SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4myw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_A_BEZA881_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 4myw ENVELOPE
GLYCOPROTEIN D
(Human
alphaherpesvirus
2) 		5 / 11 ASP A  30
PRO A 225
TYR A 115
ARG A 130
VAL A  34
 None
 1.31A 1tmxA-4mywA:
undetectable		 1tmxA-4mywA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_B_BEZB882_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 4myw ENVELOPE
GLYCOPROTEIN D
(Human
alphaherpesvirus
2) 		5 / 12 ASP A  30
PRO A 225
TYR A 115
ARG A 130
VAL A  34
 None
 1.35A 1tmxB-4mywA:
undetectable		 1tmxB-4mywA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4myw ENVELOPE
GLYCOPROTEIN D
(Human
alphaherpesvirus
2) 		5 / 12 VAL A 212
THR A  96
VAL A 168
SER A  75
TYR A 100
 None
 1.40A 2y00B-4mywA:
undetectable		 2y00B-4mywA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4myw ENVELOPE
GLYCOPROTEIN D
(Human
alphaherpesvirus
2) 		5 / 12 VAL A 212
THR A  96
VAL A 168
SER A  75
TYR A 100
 None
 1.40A 2y01B-4mywA:
undetectable		 2y01B-4mywA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4myw ENVELOPE
GLYCOPROTEIN D
(Human
alphaherpesvirus
2) 		5 / 12 ALA A 155
SER A 142
LEU A 236
ALA A  65
TRP A 241
 None
 1.03A 3ou7B-4mywA:
undetectable		 3ou7B-4mywA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 4myw ENVELOPE
GLYCOPROTEIN D
(Human
alphaherpesvirus
2) 		3 / 3 ARG A  36
PRO A 225
ASN A 148
 None
 1.06A 5jwaA-4mywA:
undetectable
5jwaH-4mywA:
undetectable		 5jwaA-4mywA:
18.66
5jwaH-4mywA:
18.66