SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mur'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FP9_A_SAMA401_1 (METHYLTRANSFERASE NSUN4)	4mur	D,D-DIPEPTIDASE/D,D- CARBOXYPEPTIDASE (Enterococcus gallinarum)	3 / 3	ASP A 29 ARG A 56 ASP A 31	None	0.85A	4fp9A-4murA: undetectable	4fp9A-4murA: 17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FP9_C_SAMC401_1 (METHYLTRANSFERASE NSUN4)	4mur	D,D-DIPEPTIDASE/D,D- CARBOXYPEPTIDASE (Enterococcus gallinarum)	3 / 3	ASP A 29 ARG A 56 ASP A 31	None	0.87A	4fp9C-4murA: undetectable	4fp9C-4murA: 17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FP9_F_SAMF401_1 (METHYLTRANSFERASE NSUN4)	4mur	D,D-DIPEPTIDASE/D,D- CARBOXYPEPTIDASE (Enterococcus gallinarum)	3 / 3	ASP A 29 ARG A 56 ASP A 31	None	0.80A	4fp9F-4murA: undetectable	4fp9F-4murA: 17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ESJ_A_TPFA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	4mur	D,D-DIPEPTIDASE/D,D- CARBOXYPEPTIDASE (Enterococcus gallinarum)	4 / 8	PHE A 127 ILE A 55 PHE A 136 LEU A 34	None	0.88A	5esjA-4murA: undetectable	5esjA-4murA: 16.98

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4FP9_A_SAMA401_1","METHYLTRANSFERASE NSUN4","4mur","D,D-DIPEPTIDASE\/D,D-CARBOXYPEPTIDASE","Enterococcus gallinarum",3,"ASP A  29;ARG A  56;ASP A  31","None","0.85A","4fp9A-4murA:undetectable","4fp9A-4murA:17.36"],["4FP9_C_SAMC401_1","METHYLTRANSFERASE NSUN4","4mur","D,D-DIPEPTIDASE\/D,D-CARBOXYPEPTIDASE","Enterococcus gallinarum",3,"ASP A  29;ARG A  56;ASP A  31","None","0.87A","4fp9C-4murA:undetectable","4fp9C-4murA:17.36"],["4FP9_F_SAMF401_1","METHYLTRANSFERASE NSUN4","4mur","D,D-DIPEPTIDASE\/D,D-CARBOXYPEPTIDASE","Enterococcus gallinarum",3,"ASP A  29;ARG A  56;ASP A  31","None","0.80A","4fp9F-4murA:undetectable","4fp9F-4murA:17.36"],["5ESJ_A_TPFA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","4mur","D,D-DIPEPTIDASE\/D,D-CARBOXYPEPTIDASE","Enterococcus gallinarum",4,"PHE A 127;ILE A  55;PHE A 136;LEU A  34","None","0.88A","5esjA-4murA:undetectable","5esjA-4murA:16.98"]]