SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mvu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KZ7_A_RAPA225_1
(FK506-BINDING
PROTEIN 3)		 4mvu ION TRANSPORT
PROTEIN
(Arcobacter
butzleri) 		5 / 10 TYR A1020
LEU A1024
VAL A1052
ILE A1055
PHE A1017
 None
 1.04A 3kz7A-4mvuA:
undetectable		 3kz7A-4mvuA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQB_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4mvu ION TRANSPORT
PROTEIN
(Arcobacter
butzleri) 		4 / 8 TYR A1020
VAL A1052
ILE A1055
PHE A1017
 None
 0.86A 3uqbA-4mvuA:
undetectable		 3uqbA-4mvuA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)		 4mvu ION TRANSPORT
PROTEIN
(Arcobacter
butzleri) 		3 / 3 LEU A1024
MET A1029
TYR A1044
 None
 0.96A 4p6xG-4mvuA:
undetectable		 4p6xG-4mvuA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D75_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 4mvu ION TRANSPORT
PROTEIN
(Arcobacter
butzleri) 		5 / 11 TYR A1020
LEU A1024
VAL A1052
ILE A1055
PHE A1017
 None
 1.14A 5d75A-4mvuA:
undetectable		 5d75A-4mvuA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GPG_A_RAPA301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 4mvu ION TRANSPORT
PROTEIN
(Arcobacter
butzleri) 		5 / 11 TYR A1020
LEU A1024
VAL A1052
ILE A1055
PHE A1017
 None
 1.11A 5gpgA-4mvuA:
undetectable		 5gpgA-4mvuA:
20.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KMF_A_6U9A1301_1
(ION TRANSPORT
PROTEIN)		 4mvu ION TRANSPORT
PROTEIN
(Arcobacter
butzleri) 		4 / 6 THR A1162
GLY A1164
GLU A1165
PHE A1167
 PX4  A1303 (-3.8A)
PX4  A1303 (-3.3A)
PX4  A1303 ( 4.5A)
None
 0.25A 5kmfA-4mvuA:
24.2
5kmfC-4mvuA:
24.8		 5kmfA-4mvuA:
98.31
5kmfC-4mvuA:
98.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		 4mvu ION TRANSPORT
PROTEIN
(Arcobacter
butzleri) 		4 / 6 MET A1174
THR A1175
LEU A1176
MET A1209
 PX4  A1304 ( 4.8A)
None
None
PX4  A1304 ( 4.6A)
 0.71A 6mvxA-4mvuA:
22.3
6mvxB-4mvuA:
22.8
6mvxC-4mvuA:
22.5		 6mvxA-4mvuA:
99.58
6mvxB-4mvuA:
99.58
6mvxC-4mvuA:
99.58