SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mxn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4mxn UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		5 / 10 ALA A 108
ALA A 104
LEU A 169
VAL A 190
ILE A 122
 None
 1.16A 1claA-4mxnA:
undetectable		 1claA-4mxnA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 4mxn UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		5 / 11 VAL A 187
ILE A 202
ILE A 204
VAL A 246
PHE A 217
 None
 1.24A 1gx9A-4mxnA:
undetectable		 1gx9A-4mxnA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 4mxn UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		5 / 11 HIS A 183
MET A 212
VAL A 162
CYH A 207
ILE A 204
 None
 1.14A 2uxpB-4mxnA:
undetectable		 2uxpB-4mxnA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM8_A_ACAA511_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4mxn UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		4 / 8 ALA A 152
ILE A 154
ILE A 178
TYR A 179
 None
 0.86A 2zm8A-4mxnA:
undetectable		 2zm8A-4mxnA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMA_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4mxn UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		4 / 8 ALA A 152
ILE A 154
ILE A 178
TYR A 179
 None
 0.87A 2zmaA-4mxnA:
undetectable		 2zmaA-4mxnA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OAP_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4mxn UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		6 / 12 ILE A 154
ALA A 176
ALA A 152
LEU A 169
VAL A 162
ILE A 114
 None
 1.27A 3oapA-4mxnA:
undetectable		 3oapA-4mxnA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA409_0
(FAD:PROTEIN FMN
TRANSFERASE)		 4mxn UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		4 / 5 ILE A  51
VAL A  77
ILE A  79
VAL A  48
 None
 0.65A 4xdtA-4mxnA:
undetectable		 4xdtA-4mxnA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)		 4mxn UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		5 / 12 ILE A  71
ILE A 106
ILE A 122
VAL A  90
LEU A  39
 None
 1.21A 4y0pA-4mxnA:
undetectable		 4y0pA-4mxnA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGW_A_CTYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4mxn UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		5 / 12 ILE A 116
GLY A 117
GLU A  72
SER A  52
ILE A  51
 None
 1.38A 5igwA-4mxnA:
undetectable		 5igwA-4mxnA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_2
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)		 4mxn UNCHARACTERIZED
PROTEIN
(Parabacteroides
merdae) 		4 / 4 VAL A  37
LEU A  67
LEU A  39
ASP A  95
 None
 1.45A 5xv7A-4mxnA:
undetectable		 5xv7A-4mxnA:
15.38