SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4msp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1C9H_A_RAPA108_1
(FKBP12.6)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 12 TYR A  33
GLU A  64
TYR A  92
ILE A 100
PHE A 108
 None
 0.63A 1c9hA-4mspA:
17.3		 1c9hA-4mspA:
30.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FAP_A_RAPA108_1
(FK506-BINDING
PROTEIN)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		6 / 12 TYR A  33
GLU A  64
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.71A 1fapA-4mspA:
18.2		 1fapA-4mspA:
32.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 11 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.56A 1fkfA-4mspA:
17.5		 1fkfA-4mspA:
32.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKJ_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 11 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.58A 1fkjA-4mspA:
17.5		 1fkjA-4mspA:
32.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKL_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 12 TYR A  33
GLU A  64
TYR A  92
ILE A 100
PHE A 108
 None
 0.75A 1fklA-4mspA:
18.0		 1fklA-4mspA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKL_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 12 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.52A 1fklA-4mspA:
18.0		 1fklA-4mspA:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBK_A_RAPA225_1
(FKBP25)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 12 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.52A 1pbkA-4mspA:
17.0		 1pbkA-4mspA:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_A_FK5A301_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 9 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.63A 1q6iA-4mspA:
15.3		 1q6iA-4mspA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_B_FK5B401_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 10 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.55A 1q6iB-4mspA:
15.4		 1q6iB-4mspA:
25.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TCO_C_FK5C509_2
(FK506-BINDING
PROTEIN)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 11 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.45A 1tcoC-4mspA:
17.6		 1tcoC-4mspA:
32.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAT_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 11 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.51A 1yatA-4mspA:
18.0		 1yatA-4mspA:
32.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG3_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 11 TYR A  33
GLU A  64
TRP A  69
TYR A  92
PHE A 108
 None
 0.81A 2dg3A-4mspA:
17.9		 2dg3A-4mspA:
32.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FKE_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 11 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.55A 2fkeA-4mspA:
17.6		 2fkeA-4mspA:
32.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VN1_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		6 / 11 TYR A  33
PHE A  44
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.64A 2vn1A-4mspA:
18.0		 2vn1A-4mspA:
31.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		4 / 7 ILE A 110
LEU A  84
PHE A 108
LEU A  43
 None
 0.83A 3adxA-4mspA:
undetectable		 3adxA-4mspA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHZ_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 10 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.51A 3ihzA-4mspA:
18.0		 3ihzA-4mspA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHZ_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 8 TYR A  33
TRP A  69
TYR A  92
GLY A  98
ILE A 100
 None
 0.83A 3ihzB-4mspA:
17.9		 3ihzB-4mspA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KZ7_A_RAPA225_1
(FK506-BINDING
PROTEIN 3)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 10 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.50A 3kz7A-4mspA:
16.9		 3kz7A-4mspA:
27.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O5R_A_FK5A1001_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		6 / 11 TYR A  33
TRP A  69
TYR A  92
LYS A  99
ILE A 100
PHE A 108
 None
 0.71A 3o5rA-4mspA:
16.8		 3o5rA-4mspA:
27.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UF8_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 10 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.41A 3uf8A-4mspA:
18.1		 3uf8A-4mspA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQA_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 10 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.44A 3uqaA-4mspA:
18.2		 3uqaA-4mspA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQB_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 8 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.42A 3uqbA-4mspA:
17.6		 3uqbA-4mspA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAW_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN
SMT3,PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 11 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.57A 3vawA-4mspA:
17.9		 3vawA-4mspA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRH_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		6 / 12 TYR A  33
TRP A  69
TYR A  92
LYS A  99
ILE A 100
PHE A 108
 None
 0.72A 4drhA-4mspA:
16.1		 4drhA-4mspA:
27.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRH_D_RAPD201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 12 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.46A 4drhD-4mspA:
16.3		 4drhD-4mspA:
27.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRI_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 11 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.50A 4driA-4mspA:
17.7		 4driA-4mspA:
27.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRJ_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 11 GLU A  64
TYR A  92
LYS A  99
ILE A 100
PHE A 108
 None
 0.94A 4drjA-4mspA:
17.4		 4drjA-4mspA:
27.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRJ_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		6 / 11 TYR A  33
TRP A  69
TYR A  92
LYS A  99
ILE A 100
PHE A 108
 None
 0.89A 4drjA-4mspA:
17.4		 4drjA-4mspA:
27.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ2_A_FK5A200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 11 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.52A 4dz2A-4mspA:
18.2
4dz2B-4mspA:
18.2		 4dz2A-4mspA:
35.42
4dz2B-4mspA:
35.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ2_B_FK5B200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 11 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.52A 4dz2A-4mspA:
18.2
4dz2B-4mspA:
18.2		 4dz2A-4mspA:
35.42
4dz2B-4mspA:
35.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ3_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 10 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.51A 4dz3A-4mspA:
18.2		 4dz3A-4mspA:
35.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ3_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 10 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.53A 4dz3B-4mspA:
18.1		 4dz3B-4mspA:
35.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAX_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		6 / 10 TYR A  33
TRP A  69
TYR A  92
LYS A  99
ILE A 100
PHE A 108
 None
 0.73A 4laxA-4mspA:
17.6		 4laxA-4mspA:
26.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NNR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		6 / 12 TYR A  33
TRP A  69
TYR A  92
LYS A  99
ILE A 100
PHE A 108
 None
 0.84A 4nnrA-4mspA:
17.1
4nnrB-4mspA:
16.8		 4nnrA-4mspA:
32.51
4nnrB-4mspA:
32.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NNR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		6 / 10 TYR A  33
TRP A  69
TYR A  92
LYS A  99
ILE A 100
PHE A 108
 None
 0.83A 4nnrB-4mspA:
16.8		 4nnrB-4mspA:
32.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QT2_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 10 TYR A  33
GLU A  64
TYR A  92
ILE A 100
PHE A 108
 None
 0.77A 4qt2A-4mspA:
18.0		 4qt2A-4mspA:
26.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QT2_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 10 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.52A 4qt2A-4mspA:
18.0		 4qt2A-4mspA:
26.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QT3_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		6 / 10 TYR A  33
GLU A  64
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.76A 4qt3A-4mspA:
16.4		 4qt3A-4mspA:
26.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_3
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 12 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.37A 5b8iC-4mspA:
17.1		 5b8iC-4mspA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D75_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 11 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.61A 5d75A-4mspA:
17.2		 5d75A-4mspA:
26.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GPG_A_RAPA301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 11 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.57A 5gpgA-4mspA:
17.8		 5gpgA-4mspA:
28.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HKG_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1B)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 12 TYR A  33
GLU A  64
TYR A  92
ILE A 100
PHE A 108
 None
 0.62A 5hkgA-4mspA:
17.4		 5hkgA-4mspA:
30.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_B_FK5B201_1
(FK506-BINDING
PROTEIN 1)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 11 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.46A 5hw8B-4mspA:
17.4		 5hw8B-4mspA:
26.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_C_FK5C201_1
(FK506-BINDING
PROTEIN 1)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 10 TYR A  33
TRP A  69
TYR A  92
LEU A 106
PHE A 108
 None
 0.34A 5hw8C-4mspA:
17.3
5hw8H-4mspA:
14.3		 5hw8C-4mspA:
26.56
5hw8H-4mspA:
26.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_D_FK5D201_1
(FK506-BINDING
PROTEIN 1)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 11 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.42A 5hw8D-4mspA:
17.2		 5hw8D-4mspA:
26.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_2
(FK506-BINDING
PROTEIN 1)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 11 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.36A 5hw8G-4mspA:
17.1		 5hw8G-4mspA:
26.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HWC_A_FK5A201_1
(FK506-BINDING
PROTEIN 1A)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 11 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.47A 5hwcA-4mspA:
17.9		 5hwcA-4mspA:
34.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA607_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		4 / 4 GLY A 118
ARG A  21
ASN A 117
LEU A  28
 None
 0.88A 6b58A-4mspA:
undetectable		 6b58A-4mspA:
16.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_A_FK5A201_0
(PEPTIDYLPROLYL
ISOMERASE)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 12 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.56A 6mkeA-4mspA:
16.9
6mkeD-4mspA:
17.0		 6mkeA-4mspA:
33.71
6mkeD-4mspA:
33.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_B_FK5B201_0
(PEPTIDYLPROLYL
ISOMERASE)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 12 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.58A 6mkeB-4mspA:
17.0
6mkeC-4mspA:
16.9		 6mkeB-4mspA:
33.71
6mkeC-4mspA:
33.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_C_FK5C201_1
(PEPTIDYLPROLYL
ISOMERASE)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 10 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.57A 6mkeC-4mspA:
16.9		 6mkeC-4mspA:
33.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_D_FK5D201_1
(PEPTIDYLPROLYL
ISOMERASE)		 4msp PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP14
(Homo
sapiens) 		5 / 10 TYR A  33
TRP A  69
TYR A  92
ILE A 100
PHE A 108
 None
 0.59A 6mkeD-4mspA:
17.0		 6mkeD-4mspA:
33.71