SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mup'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZ4_A_BEZA784_0
(MALT REGULATORY
PROTEIN)		 4mup AMIDOHYDROLASE
(Agrobacterium
fabrum) 		4 / 6 TRP A 237
LEU A 263
LEU A 266
PRO A 267
 None
 1.29A 1hz4A-4mupA:
undetectable		 1hz4A-4mupA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4mup AMIDOHYDROLASE
(Agrobacterium
fabrum) 		5 / 12 ILE A 181
GLY A 175
ASP A 151
ALA A 205
SER A 210
 None
 1.35A 1nbhC-4mupA:
undetectable		 1nbhC-4mupA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 4mup AMIDOHYDROLASE
(Agrobacterium
fabrum) 		4 / 8 ILE A 165
LEU A 200
LYS A 176
GLY A 175
 None
 1.07A 1os6A-4mupA:
undetectable		 1os6A-4mupA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_0
(SUN PROTEIN)		 4mup AMIDOHYDROLASE
(Agrobacterium
fabrum) 		6 / 12 ALA A 126
GLY A 125
GLY A 124
ILE A  97
ASP A  98
GLY A 116
 None
 1.32A 1sqfA-4mupA:
undetectable		 1sqfA-4mupA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4mup AMIDOHYDROLASE
(Agrobacterium
fabrum) 		5 / 12 GLY A  70
ASN A 240
ASN A  71
ALA A  72
ALA A  35
 None
 1.09A 2bm9C-4mupA:
undetectable		 2bm9C-4mupA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_B_ACTB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4mup AMIDOHYDROLASE
(Agrobacterium
fabrum) 		4 / 4 HIS A 243
PRO A 242
ASN A 244
TYR A 208
 None
 1.15A 2f7aB-4mupA:
undetectable		 2f7aB-4mupA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1470_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 4mup AMIDOHYDROLASE
(Agrobacterium
fabrum) 		4 / 5 ARG A 138
ALA A 134
ASP A 133
GLU A 137
 None
 1.32A 2xrzA-4mupA:
undetectable		 2xrzA-4mupA:
25.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJ8_C_SPMC500_1
(DIAMINE
ACETYLTRANSFERASE 1)		 4mup AMIDOHYDROLASE
(Agrobacterium
fabrum) 		4 / 6 ASP A 157
LEU A 162
ASP A 151
LEU A 122
 None
 1.19A 3bj8C-4mupA:
undetectable
3bj8D-4mupA:
undetectable		 3bj8C-4mupA:
18.01
3bj8D-4mupA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_1
(UNCHARACTERIZED
PROTEIN RPA2492)		 4mup AMIDOHYDROLASE
(Agrobacterium
fabrum) 		3 / 3 TYR A 208
ASP A 255
HIS A  27
 None
 0.93A 3e23A-4mupA:
undetectable		 3e23A-4mupA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT201_1
(PROTEIN S100-A4)		 4mup AMIDOHYDROLASE
(Agrobacterium
fabrum) 		4 / 7 PHE A 202
GLY A 198
MET A 188
PHE A 177
 None
 1.13A 3ko0R-4mupA:
undetectable
3ko0T-4mupA:
undetectable		 3ko0R-4mupA:
14.15
3ko0T-4mupA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UM5_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4mup AMIDOHYDROLASE
(Agrobacterium
fabrum) 		5 / 10 VAL A  94
SER A 167
ILE A 165
ILE A 119
THR A  68
 None
 1.11A 3um5A-4mupA:
undetectable		 3um5A-4mupA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4mup AMIDOHYDROLASE
(Agrobacterium
fabrum) 		4 / 5 TYR A 217
VAL A 220
SER A 211
GLY A 206
 None
 1.08A 3v4tA-4mupA:
undetectable
3v4tD-4mupA:
undetectable		 3v4tA-4mupA:
22.40
3v4tD-4mupA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4mup AMIDOHYDROLASE
(Agrobacterium
fabrum) 		5 / 11 ARG A 272
GLY A  20
VAL A 277
GLU A 269
VAL A 289
 None
 1.23A 4d9hA-4mupA:
undetectable		 4d9hA-4mupA:
26.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4mup AMIDOHYDROLASE
(Agrobacterium
fabrum) 		5 / 10 ARG A 272
GLY A  20
VAL A 277
GLU A 269
VAL A 289
 None
 1.27A 4da7A-4mupA:
undetectable		 4da7A-4mupA:
26.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4mup AMIDOHYDROLASE
(Agrobacterium
fabrum) 		5 / 11 ARG A 272
GLY A  20
VAL A 277
GLU A 269
VAL A 289
 None
 1.29A 4danA-4mupA:
undetectable		 4danA-4mupA:
26.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_A_BEZA1000_0
(BENZOATE-COENZYME A
LIGASE)		 4mup AMIDOHYDROLASE
(Agrobacterium
fabrum) 		5 / 7 ALA A  16
ALA A  21
GLY A  20
ILE A  62
GLY A  61
 None
 1.38A 4eatA-4mupA:
undetectable		 4eatA-4mupA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 4mup AMIDOHYDROLASE
(Agrobacterium
fabrum) 		5 / 12 ASP A 172
VAL A 148
PHE A 223
PHE A 171
GLY A 152
 None
 1.46A 4pevC-4mupA:
undetectable		 4pevC-4mupA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_A_1N1A601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4mup AMIDOHYDROLASE
(Agrobacterium
fabrum) 		3 / 3 MET A 145
ASP A 172
PHE A 171
 None
 0.95A 4xeyA-4mupA:
undetectable		 4xeyA-4mupA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_B_1N1B601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4mup AMIDOHYDROLASE
(Agrobacterium
fabrum) 		3 / 3 MET A 145
ASP A 172
PHE A 171
 None
 0.90A 4xeyB-4mupA:
undetectable		 4xeyB-4mupA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZGF_A_BEZA210_0
(UNCHARACTERIZED
PROTEIN)		 4mup AMIDOHYDROLASE
(Agrobacterium
fabrum) 		4 / 4 VAL A 127
ALA A 126
ASN A  71
GLN A  74
 None
 1.33A 4zgfA-4mupA:
undetectable		 4zgfA-4mupA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 4mup AMIDOHYDROLASE
(Agrobacterium
fabrum) 		4 / 6 HIS A 174
VAL A 220
LEU A 261
THR A 262
 None
 1.31A 5ogjA-4mupA:
undetectable		 5ogjA-4mupA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 4mup AMIDOHYDROLASE
(Agrobacterium
fabrum) 		4 / 5 HIS A 174
VAL A 220
LEU A 261
THR A 262
 None
 1.30A 5ohhA-4mupA:
undetectable		 5ohhA-4mupA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 4mup AMIDOHYDROLASE
(Agrobacterium
fabrum) 		4 / 6 HIS A 174
VAL A 220
LEU A 261
THR A 262
 None
 1.31A 5ohhB-4mupA:
undetectable		 5ohhB-4mupA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJY_A_BEZA304_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 4mup AMIDOHYDROLASE
(Agrobacterium
fabrum) 		3 / 3 MET A 106
GLU A 137
ARG A 138
 None
 0.83A 5tjyA-4mupA:
undetectable		 5tjyA-4mupA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJZ_A_BEZA302_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 4mup AMIDOHYDROLASE
(Agrobacterium
fabrum) 		3 / 3 MET A 106
GLU A 137
ARG A 138
 None
 0.93A 5tjzA-4mupA:
undetectable		 5tjzA-4mupA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 4mup AMIDOHYDROLASE
(Agrobacterium
fabrum) 		5 / 12 SER A 210
VAL A 148
PHE A 177
PHE A 223
LEU A 155
 None
 1.29A 5tudD-4mupA:
undetectable		 5tudD-4mupA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B4Y_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		 4mup AMIDOHYDROLASE
(Agrobacterium
fabrum) 		5 / 10 ILE A  66
LEU A  81
VAL A  95
THR A  80
MET A 145
 None
 1.38A 6b4yA-4mupA:
undetectable		 6b4yA-4mupA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_0
(CYTOCHROME P450 1A1)		 4mup AMIDOHYDROLASE
(Agrobacterium
fabrum) 		5 / 12 ILE A  96
LEU A  81
ASN A  77
ASP A  98
ILE A 119
 None
 1.44A 6dwnB-4mupA:
undetectable		 6dwnB-4mupA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA827_0
(GEPHYRIN)		 4mup AMIDOHYDROLASE
(Agrobacterium
fabrum) 		4 / 4 LYS A 203
GLN A  25
GLN A 149
ASP A 172
 None
 0.79A 6fgdA-4mupA:
0.2		 6fgdA-4mupA:
24.07