SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4mzl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDS_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 4mzl MYOSIN A TAIL DOMAIN
INTERACTING PROTEIN
(Plasmodium
falciparum) 		5 / 12 VAL A  72
LEU A 131
GLY A 103
TYR A 130
SER A  96
 None
 1.46A 1fdsA-4mzlA:
undetectable		 1fdsA-4mzlA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA193_1
(DIHYDROFOLATE
REDUCTASE)		 4mzl MYOSIN A TAIL DOMAIN
INTERACTING PROTEIN
(Plasmodium
falciparum) 		4 / 5 ASP A 139
LEU A 203
ILE A 145
PHE A 148
 None
 1.16A 3s3vA-4mzlA:
undetectable		 3s3vA-4mzlA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 4mzl MYOSIN A TAIL DOMAIN
INTERACTING PROTEIN
(Plasmodium
falciparum) 		3 / 3 THR A 170
ASP A 177
GLU A 179
 None
 0.83A 5fa8A-4mzlA:
undetectable		 5fa8A-4mzlA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 4mzl MYOSIN A TAIL DOMAIN
INTERACTING PROTEIN
(Plasmodium
falciparum) 		4 / 5 ARG A 100
ALA A  99
TYR A 130
ILE A  90
 None
 1.36A 6f6sA-4mzlA:
undetectable
6f6sB-4mzlA:
undetectable		 6f6sA-4mzlA:
17.69
6f6sB-4mzlA:
21.38