SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mp4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		 4mp4 GLUTATHIONE
S-TRANSFERASE
(Acinetobacter
baumannii) 		5 / 12 ILE A 164
LEU A   9
LEU A  63
GLU A  81
LEU A  80
 None
 1.03A 2bxfA-4mp4A:
2.5		 2bxfA-4mp4A:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4mp4 GLUTATHIONE
S-TRANSFERASE
(Acinetobacter
baumannii) 		4 / 6 LEU A 169
GLN A 194
LEU A 143
PHE A 144
 None
 1.03A 2einP-4mp4A:
undetectable
2einW-4mp4A:
undetectable		 2einP-4mp4A:
23.13
2einW-4mp4A:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 4mp4 GLUTATHIONE
S-TRANSFERASE
(Acinetobacter
baumannii) 		4 / 6 ARG A 175
ASP A  12
THR A  11
ASP A  40
 None
 1.23A 2okcB-4mp4A:
undetectable		 2okcB-4mp4A:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)		 4mp4 GLUTATHIONE
S-TRANSFERASE
(Acinetobacter
baumannii) 		5 / 10 THR A  22
GLY A  26
LEU A  77
LEU A  80
ILE A  76
 None
 1.31A 3kvrA-4mp4A:
undetectable		 3kvrA-4mp4A:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_A_URFA400_1
(URIDINE
PHOSPHORYLASE 1)		 4mp4 GLUTATHIONE
S-TRANSFERASE
(Acinetobacter
baumannii) 		5 / 9 THR A  22
GLY A  26
LEU A  77
LEU A  80
ILE A  76
 None
 1.30A 3nbqA-4mp4A:
undetectable		 3nbqA-4mp4A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_D_URFD400_1
(URIDINE
PHOSPHORYLASE 1)		 4mp4 GLUTATHIONE
S-TRANSFERASE
(Acinetobacter
baumannii) 		5 / 9 THR A  22
GLY A  26
LEU A  77
LEU A  80
ILE A  76
 None
 1.30A 3nbqD-4mp4A:
undetectable		 3nbqD-4mp4A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_A_ZMRA1002_2
(NEURAMINIDASE)		 4mp4 GLUTATHIONE
S-TRANSFERASE
(Acinetobacter
baumannii) 		4 / 5 LEU A 132
ARG A 175
ARG A 118
ARG A 115
 None
 1.49A 3ticA-4mp4A:
undetectable		 3ticA-4mp4A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_B_CXQB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 4mp4 GLUTATHIONE
S-TRANSFERASE
(Acinetobacter
baumannii) 		4 / 6 VAL A  23
LEU A  63
LEU A  70
LEU A  83
 None
 0.95A 6f6sA-4mp4A:
undetectable
6f6sB-4mp4A:
undetectable		 6f6sA-4mp4A:
17.79
6f6sB-4mp4A:
15.28