SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mt4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA733_1
(ALPHA AMYLASE)		 4mt4 CMEC
(Campylobacter
jejuni) 		4 / 6 SER A 389
ASN A 385
LEU A 381
ASP A 384
 None
 1.30A 1mxdA-4mt4A:
undetectable		 1mxdA-4mt4A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_B_SAMB1400_0
(UPF0088 PROTEIN
AQ_165)		 4mt4 CMEC
(Campylobacter
jejuni) 		5 / 12 LEU A 288
ASN A 286
VAL A 291
GLY A 290
ALA A 136
 None
 0.96A 2egvB-4mt4A:
undetectable		 2egvB-4mt4A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4mt4 CMEC
(Campylobacter
jejuni) 		4 / 7 TYR A  14
GLY A 263
ASN A  18
ASP A 259
 None
 1.04A 2g72B-4mt4A:
undetectable		 2g72B-4mt4A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)		 4mt4 CMEC
(Campylobacter
jejuni) 		3 / 3 SER A 278
HIS A  66
ASP A  59
 None
 0.69A 2wa2B-4mt4A:
undetectable		 2wa2B-4mt4A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UG8_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 4mt4 CMEC
(Campylobacter
jejuni) 		3 / 3 TYR A 187
GLU A 203
TYR A 202
 None
 0.62A 3ug8A-4mt4A:
undetectable		 3ug8A-4mt4A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4mt4 CMEC
(Campylobacter
jejuni) 		4 / 7 GLU A 145
ILE A 460
GLU A 149
PHE A 450
 None
 0.98A 4a97H-4mt4A:
0.0		 4a97H-4mt4A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_A_ACTA1923_0
(BETA-XYLOSIDASE)		 4mt4 CMEC
(Campylobacter
jejuni) 		3 / 3 ASP A 132
ARG A 131
TYR A 287
 None
 0.93A 5a7mA-4mt4A:
undetectable		 5a7mA-4mt4A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_B_ACTB1924_0
(BETA-XYLOSIDASE)		 4mt4 CMEC
(Campylobacter
jejuni) 		3 / 3 ASP A 132
ARG A 131
TYR A 287
 None
 0.94A 5a7mB-4mt4A:
undetectable		 5a7mB-4mt4A:
21.28