-4mp3A:
undetectable		 1e73M-4mp3A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4002_1
(SERUM ALBUMIN)		 4mp3 PUTATIVE ORNITHINE
CYCLODEAMINASE
(Staphylococcus
aureus) 		4 / 4 ARG A  10
ALA A 115
ALA A  95
GLU A  93
 None
 1.11A 1e7bA-4mp3A:
undetectable		 1e7bA-4mp3A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4002_1
(SERUM ALBUMIN)		 4mp3 PUTATIVE ORNITHINE
CYCLODEAMINASE
(Staphylococcus
aureus) 		4 / 4 ARG A  10
ALA A 115
ALA A  95
GLU A  93
 None
 1.10A 1e7bB-4mp3A:
undetectable		 1e7bB-4mp3A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4002_1
(SERUM ALBUMIN)		 4mp3 PUTATIVE ORNITHINE
CYCLODEAMINASE
(Staphylococcus
aureus) 		4 / 5 ARG A  10
ALA A 115
ALA A  95
GLU A  93
 None
 1.09A 1e7cA-4mp3A:
undetectable		 1e7cA-4mp3A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 4mp3 PUTATIVE ORNITHINE
CYCLODEAMINASE
(Staphylococcus
aureus) 		5 / 10 LEU A 304
ASP A 254
LEU A 284
ILE A 292
PHE A 245
 None
 1.31A 1i18A-4mp3A:
undetectable
1i18B-4mp3A:
undetectable		 1i18A-4mp3A:
14.41
1i18B-4mp3A:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 4mp3 PUTATIVE ORNITHINE
CYCLODEAMINASE
(Staphylococcus
aureus) 		5 / 10 PHE A 245
LEU A 304
ASP A 254
LEU A 284
ILE A 292
 None
 1.31A 1i18A-4mp3A:
undetectable
1i18B-4mp3A:
undetectable		 1i18A-4mp3A:
14.41
1i18B-4mp3A:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1320_0
(CHLOROPEROXIDASE)		 4mp3 PUTATIVE ORNITHINE
CYCLODEAMINASE
(Staphylococcus
aureus) 		4 / 6 ALA A 130
PHE A 231
ILE A 302
VAL A 252
 None
 0.98A 2cizA-4mp3A:
undetectable		 2cizA-4mp3A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)		 4mp3 PUTATIVE ORNITHINE
CYCLODEAMINASE
(Staphylococcus
aureus) 		5 / 12 GLY A 330
ILE A 320
GLY A  17
ASN A 328
LEU A   6
 None
 1.17A 3eeyE-4mp3A:
5.4		 3eeyE-4mp3A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 4mp3 PUTATIVE ORNITHINE
CYCLODEAMINASE
(Staphylococcus
aureus) 		5 / 12 GLY A 330
ILE A 320
GLY A  17
ASN A 328
LEU A   6
 None
 1.11A 3eeyF-4mp3A:
4.3		 3eeyF-4mp3A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 4mp3 PUTATIVE ORNITHINE
CYCLODEAMINASE
(Staphylococcus
aureus) 		5 / 12 PHE A 231
ILE A 232
VAL A 210
ILE A 145
VAL A 240
 None
 1.15A 3fpjB-4mp3A:
3.1		 3fpjB-4mp3A:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_D_SAMD1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 4mp3 PUTATIVE ORNITHINE
CYCLODEAMINASE
(Staphylococcus
aureus) 		5 / 10 ILE A 150
THR A 123
ILE A 144
ILE A 211
SER A 233
 GOL  A 402 (-3.9A)
SO4  A 401 ( 4.4A)
None
None
None
 1.34A 3kpbD-4mp3A:
undetectable		 3kpbD-4mp3A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_1
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 4mp3 PUTATIVE ORNITHINE
CYCLODEAMINASE
(Staphylococcus
aureus) 		3 / 3 ARG A  94
ASP A 313
GLN A 258
 GOL  A 402 (-4.0A)
None
None
 0.77A 3lcvB-4mp3A:
4.6		 3lcvB-4mp3A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG305_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4mp3 PUTATIVE ORNITHINE
CYCLODEAMINASE
(Staphylococcus
aureus) 		3 / 3 ASP A  59
ARG A  90
LYS A  83
 None
 1.17A 3wipG-4mp3A:
undetectable		 3wipG-4mp3A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_A_SVRA301_1
(NUCLEOCAPSID PROTEIN)		 4mp3 PUTATIVE ORNITHINE
CYCLODEAMINASE
(Staphylococcus
aureus) 		5 / 11 GLY A  76
ALA A  31
GLN A  42
MET A  64
ILE A  99
 None
None
None
SO4  A 401 (-3.6A)
None
 1.38A 4j4vA-4mp3A:
undetectable		 4j4vA-4mp3A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUF_A_ACTA605_0
(SERUM ALBUMIN)		 4mp3 PUTATIVE ORNITHINE
CYCLODEAMINASE
(Staphylococcus
aureus) 		4 / 4 ALA A 131
HIS A 164
PHE A 162
LEU A 142
 None
 0.82A 4lufA-4mp3A:
0.3		 4lufA-4mp3A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUH_A_ACTA609_0
(SERUM ALBUMIN)		 4mp3 PUTATIVE ORNITHINE
CYCLODEAMINASE
(Staphylococcus
aureus) 		4 / 4 ALA A 131
HIS A 164
PHE A 162
LEU A 142
 None
 0.91A 4luhA-4mp3A:
1.6		 4luhA-4mp3A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_2
(ANDROGEN RECEPTOR)		 4mp3 PUTATIVE ORNITHINE
CYCLODEAMINASE
(Staphylococcus
aureus) 		4 / 7 LEU A 149
ILE A 145
ILE A 144
VAL A 170
 GOL  A 402 (-3.8A)
None
None
None
 0.84A 4ojbA-4mp3A:
undetectable		 4ojbA-4mp3A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4mp3 PUTATIVE ORNITHINE
CYCLODEAMINASE
(Staphylococcus
aureus) 		5 / 12 ALA A  27
ALA A  73
ILE A  68
ILE A 110
LEU A 101
 None
 1.08A 4r3aA-4mp3A:
undetectable		 4r3aA-4mp3A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4mp3 PUTATIVE ORNITHINE
CYCLODEAMINASE
(Staphylococcus
aureus) 		5 / 12 ALA A  27
ALA A  73
ILE A  68
ILE A 110
LEU A 101
 None
 0.98A 4r3aB-4mp3A:
undetectable		 4r3aB-4mp3A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA301_0
(THAUMATIN-1)		 4mp3 PUTATIVE ORNITHINE
CYCLODEAMINASE
(Staphylococcus
aureus) 		3 / 3 THR A 212
ASN A 234
SER A 233
 None
 0.56A 4tvtA-4mp3A:
undetectable		 4tvtA-4mp3A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 4mp3 PUTATIVE ORNITHINE
CYCLODEAMINASE
(Staphylococcus
aureus) 		3 / 3 ASP A 239
ARG A  60
ARG A  94
 None
None
GOL  A 402 (-4.0A)
 0.98A 4x5iA-4mp3A:
0.9		 4x5iA-4mp3A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZF8_A_MYTA502_1
(BIFUNCTIONAL
P-450/NADPH-P450
REDUCTASE)		 4mp3 PUTATIVE ORNITHINE
CYCLODEAMINASE
(Staphylococcus
aureus) 		4 / 6 LEU A 226
ILE A 232
THR A 143
ALA A 203
 None
 0.79A 4zf8A-4mp3A:
undetectable		 4zf8A-4mp3A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6J_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 4mp3 PUTATIVE ORNITHINE
CYCLODEAMINASE
(Staphylococcus
aureus) 		3 / 3 MET A 121
ASP A 152
ARG A 189
 None
 1.16A 5z6jA-4mp3A:
undetectable		 5z6jA-4mp3A:
20.35