SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mtn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4mtn TRANSCRIPTION
TERMINATION FACTOR
NUSA
(Planctopirus
limnophila) 		5 / 9 VAL A 111
GLY A 113
ALA A 132
THR A 116
ILE A 127
 None
 1.25A 1gtnL-4mtnA:
undetectable
1gtnM-4mtnA:
undetectable		 1gtnL-4mtnA:
9.27
1gtnM-4mtnA:
9.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_1
(DIHYDROFOLATE
REDUCTASE)		 4mtn TRANSCRIPTION
TERMINATION FACTOR
NUSA
(Planctopirus
limnophila) 		3 / 3 GLU A 381
GLN A 389
ARG A 392
 None
 0.86A 2w3bB-4mtnA:
undetectable		 2w3bB-4mtnA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFB_B_ACTB501_0
(METHYL-ACCEPTING
CHEMOTAXIS
TRANSDUCER)		 4mtn TRANSCRIPTION
TERMINATION FACTOR
NUSA
(Planctopirus
limnophila) 		4 / 6 ASP A 218
ARG A 247
VAL A 210
ILE A 193
 None
 1.24A 2yfbB-4mtnA:
undetectable		 2yfbB-4mtnA:
25.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 4mtn TRANSCRIPTION
TERMINATION FACTOR
NUSA
(Planctopirus
limnophila) 		5 / 12 ILE A 195
ILE A 185
GLU A 187
ILE A 192
VAL A 208
 None
 1.24A 3fpjB-4mtnA:
undetectable		 3fpjB-4mtnA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 4mtn TRANSCRIPTION
TERMINATION FACTOR
NUSA
(Planctopirus
limnophila) 		5 / 12 GLU A 241
GLY A 239
PHE A 176
ARG A 171
ILE A 243
 None
 1.27A 3k13A-4mtnA:
undetectable		 3k13A-4mtnA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_A_STIA3_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 4mtn TRANSCRIPTION
TERMINATION FACTOR
NUSA
(Planctopirus
limnophila) 		4 / 6 VAL A 188
VAL A 177
ILE A 231
ARG A 196
 None
 1.11A 3pyyA-4mtnA:
undetectable		 3pyyA-4mtnA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4mtn TRANSCRIPTION
TERMINATION FACTOR
NUSA
(Planctopirus
limnophila) 		5 / 12 ILE A  32
ALA A  36
ALA A  35
VAL A   6
ILE A   9
 None
 1.22A 3uvvB-4mtnA:
undetectable		 3uvvB-4mtnA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4mtn TRANSCRIPTION
TERMINATION FACTOR
NUSA
(Planctopirus
limnophila) 		4 / 8 ASP A  73
VAL A   6
SER A  54
GLY A   3
 None
 0.81A 4acaC-4mtnA:
undetectable		 4acaC-4mtnA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4mtn TRANSCRIPTION
TERMINATION FACTOR
NUSA
(Planctopirus
limnophila) 		4 / 8 ILE A  74
ASP A  73
SER A  54
GLY A   3
 None
 0.81A 4acaC-4mtnA:
undetectable		 4acaC-4mtnA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4mtn TRANSCRIPTION
TERMINATION FACTOR
NUSA
(Planctopirus
limnophila) 		4 / 8 ASP A  73
VAL A   6
SER A  54
GLY A   3
 None
 0.82A 4acbC-4mtnA:
undetectable		 4acbC-4mtnA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4mtn TRANSCRIPTION
TERMINATION FACTOR
NUSA
(Planctopirus
limnophila) 		4 / 8 ILE A  74
ASP A  73
SER A  54
GLY A   3
 None
 0.79A 4acbC-4mtnA:
undetectable		 4acbC-4mtnA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G24_A_ACAA1004_1
(PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT2G32230,
MITOCHONDRIAL)		 4mtn TRANSCRIPTION
TERMINATION FACTOR
NUSA
(Planctopirus
limnophila) 		4 / 6 ALA A 259
ASN A 258
LEU A 255
VAL A 254
 None
 1.05A 4g24A-4mtnA:
undetectable		 4g24A-4mtnA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 4mtn TRANSCRIPTION
TERMINATION FACTOR
NUSA
(Planctopirus
limnophila) 		5 / 10 ALA A 259
LEU A 252
LEU A 303
LEU A 299
ALA A 199
 None
 1.15A 4zbrA-4mtnA:
undetectable		 4zbrA-4mtnA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_1
(REGULATORY PROTEIN
TETR)		 4mtn TRANSCRIPTION
TERMINATION FACTOR
NUSA
(Planctopirus
limnophila) 		4 / 8 GLN A  30
GLY A  27
GLU A  22
ILE A  50
 None
 1.08A 5vlmD-4mtnA:
undetectable		 5vlmD-4mtnA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_B_SALB203_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 4mtn TRANSCRIPTION
TERMINATION FACTOR
NUSA
(Planctopirus
limnophila) 		4 / 6 PRO A 219
GLY A 221
ARG A 247
VAL A 210
 None
 0.94A 5x80A-4mtnA:
undetectable
5x80B-4mtnA:
undetectable		 5x80A-4mtnA:
18.27
5x80B-4mtnA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		 4mtn TRANSCRIPTION
TERMINATION FACTOR
NUSA
(Planctopirus
limnophila) 		4 / 7 GLY A   3
SER A  54
GLY A  55
VAL A   6
 None
 0.81A 6ekzA-4mtnA:
undetectable		 6ekzA-4mtnA:
14.24