SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mqd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 4mqd DNA-ENTRY NUCLEASE
INHIBITOR
(Bacillus
subtilis) 		3 / 3 THR A 112
THR A 124
PRO A 114
 None
 0.79A 1fjaC-4mqdA:
undetectable		 1fjaC-4mqdA:
7.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 4mqd DNA-ENTRY NUCLEASE
INHIBITOR
(Bacillus
subtilis) 		3 / 3 THR A 112
THR A 124
PRO A 114
 None
 0.79A 1fjaD-4mqdA:
undetectable		 1fjaD-4mqdA:
7.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 4mqd DNA-ENTRY NUCLEASE
INHIBITOR
(Bacillus
subtilis) 		3 / 3 THR A 124
PRO A 114
THR A 112
 None
 0.88A 1i3wE-4mqdA:
undetectable		 1i3wE-4mqdA:
7.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 4mqd DNA-ENTRY NUCLEASE
INHIBITOR
(Bacillus
subtilis) 		3 / 3 THR A 112
THR A 124
PRO A 114
 None
 0.84A 1unmE-4mqdA:
undetectable		 1unmE-4mqdA:
7.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 4mqd DNA-ENTRY NUCLEASE
INHIBITOR
(Bacillus
subtilis) 		3 / 3 THR A 124
PRO A 114
THR A 112
 None
 0.87A 1unmF-4mqdA:
undetectable		 1unmF-4mqdA:
7.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 4mqd DNA-ENTRY NUCLEASE
INHIBITOR
(Bacillus
subtilis) 		3 / 3 THR A 112
THR A 124
PRO A 114
 None
 0.83A 1unmF-4mqdA:
undetectable		 1unmF-4mqdA:
7.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 4mqd DNA-ENTRY NUCLEASE
INHIBITOR
(Bacillus
subtilis) 		3 / 3 THR A 112
THR A 124
PRO A 114
 None
 0.73A 209dC-4mqdA:
undetectable		 209dC-4mqdA:
7.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_A_EAAA222_1
(GLUTATHIONE
S-TRANSFERASE P)		 4mqd DNA-ENTRY NUCLEASE
INHIBITOR
(Bacillus
subtilis) 		5 / 10 TYR A 106
VAL A  82
VAL A  19
ASN A  85
GLY A  86
 None
 1.33A 3km6A-4mqdA:
undetectable		 3km6A-4mqdA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_B_EAAB222_1
(GLUTATHIONE
S-TRANSFERASE P)		 4mqd DNA-ENTRY NUCLEASE
INHIBITOR
(Bacillus
subtilis) 		5 / 9 TYR A 106
VAL A  82
VAL A  19
ASN A  85
GLY A  86
 None
 1.32A 3km6B-4mqdA:
undetectable		 3km6B-4mqdA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_A_EAAA214_1
(GLUTATHIONE
S-TRANSFERASE P)		 4mqd DNA-ENTRY NUCLEASE
INHIBITOR
(Bacillus
subtilis) 		5 / 9 TYR A 106
VAL A  82
VAL A  19
ASN A  85
GLY A  86
 None
 1.39A 3kmoA-4mqdA:
undetectable		 3kmoA-4mqdA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_B_EAAB213_1
(GLUTATHIONE
S-TRANSFERASE P)		 4mqd DNA-ENTRY NUCLEASE
INHIBITOR
(Bacillus
subtilis) 		4 / 7 TYR A 106
VAL A  82
ASN A  85
GLY A  86
 None
 0.94A 3kmoB-4mqdA:
undetectable		 3kmoB-4mqdA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I0Y_A_TRPA3001_0
(23S RIBOSOMAL RNA
TRYPTOPHANASE OPERON
LEADER PEPTIDE)		 4mqd DNA-ENTRY NUCLEASE
INHIBITOR
(Bacillus
subtilis) 		3 / 3 TRP A 111
ILE A 127
ASP A 128
 None
 0.85A 6i0y7-4mqdA:
undetectable		 6i0y7-4mqdA:
8.96