SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mrd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4mrd CD44 ANTIGEN
(Mus
musculus) 		4 / 6 ASP A 139
THR A 151
ILE A 150
PHE A  60
 None
 1.07A 4acbC-4mrdA:
undetectable		 4acbC-4mrdA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 4mrd CD44 ANTIGEN
(Mus
musculus) 		3 / 3 PRO A  65
MET A  70
TYR A 122
 None
 0.87A 4qa0B-4mrdA:
undetectable		 4qa0B-4mrdA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 4mrd CD44 ANTIGEN
(Mus
musculus) 		3 / 3 PRO A  65
MET A  70
TYR A 122
 None
 0.86A 4qa0A-4mrdA:
undetectable		 4qa0A-4mrdA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 4mrd CD44 ANTIGEN
(Mus
musculus) 		3 / 3 PRO A  65
MET A  70
TYR A 122
 None
 0.95A 4qa2B-4mrdA:
undetectable		 4qa2B-4mrdA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RKU_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 4mrd CD44 ANTIGEN
(Mus
musculus) 		4 / 8 PHE A  60
SER A  62
ALA A  53
LEU A  56
 None
 1.00A 4rkuA-4mrdA:
undetectable
4rkuJ-4mrdA:
undetectable		 4rkuA-4mrdA:
13.84
4rkuJ-4mrdA:
22.00