SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mq0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_1
(FTSJ)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		3 / 3 ASP A 431
ASP A 311
ASP A 385
 MMA  A 502 (-3.1A)
None
None
 0.69A 1eizA-4mq0A:
undetectable		 1eizA-4mq0A:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_1
(FTSJ)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		3 / 3 ASP A 431
ASP A 311
ASP A 385
 MMA  A 502 (-3.1A)
None
None
 0.68A 1ej0A-4mq0A:
undetectable		 1ej0A-4mq0A:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK2_A_ACAA91_1
(TISSUE-TYPE
PLASMINOGEN
ACTIVATOR)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		4 / 8 VAL A 172
ASP A 196
LEU A 272
TRP A 175
 None
 1.14A 1pk2A-4mq0A:
undetectable		 1pk2A-4mq0A:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_C_TFPC208_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		4 / 5 PHE A 192
LEU A 244
PHE A 170
SER A 155
 None
 1.23A 1wrlC-4mq0A:
undetectable		 1wrlC-4mq0A:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGQ_A_PCFA1275_0
(WNT INHIBITORY
FACTOR 1)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		5 / 12 LEU A 139
ILE A  95
ILE A 121
PRO A 122
PHE A  43
 None
 0.93A 2ygqA-4mq0A:
undetectable		 2ygqA-4mq0A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		4 / 8 HIS A 426
GLY A 427
TRP A 305
ARG A 428
 None
 1.29A 3ccfA-4mq0A:
undetectable		 3ccfA-4mq0A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		3 / 3 ASP A 431
ASP A 311
ASP A 385
 MMA  A 502 (-3.1A)
None
None
 0.72A 3douA-4mq0A:
undetectable		 3douA-4mq0A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		3 / 3 LYS A  63
ARG A  60
ASP A  88
 None
 1.06A 3o7wA-4mq0A:
undetectable		 3o7wA-4mq0A:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		3 / 3 TYR A 283
ASP A 285
ASP A 166
 MMA  A 503 (-4.2A)
MMA  A 503 (-3.0A)
None
 0.77A 3ou7B-4mq0A:
undetectable		 3ou7B-4mq0A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFE_C_TMGC1_1
(SUCCINATE
DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR SUBUNIT,
MITOCHONDRIAL
SUCCINATE
DEHYDROGENASE
CYTOCHROME B560
SUBUNIT,
MITOCHONDRIAL)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		4 / 8 ILE A 123
TRP A  11
SER A  81
ILE A 144
 None
 0.91A 3sfeB-4mq0A:
undetectable
3sfeC-4mq0A:
undetectable		 3sfeB-4mq0A:
18.85
3sfeC-4mq0A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFE_C_TMGC1_1
(SUCCINATE
DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR SUBUNIT,
MITOCHONDRIAL
SUCCINATE
DEHYDROGENASE
CYTOCHROME B560
SUBUNIT,
MITOCHONDRIAL)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		4 / 8 ILE A 268
TRP A 159
SER A 227
ILE A 289
 None
 0.96A 3sfeB-4mq0A:
undetectable
3sfeC-4mq0A:
undetectable		 3sfeB-4mq0A:
18.85
3sfeC-4mq0A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_A_9PLA501_1
(CYTOCHROME P450 2A6)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		5 / 11 PHE A 276
PHE A 168
PHE A 170
PHE A 246
ILE A 190
 None
 1.12A 3t3rA-4mq0A:
undetectable		 3t3rA-4mq0A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		5 / 9 PHE A 246
PHE A 168
ILE A 287
GLY A 288
PHE A 170
 None
 1.22A 3t3rB-4mq0A:
undetectable		 3t3rB-4mq0A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		5 / 9 PHE A 192
VAL A 273
ILE A 287
GLY A 288
PHE A 170
 None
 1.41A 3t3rC-4mq0A:
undetectable		 3t3rC-4mq0A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		5 / 10 PHE A 246
PHE A 168
ILE A 287
GLY A 288
PHE A 170
 None
 1.17A 3t3rD-4mq0A:
undetectable		 3t3rD-4mq0A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		5 / 10 PHE A 276
PHE A 168
PHE A 170
PHE A 246
ILE A 190
 None
 1.09A 3t3rD-4mq0A:
undetectable		 3t3rD-4mq0A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		5 / 12 ASP A 355
ALA A 429
TYR A 432
GLY A 349
THR A 391
 None
None
MMA  A 502 (-3.8A)
None
None
 1.31A 4mm6A-4mq0A:
undetectable		 4mm6A-4mq0A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		5 / 10 ASP A 355
ALA A 429
TYR A 432
GLY A 357
GLY A 349
 None
None
MMA  A 502 (-3.8A)
None
None
 1.32A 4mmdA-4mq0A:
undetectable		 4mmdA-4mq0A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		5 / 10 VAL A 390
TYR A 378
GLY A 437
SER A 412
GLY A 376
 None
 1.10A 4mmdA-4mq0A:
undetectable		 4mmdA-4mq0A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		5 / 12 VAL A 390
TYR A 378
GLY A 437
SER A 412
GLY A 376
 None
 1.10A 4mmdB-4mq0A:
undetectable		 4mmdB-4mq0A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		5 / 12 ASP A  17
SER A  40
GLY A  16
ASP A 140
GLY A  56
 None
None
MMA  A 501 (-3.3A)
MMA  A 501 (-2.6A)
None
 1.37A 4pevB-4mq0A:
undetectable		 4pevB-4mq0A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		5 / 12 ASP A 285
VAL A 240
GLY A 164
ASP A 165
PHE A 238
 MMA  A 503 (-3.0A)
None
MMA  A 503 (-3.8A)
MMA  A 503 (-2.6A)
MMA  A 503 ( 4.4A)
 1.41A 4pevB-4mq0A:
undetectable		 4pevB-4mq0A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		5 / 12 ASP A 311
SER A 334
GLY A 310
ASP A 434
GLY A 350
 None
None
MMA  A 502 (-3.5A)
MMA  A 502 (-2.6A)
None
 1.34A 4pevB-4mq0A:
undetectable		 4pevB-4mq0A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		4 / 6 ASP A 431
ALA A 429
THR A 389
TYR A 432
 MMA  A 502 (-3.1A)
None
None
MMA  A 502 (-3.8A)
 1.47A 4w5tA-4mq0A:
undetectable		 4w5tA-4mq0A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ5_B_ACTB404_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		3 / 3 TYR A 138
ARG A  60
LYS A  63
 MMA  A 501 (-4.8A)
None
None
 1.41A 4wq5B-4mq0A:
undetectable		 4wq5B-4mq0A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		4 / 6 ASP A 431
ALA A 429
THR A 389
TYR A 432
 MMA  A 502 (-3.1A)
None
None
MMA  A 502 (-3.8A)
 1.48A 4z4cA-4mq0A:
undetectable		 4z4cA-4mq0A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		4 / 5 ASP A 431
ALA A 429
THR A 389
TYR A 432
 MMA  A 502 (-3.1A)
None
None
MMA  A 502 (-3.8A)
 1.47A 4z4gA-4mq0A:
undetectable		 4z4gA-4mq0A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		4 / 5 ASP A 431
ALA A 429
THR A 389
TYR A 432
 MMA  A 502 (-3.1A)
None
None
MMA  A 502 (-3.8A)
 1.46A 4z4hA-4mq0A:
undetectable		 4z4hA-4mq0A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		4 / 6 ASP A 431
ALA A 429
THR A 389
TYR A 432
 MMA  A 502 (-3.1A)
None
None
MMA  A 502 (-3.8A)
 1.45A 4z4iA-4mq0A:
undetectable		 4z4iA-4mq0A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		4 / 6 HIS A 253
VAL A 216
LEU A 225
THR A 248
 None
 1.13A 5ogjA-4mq0A:
undetectable		 5ogjA-4mq0A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		4 / 6 HIS A 253
VAL A 216
LEU A 225
THR A 248
 None
 1.14A 5ogjB-4mq0A:
undetectable		 5ogjB-4mq0A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		4 / 5 HIS A 253
VAL A 216
LEU A 225
THR A 248
 None
 1.14A 5ohhA-4mq0A:
undetectable		 5ohhA-4mq0A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		4 / 6 HIS A 253
VAL A 216
LEU A 225
THR A 248
 None
 1.15A 5ohhB-4mq0A:
undetectable		 5ohhB-4mq0A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FTP_B_DM2B501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 4mq0 PARKIA BIGLOBOSA
LECTIN (PBL)
(Parkia
biglobosa) 		5 / 9 LEU A 244
SER A 245
PHE A 246
LEU A 225
VAL A 181
 None
 1.29A 6ftpA-4mq0A:
undetectable
6ftpB-4mq0A:
undetectable		 6ftpA-4mq0A:
10.91
6ftpB-4mq0A:
6.38