SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mve'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_2
(MINERALOCORTICOID
RECEPTOR)		 4mve UNCHARACTERIZED
PROTEIN
(Thermomonospora
curvata) 		3 / 3 LEU A  75
LEU A  92
MET A 108
 None
 0.60A 1ya3B-4mveA:
undetectable		 1ya3B-4mveA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNC_A_CLUA808_1
(COPPER AMINE
OXIDASE, LIVER
ISOZYME)		 4mve UNCHARACTERIZED
PROTEIN
(Thermomonospora
curvata) 		4 / 7 ALA A 130
TYR A  26
TYR A 141
HIS A 118
 None
 1.47A 2pncA-4mveA:
undetectable		 2pncA-4mveA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 4mve UNCHARACTERIZED
PROTEIN
(Thermomonospora
curvata) 		4 / 6 TYR A  87
PRO A  74
ILE A 115
LEU A  52
 None
 1.29A 2wekB-4mveA:
undetectable		 2wekB-4mveA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_A_GAIA407_0
(PROTEIN (ARGINASE))		 4mve UNCHARACTERIZED
PROTEIN
(Thermomonospora
curvata) 		4 / 6 ARG A   6
GLU A   4
LEU A  29
ASP A   2
 None
 1.08A 4cevA-4mveA:
undetectable
4cevB-4mveA:
undetectable		 4cevA-4mveA:
21.48
4cevB-4mveA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_D_GAID410_0
(PROTEIN (ARGINASE))		 4mve UNCHARACTERIZED
PROTEIN
(Thermomonospora
curvata) 		4 / 6 ARG A   6
GLU A   4
LEU A  29
ASP A   2
 None
 1.09A 4cevD-4mveA:
undetectable
4cevE-4mveA:
undetectable		 4cevD-4mveA:
21.48
4cevE-4mveA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_F_GAIF411_0
(PROTEIN (ARGINASE))		 4mve UNCHARACTERIZED
PROTEIN
(Thermomonospora
curvata) 		4 / 6 ARG A   6
GLU A   4
LEU A  29
ASP A   2
 None
 1.10A 4cevE-4mveA:
undetectable
4cevF-4mveA:
undetectable		 4cevE-4mveA:
21.48
4cevF-4mveA:
21.48