SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mz0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_A_ADNA601_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)
4mz0 CURL
(Moorea
producens)
5 / 12 THR A 495
ASP A 914
LEU A 895
LEU A 493
GLY A 899
None
1.32A 1d4fA-4mz0A:
undetectable
1d4fA-4mz0A:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_1
(TRANSTHYRETIN)
4mz0 CURL
(Moorea
producens)
4 / 7 LEU A 238
LEU A 240
SER A 241
THR A 244
None
0.97A 1dvxA-4mz0A:
undetectable
1dvxA-4mz0A:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)
4mz0 CURL
(Moorea
producens)
4 / 7 LEU A 238
LEU A 240
SER A 241
THR A 244
None
0.97A 1dvxB-4mz0A:
undetectable
1dvxB-4mz0A:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)
4mz0 CURL
(Moorea
producens)
3 / 3 ARG A 129
ILE A 936
TRP A 935
None
1.16A 1m8eB-4mz0A:
undetectable
1m8eB-4mz0A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_2
(LIVER
CARBOXYLESTERASE I)
4mz0 CURL
(Moorea
producens)
3 / 3 PHE A 913
LEU A 898
MET A 903
None
0.88A 1mx1D-4mz0A:
undetectable
1mx1D-4mz0A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_B_SAMB301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)
4mz0 CURL
(Moorea
producens)
4 / 4 LEU A 895
SER A 668
ASP A 914
ASP A 525
None
1.35A 2br4B-4mz0A:
undetectable
2br4B-4mz0A:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1216_1
(LIPOPROTEIN LPPX)
4mz0 CURL
(Moorea
producens)
4 / 5 LEU A 848
ILE A 813
LEU A 812
SER A 811
None
0.92A 2byoA-4mz0A:
undetectable
2byoA-4mz0A:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_B_BEZB143_0
(PUTATIVE REDOX
PROTEIN)
4mz0 CURL
(Moorea
producens)
4 / 6 ARG A 840
THR A 752
ALA A 745
PRO A 749
None
1.42A 2ql8A-4mz0A:
undetectable
2ql8B-4mz0A:
undetectable
2ql8A-4mz0A:
9.74
2ql8B-4mz0A:
9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_A_X2NA1480_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)
4mz0 CURL
(Moorea
producens)
5 / 12 TYR A 660
PHE A 656
PHE A 585
ALA A 703
ALA A 690
None
1.12A 2x2nA-4mz0A:
undetectable
2x2nA-4mz0A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)
4mz0 CURL
(Moorea
producens)
4 / 7 PRO A 335
SER A 337
ILE A 443
GLY A 332
None
0.95A 2y7kA-4mz0A:
undetectable
2y7kA-4mz0A:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)
4mz0 CURL
(Moorea
producens)
4 / 8 LEU A 124
SER A 123
ALA A 187
ALA A 184
None
0.91A 3ax9B-4mz0A:
undetectable
3ax9B-4mz0A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_1
(ADENOSYLHOMOCYSTEINA
SE)
4mz0 CURL
(Moorea
producens)
5 / 12 THR A 495
ASP A 914
LEU A 895
LEU A 493
GLY A 899
None
1.32A 3ce6B-4mz0A:
undetectable
3ce6B-4mz0A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E68_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)
4mz0 CURL
(Moorea
producens)
3 / 3 ARG A 129
ILE A 936
TRP A 935
None
1.16A 3e68A-4mz0A:
0.0
3e68A-4mz0A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)
4mz0 CURL
(Moorea
producens)
3 / 3 ARG A 129
ILE A 936
TRP A 935
None
1.19A 3e6tB-4mz0A:
undetectable
3e6tB-4mz0A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_A_ADNA438_1
(ADENOSYLHOMOCYSTEINA
SE)
4mz0 CURL
(Moorea
producens)
5 / 12 THR A 495
ASP A 914
LEU A 895
LEU A 493
GLY A 899
None
1.15A 3g1uA-4mz0A:
undetectable
3g1uA-4mz0A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_1
(ADENOSYLHOMOCYSTEINA
SE)
4mz0 CURL
(Moorea
producens)
5 / 12 THR A 495
ASP A 914
LEU A 895
LEU A 493
GLY A 899
None
1.30A 3g1uB-4mz0A:
undetectable
3g1uB-4mz0A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)
4mz0 CURL
(Moorea
producens)
5 / 12 THR A 495
ASP A 914
LEU A 895
LEU A 493
GLY A 899
None
1.28A 3g1uC-4mz0A:
undetectable
3g1uC-4mz0A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)
4mz0 CURL
(Moorea
producens)
5 / 12 THR A 495
ASP A 914
LEU A 895
LEU A 493
GLY A 899
None
1.27A 3g1uD-4mz0A:
undetectable
3g1uD-4mz0A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_0
(PCZA361.24)
4mz0 CURL
(Moorea
producens)
5 / 12 GLU A 858
LEU A 865
LEU A 884
GLY A 589
SER A 590
None
1.10A 3g2oA-4mz0A:
undetectable
3g2oA-4mz0A:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_1
(ADENOSYLHOMOCYSTEINA
SE)
4mz0 CURL
(Moorea
producens)
5 / 12 THR A 495
ASP A 914
LEU A 895
LEU A 493
GLY A 899
None
1.32A 3glqA-4mz0A:
undetectable
3glqA-4mz0A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_1
(ADENOSYLHOMOCYSTEINA
SE)
4mz0 CURL
(Moorea
producens)
5 / 12 THR A 495
ASP A 914
LEU A 895
LEU A 493
GLY A 899
None
1.33A 3glqB-4mz0A:
undetectable
3glqB-4mz0A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)
4mz0 CURL
(Moorea
producens)
5 / 12 SER A 827
GLU A 824
ARG A 840
VAL A 839
ASN A 833
None
1.43A 3jb3A-4mz0A:
2.1
3jb3A-4mz0A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)
4mz0 CURL
(Moorea
producens)
5 / 12 THR A 495
ASP A 914
LEU A 895
LEU A 493
GLY A 899
None
1.30A 3n58A-4mz0A:
undetectable
3n58A-4mz0A:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_1
(ADENOSYLHOMOCYSTEINA
SE)
4mz0 CURL
(Moorea
producens)
5 / 12 THR A 495
ASP A 914
LEU A 895
LEU A 493
GLY A 899
None
1.33A 3n58C-4mz0A:
undetectable
3n58C-4mz0A:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)
4mz0 CURL
(Moorea
producens)
3 / 3 PHE A 784
SER A 680
GLN A 652
None
0.97A 3smtA-4mz0A:
undetectable
3smtA-4mz0A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_0
(WBDD)
4mz0 CURL
(Moorea
producens)
5 / 12 GLY A 393
ALA A 389
SER A 447
VAL A 446
ILE A 460
None
0.95A 4ax8A-4mz0A:
undetectable
4ax8A-4mz0A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_0
(WBDD)
4mz0 CURL
(Moorea
producens)
5 / 12 GLY A 393
ALA A 389
SER A 447
VAL A 446
ILE A 460
None
0.92A 4azvA-4mz0A:
undetectable
4azvA-4mz0A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUB_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)
4mz0 CURL
(Moorea
producens)
3 / 3 TYR A 528
ARG A 522
HIS A 920
None
1.22A 4fubA-4mz0A:
undetectable
4fubA-4mz0A:
14.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA500_2
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)
4mz0 CURL
(Moorea
producens)
4 / 4 LEU A 295
LEU A 394
GLN A 404
GLU A 461
None
1.16A 4i41A-4mz0A:
undetectable
4i41A-4mz0A:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LS7_A_1X9A504_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)
4mz0 CURL
(Moorea
producens)
8 / 12 ALA A 208
CYH A 209
PHE A 248
HIS A 344
THR A 346
HIS A 384
GLY A 450
PHE A 451
None
0.81A 4ls7A-4mz0A:
49.9
4ls7A-4mz0A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LS7_B_1X9B503_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)
4mz0 CURL
(Moorea
producens)
8 / 12 ALA A 208
CYH A 209
PHE A 248
HIS A 344
THR A 346
HIS A 384
GLY A 450
PHE A 451
None
0.79A 4ls7A-4mz0A:
49.9
4ls7B-4mz0A:
49.7
4ls7A-4mz0A:
17.39
4ls7B-4mz0A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_A_ACTA401_0
(PROTON-GATED ION
CHANNEL)
4mz0 CURL
(Moorea
producens)
4 / 6 ILE A 419
PHE A 263
ILE A 359
GLU A 355
None
1.21A 4zzcA-4mz0A:
undetectable
4zzcB-4mz0A:
undetectable
4zzcA-4mz0A:
16.83
4zzcB-4mz0A:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_B_ACTB401_0
(PROTON-GATED ION
CHANNEL)
4mz0 CURL
(Moorea
producens)
4 / 6 ILE A 419
PHE A 263
ILE A 359
GLU A 355
None
1.27A 4zzcB-4mz0A:
undetectable
4zzcC-4mz0A:
undetectable
4zzcB-4mz0A:
16.83
4zzcC-4mz0A:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)
4mz0 CURL
(Moorea
producens)
5 / 12 LEU A 424
ASN A 316
LEU A 328
PHE A 363
ILE A 324
None
1.14A 5dv4A-4mz0A:
undetectable
5dv4A-4mz0A:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_B_SAMB801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)
4mz0 CURL
(Moorea
producens)
5 / 11 ILE A  71
GLY A 101
ALA A  70
PHE A  60
VAL A  68
None
1.19A 5hw4B-4mz0A:
undetectable
5hw4B-4mz0A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_1
(CDL2.3B)
4mz0 CURL
(Moorea
producens)
5 / 12 LEU A 884
TYR A 629
LEU A 624
ALA A 609
LEU A 695
None
1.05A 5iepA-4mz0A:
undetectable
5iepA-4mz0A:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS5_A_ASCA202_0
(CYTOCHROME C')
4mz0 CURL
(Moorea
producens)
3 / 3 CYH A 260
LYS A 261
HIS A 411
None
1.23A 5js5A-4mz0A:
undetectable
5js5A-4mz0A:
8.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
4mz0 CURL
(Moorea
producens)
5 / 11 ILE A 460
ILE A 298
VAL A 398
ILE A 279
ALA A 233
None
0.98A 5lg3A-4mz0A:
undetectable
5lg3A-4mz0A:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_E_Z80E401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
4mz0 CURL
(Moorea
producens)
5 / 12 ILE A 460
ILE A 298
VAL A 398
ILE A 279
ALA A 233
None
0.95A 5lg3E-4mz0A:
undetectable
5lg3E-4mz0A:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)
4mz0 CURL
(Moorea
producens)
5 / 12 ILE A 391
GLY A 234
ALA A 388
ALA A 392
MET A 395
None
1.02A 5n0tB-4mz0A:
undetectable
5n0tB-4mz0A:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_1_PQN1842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)
4mz0 CURL
(Moorea
producens)
5 / 10 SER A 448
LEU A 394
GLY A 393
ILE A 144
LEU A 149
None
1.21A 5oy01-4mz0A:
undetectable
5oy07-4mz0A:
undetectable
5oy01-4mz0A:
6.60
5oy07-4mz0A:
3.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_1
(PROTEIN CYP51)
4mz0 CURL
(Moorea
producens)
5 / 12 PHE A 537
ALA A 233
ALA A 231
THR A 154
LEU A 149
None
1.21A 5tl8A-4mz0A:
undetectable
5tl8A-4mz0A:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)
4mz0 CURL
(Moorea
producens)
4 / 8 VAL A 278
LEU A 192
THR A 189
ALA A 188
None
0.92A 5tt3H-4mz0A:
undetectable
5tt3H-4mz0A:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_A_SAMA402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)
4mz0 CURL
(Moorea
producens)
5 / 12 SER A 447
GLY A 393
ALA A 392
SER A 211
GLU A 355
None
1.43A 5wbvA-4mz0A:
undetectable
5wbvA-4mz0A:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)
4mz0 CURL
(Moorea
producens)
5 / 12 SER A 447
GLY A 393
ALA A 392
SER A 211
GLU A 355
None
1.44A 5wbvB-4mz0A:
1.0
5wbvB-4mz0A:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)
4mz0 CURL
(Moorea
producens)
5 / 12 LEU A 284
VAL A 294
PRO A 464
THR A 437
GLY A 439
None
1.04A 5xipA-4mz0A:
undetectable
5xipA-4mz0A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_C_HFGC1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)
4mz0 CURL
(Moorea
producens)
5 / 12 LEU A 284
VAL A 294
PRO A 464
THR A 437
GLY A 439
None
1.10A 5xipC-4mz0A:
2.1
5xipC-4mz0A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_A_HFGA1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))
4mz0 CURL
(Moorea
producens)
5 / 12 LEU A 284
VAL A 294
PRO A 464
THR A 437
GLY A 439
None
1.02A 5xiqA-4mz0A:
undetectable
5xiqA-4mz0A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))
4mz0 CURL
(Moorea
producens)
5 / 12 LEU A 284
VAL A 294
PRO A 464
THR A 437
GLY A 439
None
1.09A 5xiqD-4mz0A:
undetectable
5xiqD-4mz0A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_0
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)
4mz0 CURL
(Moorea
producens)
5 / 12 GLY A 587
THR A 586
GLY A 682
THR A 648
PHE A 784
None
1.15A 5ybbA-4mz0A:
undetectable
5ybbA-4mz0A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_A_ESTA601_1
(ESTROGEN RECEPTOR)
4mz0 CURL
(Moorea
producens)
4 / 8 GLU A 795
LEU A 708
MET A 709
LEU A 701
None
1.14A 6cbzA-4mz0A:
undetectable
6cbzA-4mz0A:
6.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EF6_A_BEZA401_0
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)
4mz0 CURL
(Moorea
producens)
5 / 9 LEU A 192
SER A 193
THR A 189
ILE A 158
VAL A 278
None
1.24A 6ef6A-4mz0A:
undetectable
6ef6A-4mz0A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_A_ADNA505_1
(-)
4mz0 CURL
(Moorea
producens)
5 / 12 THR A 495
ASP A 914
LEU A 895
LEU A 493
GLY A 899
None
1.32A 6f3nA-4mz0A:
undetectable
6f3nA-4mz0A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_C_ADNC505_1
(-)
4mz0 CURL
(Moorea
producens)
5 / 12 THR A 495
ASP A 914
LEU A 895
LEU A 493
GLY A 899
None
1.30A 6f3nC-4mz0A:
undetectable
6f3nC-4mz0A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_D_ADND506_1
(-)
4mz0 CURL
(Moorea
producens)
5 / 12 THR A 495
ASP A 914
LEU A 895
LEU A 493
GLY A 899
None
1.32A 6f3nD-4mz0A:
undetectable
6f3nD-4mz0A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_A_ACRA602_1
(-)
4mz0 CURL
(Moorea
producens)
5 / 12 GLY A 234
GLY A 235
VAL A 387
ASN A 237
GLY A 275
None
1.09A 6gneA-4mz0A:
undetectable
6gneA-4mz0A:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_1
(-)
4mz0 CURL
(Moorea
producens)
5 / 12 GLY A 234
GLY A 235
VAL A 387
ASN A 237
GLY A 275
None
1.08A 6gneB-4mz0A:
undetectable
6gneB-4mz0A:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_A_LLLA301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)
4mz0 CURL
(Moorea
producens)
4 / 6 TYR A 518
GLU A  58
CYH A  48
GLU A 137
None
1.37A 6mn5A-4mz0A:
2.1
6mn5A-4mz0A:
5.57