SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4myr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_ACTA1181_0
(WNT INHIBITORY
FACTOR 1)		 4myr CPAE2 PILUS ASSEMBLY
PROTEIN
(Sinorhizobium
meliloti) 		3 / 3 TYR A  74
VAL A  83
THR A  78
 None
 0.87A 2ygnA-4myrA:
undetectable		 2ygnA-4myrA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RET_A_SALA201_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 4myr CPAE2 PILUS ASSEMBLY
PROTEIN
(Sinorhizobium
meliloti) 		5 / 10 VAL A  35
ALA A 147
VAL A 145
MET A  55
ILE A  33
 None
 1.35A 3retA-4myrA:
undetectable
3retB-4myrA:
undetectable		 3retA-4myrA:
21.58
3retB-4myrA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J2T_C_VLBC503_1
(TUBULIN BETA-2B
CHAIN
TUBULIN ALPHA-1B
CHAIN)		 4myr CPAE2 PILUS ASSEMBLY
PROTEIN
(Sinorhizobium
meliloti) 		5 / 9 VAL A  83
ASP A  32
THR A 107
TYR A  74
LEU A 101
 None
 1.28A 5j2tB-4myrA:
2.3		 5j2tB-4myrA:
16.90