SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mz1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IEP_A_STIA201_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
4 / 6 LYS A 261
VAL A 242
VAL A 234
ILE A 260
None
0.99A 1iepA-4mz1A:
undetectable
1iepA-4mz1A:
22.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JR1_A_MOAA1332_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
5 / 11 ASN A 273
GLY A 296
CYH A 301
THR A 303
GLY A 385
IMP  A 500 ( 4.1A)
None
IMP  A 500 ( 3.1A)
2F1  A 501 (-4.1A)
IMP  A 500 ( 3.3A)
0.35A 1jr1A-4mz1A:
53.8
1jr1A-4mz1A:
37.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JR1_A_MOAA1332_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
5 / 11 ASP A 244
ASN A 273
GLY A 296
THR A 303
GLY A 385
None
IMP  A 500 ( 4.1A)
None
2F1  A 501 (-4.1A)
IMP  A 500 ( 3.3A)
0.78A 1jr1A-4mz1A:
53.8
1jr1A-4mz1A:
37.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JR1_A_MOAA1332_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
5 / 11 ASP A 244
SER A 245
GLY A 296
THR A 303
GLY A 385
None
None
None
2F1  A 501 (-4.1A)
IMP  A 500 ( 3.3A)
1.15A 1jr1A-4mz1A:
53.8
1jr1A-4mz1A:
37.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JR1_A_MOAA1332_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
5 / 11 SER A 245
GLY A 296
CYH A 301
THR A 303
GLY A 385
None
None
IMP  A 500 ( 3.1A)
2F1  A 501 (-4.1A)
IMP  A 500 ( 3.3A)
0.70A 1jr1A-4mz1A:
53.8
1jr1A-4mz1A:
37.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JR1_B_MOAB1333_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
4 / 8 ASN A 273
GLY A 296
THR A 303
GLY A 385
IMP  A 500 ( 4.1A)
None
2F1  A 501 (-4.1A)
IMP  A 500 ( 3.3A)
0.30A 1jr1B-4mz1A:
53.6
1jr1B-4mz1A:
37.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JR1_B_MOAB1333_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
4 / 8 ASP A 244
ASN A 273
GLY A 296
THR A 303
None
IMP  A 500 ( 4.1A)
None
2F1  A 501 (-4.1A)
0.82A 1jr1B-4mz1A:
53.6
1jr1B-4mz1A:
37.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ME7_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
5 / 8 ASP A 244
SER A 245
ILE A 295
CYH A 301
GLY A 385
None
None
None
IMP  A 500 ( 3.1A)
IMP  A 500 ( 3.3A)
0.82A 1me7A-4mz1A:
50.2
1me7A-4mz1A:
29.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ME7_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
6 / 8 SER A 245
ASN A 273
ILE A 295
GLY A 296
CYH A 301
GLY A 385
None
IMP  A 500 ( 4.1A)
None
None
IMP  A 500 ( 3.1A)
IMP  A 500 ( 3.3A)
0.49A 1me7A-4mz1A:
50.2
1me7A-4mz1A:
29.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEH_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
5 / 10 ASP A 244
SER A 245
ILE A 295
GLY A 296
GLY A 385
None
None
None
None
IMP  A 500 ( 3.3A)
0.82A 1mehA-4mz1A:
48.4
1mehA-4mz1A:
29.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEH_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
5 / 10 SER A 245
ASN A 273
ILE A 295
GLY A 296
GLY A 385
None
IMP  A 500 ( 4.1A)
None
None
IMP  A 500 ( 3.3A)
0.51A 1mehA-4mz1A:
48.4
1mehA-4mz1A:
29.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEI_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
4 / 8 ASP A 244
SER A 245
ILE A 295
GLY A 385
None
None
None
IMP  A 500 ( 3.3A)
0.87A 1meiA-4mz1A:
49.7
1meiA-4mz1A:
29.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEI_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
4 / 8 SER A 245
ASN A 273
ILE A 295
GLY A 385
None
IMP  A 500 ( 4.1A)
None
IMP  A 500 ( 3.3A)
0.53A 1meiA-4mz1A:
49.7
1meiA-4mz1A:
29.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RR8_A_TTCA100_1
(DNA TOPOISOMERASE I)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
4 / 5 GLU A 465
LYS A 338
ASP A 342
THR A   9
None
1.23A 1rr8C-4mz1A:
undetectable
1rr8C-4mz1A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_2
(POL POLYPROTEIN)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
5 / 12 GLY A 442
ALA A 443
ASP A 445
ILE A 446
ALA A 344
None
0.80A 1sguB-4mz1A:
undetectable
1sguB-4mz1A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_A_STIA600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
4 / 6 LYS A 261
VAL A 242
VAL A 234
ILE A 260
None
0.99A 2hyyA-4mz1A:
undetectable
2hyyA-4mz1A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
4 / 6 LYS A 261
VAL A 242
VAL A 234
ILE A 260
None
1.00A 3ms9A-4mz1A:
undetectable
3ms9A-4mz1A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
4 / 6 LYS A 261
VAL A 242
VAL A 234
ILE A 260
None
1.00A 3mssA-4mz1A:
undetectable
3mssA-4mz1A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
4 / 7 LYS A 261
VAL A 242
VAL A 234
ILE A 260
None
1.02A 3mssB-4mz1A:
undetectable
3mssB-4mz1A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_C_STIC1_2
(TYROSINE-PROTEIN
KINASE ABL1)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
4 / 6 LYS A 261
VAL A 242
VAL A 234
ILE A 260
None
0.98A 3mssC-4mz1A:
undetectable
3mssC-4mz1A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_B_IL2B901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
5 / 12 LEU A 233
VAL A  82
THR A  52
ILE A 423
LEU A  66
None
0.98A 3sp9B-4mz1A:
undetectable
3sp9B-4mz1A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
4 / 6 ALA A 290
PRO A 330
LEU A  33
THR A  34
None
0.91A 4dtzA-4mz1A:
undetectable
4dtzA-4mz1A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DU2_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT B7)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
4 / 7 ALA A 290
PRO A 330
LEU A  33
THR A  34
None
0.86A 4du2B-4mz1A:
undetectable
4du2B-4mz1A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_A_CLQA303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
5 / 12 GLY A  65
ASN A  40
ILE A  44
VAL A 238
ILE A  37
None
1.14A 4fglA-4mz1A:
undetectable
4fglB-4mz1A:
undetectable
4fglA-4mz1A:
21.28
4fglB-4mz1A:
21.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FO4_A_MOAA502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
7 / 8 ASP A 244
SER A 245
ASN A 273
CYH A 301
THR A 303
MET A 384
GLY A 385
None
None
IMP  A 500 ( 4.1A)
IMP  A 500 ( 3.1A)
2F1  A 501 (-4.1A)
None
IMP  A 500 ( 3.3A)
0.37A 4fo4A-4mz1A:
55.9
4fo4A-4mz1A:
59.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FO4_B_MOAB502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
7 / 8 SER A 245
ASN A 273
GLY A 296
CYH A 301
THR A 303
MET A 384
GLY A 385
None
IMP  A 500 ( 4.1A)
None
IMP  A 500 ( 3.1A)
2F1  A 501 (-4.1A)
None
IMP  A 500 ( 3.3A)
0.31A 4fo4B-4mz1A:
51.3
4fo4B-4mz1A:
59.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FXS_A_MOAA702_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
7 / 9 SER A 245
ASN A 273
ILE A 295
GLY A 296
CYH A 301
THR A 303
ASP A 334
None
IMP  A 500 ( 4.1A)
None
None
IMP  A 500 ( 3.1A)
2F1  A 501 (-4.1A)
IMP  A 500 (-2.6A)
0.31A 4fxsA-4mz1A:
57.6
4fxsA-4mz1A:
48.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
5 / 12 GLY A 357
GLY A 335
ILE A 300
ILE A  44
ALA A  46
IMP  A 500 (-3.5A)
IMP  A 500 (-3.5A)
None
None
IMP  A 500 (-3.3A)
1.11A 4qtuB-4mz1A:
undetectable
4qtuB-4mz1A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_A_BQ1A1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
3 / 3 GLU A 323
ALA A 324
PHE A 327
None
0.57A 4v1fA-4mz1A:
undetectable
4v1fA-4mz1A:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_C_BQ1C1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
3 / 3 GLU A 323
ALA A 324
PHE A 327
None
0.62A 4v1fC-4mz1A:
undetectable
4v1fC-4mz1A:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_ACTA608_0
(SERUM ALBUMIN)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
3 / 3 LYS A  83
ARG A  84
HIS A  54
None
None
SO4  A 503 (-3.4A)
1.03A 4zbrA-4mz1A:
undetectable
4zbrA-4mz1A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
5 / 12 ILE A 274
GLY A 272
ASN A 273
ALA A 333
PHE A 327
None
None
IMP  A 500 ( 4.1A)
None
None
1.21A 5ih0A-4mz1A:
undetectable
5ih0A-4mz1A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
5 / 12 VAL A  22
ALA A 443
THR A  31
GLY A 432
LEU A 434
None
1.20A 5m54E-4mz1A:
2.4
5m54E-4mz1A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFP_A_8W5A804_2
(GLUCOCORTICOID
RECEPTOR)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
4 / 4 LEU A 431
MET A 438
ILE A 356
LEU A 347
None
1.42A 5nfpA-4mz1A:
undetectable
5nfpA-4mz1A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_2
(-)
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Campylobacter
jejuni)
5 / 12 GLY A 383
GLY A 385
GLY A 368
ASN A  72
ARG A 382
IMP  A 500 (-3.3A)
IMP  A 500 ( 3.3A)
None
None
None
1.00A 6gngB-4mz1A:
undetectable
6gngB-4mz1A:
22.56