SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mq3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_G_NCTG1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4mq3 INTEGRASE
(Feline
immunodeficiency
virus) 		4 / 8 TYR A  85
TRP A  63
LEU A  76
MET A  65
 None
 1.41A 1uw6G-4mq3A:
undetectable
1uw6H-4mq3A:
undetectable		 1uw6G-4mq3A:
19.42
1uw6H-4mq3A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2L8M_A_CAMA415_0
(CAMPHOR
5-MONOOXYGENASE)		 4mq3 INTEGRASE
(Feline
immunodeficiency
virus) 		5 / 9 THR A  99
LEU A  76
VAL A  77
ASP A 118
VAL A 153
 None
 1.35A 2l8mA-4mq3A:
undetectable		 2l8mA-4mq3A:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4mq3 INTEGRASE
(Feline
immunodeficiency
virus) 		5 / 12 ALA A 102
GLN A 105
VAL A 153
ILE A  79
LEU A 115
 None
 0.97A 3uvvB-4mq3A:
undetectable		 3uvvB-4mq3A:
20.58