SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mz9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA5_A_STRA301_1
(MINERALOCORTICOID
RECEPTOR)		 4mz9 SINGLE-STRANDED
DNA-BINDING PROTEIN
(Escherichia
coli) 		5 / 12 ASN A  31
LEU A  59
ALA A  30
SER A  68
LEU A  71
 None
 1.41A 2aa5A-4mz9A:
undetectable		 2aa5A-4mz9A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA5_B_STRB302_1
(MINERALOCORTICOID
RECEPTOR)		 4mz9 SINGLE-STRANDED
DNA-BINDING PROTEIN
(Escherichia
coli) 		5 / 12 ASN A  31
LEU A  59
ALA A  30
SER A  68
LEU A  71
 None
 1.41A 2aa5B-4mz9A:
undetectable		 2aa5B-4mz9A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)		 4mz9 SINGLE-STRANDED
DNA-BINDING PROTEIN
(Escherichia
coli) 		3 / 3 ASN A  31
GLU A  19
ARG A  21
 None
 1.02A 3wxoA-4mz9A:
undetectable		 3wxoA-4mz9A:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLT_A_8PRA505_1
(CYTOCHROME P450 2B4)		 4mz9 SINGLE-STRANDED
DNA-BINDING PROTEIN
(Escherichia
coli) 		4 / 8 ILE A  79
ILE A  32
ALA A  67
VAL A  77
 None
 0.81A 4jltA-4mz9A:
undetectable		 4jltA-4mz9A:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MV7_A_PPFA501_1
(BIOTIN CARBOXYLASE)		 4mz9 SINGLE-STRANDED
DNA-BINDING PROTEIN
(Escherichia
coli) 		4 / 7 ASN A  31
VAL A 102
GLU A 100
ARG A  84
 None
 0.94A 4mv7A-4mz9A:
undetectable		 4mv7A-4mz9A:
16.89