SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4muo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_A_SALA3005_1
(XANTHINE
DEHYDROGENASE)		 4muo UNCHARACTERIZED
PROTEIN YBIB
(Escherichia
coli) 		5 / 9 LEU A 187
SER A 200
PHE A 215
VAL A 202
ALA A 212
 None
 1.37A 1fo4A-4muoA:
undetectable		 1fo4A-4muoA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4muo UNCHARACTERIZED
PROTEIN YBIB
(Escherichia
coli) 		5 / 12 THR A 126
PHE A 130
SER A  87
LEU A 199
VAL A 232
 None
 1.34A 1q23C-4muoA:
undetectable		 1q23C-4muoA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_1
(CES1 PROTEIN)		 4muo UNCHARACTERIZED
PROTEIN YBIB
(Escherichia
coli) 		5 / 12 SER A 180
VAL A  45
LEU A  28
LEU A 165
LEU A  42
 None
 1.34A 1ya4B-4muoA:
2.5		 1ya4B-4muoA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_ACTA148_0
(UPF0066 PROTEIN
AF_0241)		 4muo UNCHARACTERIZED
PROTEIN YBIB
(Escherichia
coli) 		3 / 3 VAL A 117
GLU A 119
GLU A 166
 None
 0.67A 2nv4A-4muoA:
undetectable		 2nv4A-4muoA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_4
(PROTEASE RETROPEPSIN)		 4muo UNCHARACTERIZED
PROTEIN YBIB
(Escherichia
coli) 		3 / 3 ASP A 246
THR A 189
PRO A 190
 None
 0.66A 2q64B-4muoA:
undetectable		 2q64B-4muoA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_A_J01A500_1
(ORF12)		 4muo UNCHARACTERIZED
PROTEIN YBIB
(Escherichia
coli) 		4 / 8 LEU A 224
GLY A 209
ALA A 212
LYS A 213
 None
 0.87A 2xfsA-4muoA:
undetectable		 2xfsA-4muoA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1436_1
(ORF12)		 4muo UNCHARACTERIZED
PROTEIN YBIB
(Escherichia
coli) 		4 / 8 LEU A 224
GLY A 209
ALA A 212
LYS A 213
 None
 0.94A 2xh9A-4muoA:
undetectable		 2xh9A-4muoA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		 4muo UNCHARACTERIZED
PROTEIN YBIB
(Escherichia
coli) 		4 / 8 GLU A 193
GLN A  67
VAL A 113
HIS A 115
 None
 1.26A 3b9lA-4muoA:
undetectable		 3b9lA-4muoA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA1001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 4muo UNCHARACTERIZED
PROTEIN YBIB
(Escherichia
coli) 		4 / 5 LEU A 108
GLY A 109
PHE A 110
ARG A 315
 None
 1.13A 3smtA-4muoA:
undetectable		 3smtA-4muoA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_3
(PROTEASE)		 4muo UNCHARACTERIZED
PROTEIN YBIB
(Escherichia
coli) 		3 / 3 ASP A 246
THR A 189
PRO A 190
 None
 0.64A 3tkgD-4muoA:
undetectable		 3tkgD-4muoA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_A_SALA1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4muo UNCHARACTERIZED
PROTEIN YBIB
(Escherichia
coli) 		5 / 9 LEU A 187
SER A 200
PHE A 215
VAL A 202
ALA A 212
 None
 1.36A 3unaA-4muoA:
undetectable		 3unaA-4muoA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4muo UNCHARACTERIZED
PROTEIN YBIB
(Escherichia
coli) 		5 / 9 LEU A 187
SER A 200
PHE A 215
VAL A 202
ALA A 212
 None
 1.35A 3unaB-4muoA:
undetectable		 3unaB-4muoA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_A_SALA1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4muo UNCHARACTERIZED
PROTEIN YBIB
(Escherichia
coli) 		5 / 9 LEU A 187
SER A 200
PHE A 215
VAL A 202
ALA A 212
 None
 1.36A 3uncA-4muoA:
undetectable		 3uncA-4muoA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_B_SALB1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4muo UNCHARACTERIZED
PROTEIN YBIB
(Escherichia
coli) 		5 / 9 LEU A 187
SER A 200
PHE A 215
VAL A 202
ALA A 212
 None
 1.37A 3uncB-4muoA:
undetectable		 3uncB-4muoA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_0U9A601_1
(CHOLESTEROL
24-HYDROXYLASE)		 4muo UNCHARACTERIZED
PROTEIN YBIB
(Escherichia
coli) 		5 / 12 VAL A 112
ALA A 102
THR A  98
GLU A 127
THR A 126
 None
 1.29A 4fiaA-4muoA:
undetectable		 4fiaA-4muoA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_198A602_1
(CHOLESTEROL
24-HYDROXYLASE)		 4muo UNCHARACTERIZED
PROTEIN YBIB
(Escherichia
coli) 		5 / 12 VAL A 112
ALA A 102
THR A  98
GLU A 127
THR A 126
 None
 1.29A 4fiaA-4muoA:
undetectable		 4fiaA-4muoA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_2
(THYROID HORMONE
RECEPTOR ALPHA)		 4muo UNCHARACTERIZED
PROTEIN YBIB
(Escherichia
coli) 		3 / 3 ILE A  47
MET A 171
ARG A 174
 None
 0.83A 4lnwA-4muoA:
undetectable		 4lnwA-4muoA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_2
(THYROID HORMONE
RECEPTOR ALPHA)		 4muo UNCHARACTERIZED
PROTEIN YBIB
(Escherichia
coli) 		3 / 3 ILE A  47
MET A 171
ARG A 174
 None
 0.84A 4lnxA-4muoA:
undetectable		 4lnxA-4muoA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		 4muo UNCHARACTERIZED
PROTEIN YBIB
(Escherichia
coli) 		5 / 12 TYR A  88
TYR A  63
PHE A 161
VAL A 158
THR A 189
 None
 1.32A 4mm6A-4muoA:
undetectable		 4mm6A-4muoA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_2
(ANDROGEN RECEPTOR)		 4muo UNCHARACTERIZED
PROTEIN YBIB
(Escherichia
coli) 		4 / 7 LEU A  97
LEU A 104
ILE A  85
VAL A 112
 None
 0.60A 4ojbA-4muoA:
undetectable		 4ojbA-4muoA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_F_URFF301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 4muo UNCHARACTERIZED
PROTEIN YBIB
(Escherichia
coli) 		3 / 3 ARG A  18
HIS A  16
ARG A  12
 None
 1.05A 5iaoF-4muoA:
undetectable		 5iaoF-4muoA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)		 4muo UNCHARACTERIZED
PROTEIN YBIB
(Escherichia
coli) 		5 / 11 ASN A  96
SER A  87
THR A  98
GLU A 231
LEU A 169
 None
 1.27A 5jh7D-4muoA:
undetectable		 5jh7D-4muoA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 4muo UNCHARACTERIZED
PROTEIN YBIB
(Escherichia
coli) 		3 / 3 LYS A 213
ASP A 217
ARG A 210
 None
 1.08A 5jwaA-4muoA:
3.1
5jwaH-4muoA:
3.1		 5jwaA-4muoA:
21.86
5jwaH-4muoA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 4muo UNCHARACTERIZED
PROTEIN YBIB
(Escherichia
coli) 		5 / 12 ILE A   6
LEU A  33
LEU A  60
LEU A  20
PHE A  62
 None
 1.28A 5xxiA-4muoA:
undetectable		 5xxiA-4muoA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 4muo UNCHARACTERIZED
PROTEIN YBIB
(Escherichia
coli) 		4 / 7 ALA A 222
GLY A 220
GLY A 194
ASN A 243
 None
 0.82A 5ybbB-4muoA:
undetectable		 5ybbB-4muoA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AJI_A_AY6A1001_0
(DRUG EXPORTERS OF
THE RND
SUPERFAMILY-LIKE
PROTEIN,ENDOLYSIN)		 4muo UNCHARACTERIZED
PROTEIN YBIB
(Escherichia
coli) 		5 / 12 LEU A 244
ILE A 242
LEU A 199
VAL A 301
LEU A 197
 None
 0.93A 6ajiA-4muoA:
undetectable		 6ajiA-4muoA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_2
(-)		 4muo UNCHARACTERIZED
PROTEIN YBIB
(Escherichia
coli) 		5 / 12 LEU A 108
LEU A 105
GLY A 312
GLY A 304
PRO A 111
 None
 1.11A 6ce2B-4muoA:
undetectable		 6ce2B-4muoA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA819_0
(GEPHYRIN)		 4muo UNCHARACTERIZED
PROTEIN YBIB
(Escherichia
coli) 		3 / 3 ARG A 221
GLY A 194
GLU A 195
 None
 0.62A 6fgdA-4muoA:
2.9		 6fgdA-4muoA:
23.20