SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mu9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)		 4mu9 GLYCOSIDE HYDROLASE
FAMILY 73
(Bacteroides
thetaiotaomicron) 		4 / 7 ASP A 141
TYR A  63
ASP A 142
HIS A 196
 EPE  A 408 (-2.9A)
EDO  A 401 ( 4.9A)
EDO  A 401 ( 2.7A)
None
 1.35A 1t03A-4mu9A:
undetectable		 1t03A-4mu9A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_1
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 4mu9 GLYCOSIDE HYDROLASE
FAMILY 73
(Bacteroides
thetaiotaomicron) 		3 / 3 GLY A 358
ASP A 374
ASN A 365
 None
 0.54A 1vq1A-4mu9A:
undetectable		 1vq1A-4mu9A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_2
(MINERALOCORTICOID
RECEPTOR)		 4mu9 GLYCOSIDE HYDROLASE
FAMILY 73
(Bacteroides
thetaiotaomicron) 		3 / 3 LEU A 169
LEU A 148
MET A  86
 None
 0.80A 1ya3B-4mu9A:
undetectable		 1ya3B-4mu9A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMA_A_SAMA375_0
(PROBABLE TRNA
(5-METHYLAMINOMETHYL
-2-THIOURIDYLATE)-ME
THYLTRANSFERASE)		 4mu9 GLYCOSIDE HYDROLASE
FAMILY 73
(Bacteroides
thetaiotaomicron) 		5 / 11 GLY A 363
ASP A 311
ASN A 316
GLY A 358
PHE A 315
 None
 1.08A 2hmaA-4mu9A:
undetectable		 2hmaA-4mu9A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4mu9 GLYCOSIDE HYDROLASE
FAMILY 73
(Bacteroides
thetaiotaomicron) 		4 / 8 GLN A 127
ASP A 142
SER A 128
CYH A 188
 None
EDO  A 401 ( 2.7A)
EDO  A 401 (-4.9A)
None
 0.96A 2xz5A-4mu9A:
undetectable
2xz5C-4mu9A:
undetectable		 2xz5A-4mu9A:
20.34
2xz5C-4mu9A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4mu9 GLYCOSIDE HYDROLASE
FAMILY 73
(Bacteroides
thetaiotaomicron) 		4 / 8 GLN A 127
ASP A 142
SER A 128
CYH A 188
 None
EDO  A 401 ( 2.7A)
EDO  A 401 (-4.9A)
None
 0.95A 2xz5C-4mu9A:
undetectable
2xz5D-4mu9A:
undetectable		 2xz5C-4mu9A:
20.34
2xz5D-4mu9A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I45_A_NIOA500_1
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN)		 4mu9 GLYCOSIDE HYDROLASE
FAMILY 73
(Bacteroides
thetaiotaomicron) 		4 / 8 SER A  77
LEU A  49
TYR A 116
TYR A  82
 None
 1.03A 3i45A-4mu9A:
undetectable		 3i45A-4mu9A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4mu9 GLYCOSIDE HYDROLASE
FAMILY 73
(Bacteroides
thetaiotaomicron) 		4 / 7 GLU A 114
ILE A 146
LEU A 373
MET A  86
 None
 0.95A 4xumA-4mu9A:
undetectable		 4xumA-4mu9A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		 4mu9 GLYCOSIDE HYDROLASE
FAMILY 73
(Bacteroides
thetaiotaomicron) 		4 / 6 LEU A 344
PHE A  27
ILE A  34
PHE A 382
 None
 1.22A 4y4dA-4mu9A:
undetectable		 4y4dA-4mu9A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA610_0
(SERUM ALBUMIN)		 4mu9 GLYCOSIDE HYDROLASE
FAMILY 73
(Bacteroides
thetaiotaomicron) 		3 / 3 TYR A  93
LYS A 102
LYS A  99
 None
 1.19A 5dbyA-4mu9A:
undetectable		 5dbyA-4mu9A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4mu9 GLYCOSIDE HYDROLASE
FAMILY 73
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 133
SER A  77
ALA A  76
THR A  44
 None
 1.33A 5n0tA-4mu9A:
undetectable		 5n0tA-4mu9A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4mu9 GLYCOSIDE HYDROLASE
FAMILY 73
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 133
SER A  77
ALA A  76
THR A  44
 None
 1.31A 5n0wB-4mu9A:
undetectable		 5n0wB-4mu9A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4mu9 GLYCOSIDE HYDROLASE
FAMILY 73
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 133
SER A  77
ALA A  76
THR A  44
 None
 1.33A 5n4iA-4mu9A:
undetectable		 5n4iA-4mu9A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CM4_A_8NUA2001_1
(D(2) DOPAMINE
RECEPTOR, ENDOLYSIN
CHIMERA)		 4mu9 GLYCOSIDE HYDROLASE
FAMILY 73
(Bacteroides
thetaiotaomicron) 		4 / 4 ASP A 244
ALA A 201
SER A 199
PHE A 315
 None
 1.23A 6cm4A-4mu9A:
0.0		 6cm4A-4mu9A:
21.83