SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4msx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		 4msx PRE-MRNA-SPLICING
FACTOR SAD1
(Saccharomyces
cerevisiae) 		3 / 3 PHE A  88
TYR A  31
LEU A  94
 None
 0.71A 3keeB-4msxA:
undetectable		 3keeB-4msxA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 4msx PRE-MRNA-SPLICING
FACTOR SAD1
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 423
GLY A 151
LEU A 210
ILE A 407
ALA A 155
 None
 1.04A 4qtuB-4msxA:
undetectable		 4qtuB-4msxA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_0
(CYTOCHROME P450 1A1)		 4msx PRE-MRNA-SPLICING
FACTOR SAD1
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 200
LEU A 193
PHE A 215
PHE A 235
ILE A 421
 None
 1.49A 6dwnB-4msxA:
undetectable		 6dwnB-4msxA:
10.99