SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4n0r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_B_STRB2_1
(PROGESTERONE
RECEPTOR)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		5 / 12 LEU A 382
ASN A 452
LEU A 528
LEU A 419
CYH A 375
 None
 1.40A 1a28B-4n0rA:
undetectable		 1a28B-4n0rA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 6 TYR A 314
LEU A 342
VAL A 350
VAL A 355
 None
 1.14A 1dz4A-4n0rA:
undetectable		 1dz4A-4n0rA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 6 TYR A 314
LEU A 342
VAL A 350
VAL A 355
 None
 1.13A 1dz4B-4n0rA:
undetectable		 1dz4B-4n0rA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QW6_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 ARG A 165
VAL A 269
TRP A 270
 None
 1.25A 1qw6A-4n0rA:
undetectable		 1qw6A-4n0rA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QWC_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 ARG A 165
VAL A 269
TRP A 270
 None
 1.13A 1qwcA-4n0rA:
undetectable		 1qwcA-4n0rA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_A_SAMA500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 7 ASP A 220
ASN A 223
SER A 265
ARG A  75
 GOL  A 609 ( 3.9A)
None
None
None
 1.47A 1rqpB-4n0rA:
2.4		 1rqpB-4n0rA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_2
(TRANSTHYRETIN)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 8 GLU A 391
THR A 136
ALA A 138
VAL A 164
 None
 0.93A 1sn5C-4n0rA:
2.9		 1sn5C-4n0rA:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 5 TYR A 314
LEU A 342
VAL A 350
VAL A 355
 None
 1.12A 1t88B-4n0rA:
undetectable		 1t88B-4n0rA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 8 TYR A 314
LEU A 342
VAL A 350
VAL A 355
 None
 1.13A 1uyuB-4n0rA:
undetectable		 1uyuB-4n0rA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VAG_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 ARG A 165
VAL A 269
TRP A 270
 None
 1.19A 1vagA-4n0rA:
undetectable		 1vagA-4n0rA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVI_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 ARG A 165
VAL A 269
TRP A 270
 None
 1.17A 1zviA-4n0rA:
undetectable		 1zviA-4n0rA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 TRP A 365
THR A 137
TYR A 139
 UNL  A 601 ( 3.7A)
None
UNL  A 601 ( 4.7A)
 1.16A 2a3aA-4n0rA:
5.5		 2a3aA-4n0rA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 TRP A 365
GLU A 354
TYR A 357
 UNL  A 601 ( 3.7A)
UNL  A 601 (-2.8A)
UNL  A 601 ( 4.6A)
 1.25A 2a3aA-4n0rA:
5.5		 2a3aA-4n0rA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2434_1
(CHITINASE)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 TRP A 365
THR A 137
TYR A 139
 UNL  A 601 ( 3.7A)
None
UNL  A 601 ( 4.7A)
 1.21A 2a3aB-4n0rA:
5.6		 2a3aB-4n0rA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 TRP A 365
THR A 137
TYR A 139
 UNL  A 601 ( 3.7A)
None
UNL  A 601 ( 4.7A)
 1.19A 2a3bA-4n0rA:
5.4		 2a3bA-4n0rA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 8 ASP A 230
SER A 272
TYR A 317
HIS A 308
 None
 1.31A 2bteA-4n0rA:
undetectable		 2bteA-4n0rA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 8 ASP A 230
SER A 272
TYR A 317
HIS A 308
 None
 1.37A 2bteD-4n0rA:
2.5		 2bteD-4n0rA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1217_1
(LIPOPROTEIN LPPX)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 4 VAL A 355
LEU A 430
ILE A 423
LEU A 419
 None
 1.02A 2byoA-4n0rA:
undetectable		 2byoA-4n0rA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D06_B_ESTB305_1
(SULFOTRANSFERASE 1A1)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		5 / 10 HIS A 308
VAL A 333
TYR A 357
PHE A 376
MET A 373
 None
None
UNL  A 601 ( 4.6A)
None
None
 1.49A 2d06B-4n0rA:
undetectable		 2d06B-4n0rA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 6 TYR A 314
LEU A 342
VAL A 350
VAL A 355
 None
 1.06A 2feuA-4n0rA:
undetectable		 2feuA-4n0rA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_F_RBFF204_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 8 TYR A 279
TYR A 139
GLU A 354
TYR A 173
 None
UNL  A 601 ( 4.7A)
UNL  A 601 (-2.8A)
UNL  A 601 ( 4.2A)
 1.14A 2fl5E-4n0rA:
3.9
2fl5F-4n0rA:
3.0		 2fl5E-4n0rA:
16.02
2fl5F-4n0rA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 5 TYR A 314
LEU A 342
VAL A 350
VAL A 355
 None
 1.10A 2m56A-4n0rA:
undetectable		 2m56A-4n0rA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7L_A_TESA155_1
(ANDROGEN RECEPTOR)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		5 / 12 LEU A 378
ASN A 379
LEU A 381
GLY A 380
MET A 432
 None
 1.31A 2q7lA-4n0rA:
undetectable		 2q7lA-4n0rA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_A_LEUA1887_0
(AMINOACYL-TRNA
SYNTHETASE)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 8 ASP A 230
SER A 272
TYR A 317
HIS A 308
 None
 1.38A 2v0gA-4n0rA:
2.1		 2v0gA-4n0rA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_B_SAMB1299_1
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 7 ASP A 220
ASN A 223
SER A 265
ARG A  75
 GOL  A 609 ( 3.9A)
None
None
None
 1.48A 2v7uB-4n0rA:
undetectable		 2v7uB-4n0rA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 SER A 335
HIS A 121
ASP A 471
 None
NI  A 604 (-3.7A)
None
 0.81A 2wa2B-4n0rA:
undetectable		 2wa2B-4n0rA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		5 / 12 ILE A 423
GLY A 380
GLY A 384
PHE A 376
VAL A 387
 None
 1.14A 2yvlA-4n0rA:
undetectable		 2yvlA-4n0rA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 5 ILE A 377
HIS A 389
ARG A 420
GLY A 135
 None
 1.28A 3b9mA-4n0rA:
undetectable		 3b9mA-4n0rA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_B_1FLB500_1
(TRANSTHYRETIN)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 6 LYS A  99
SER A  50
THR A  52
VAL A  54
 None
 0.95A 3d2tB-4n0rA:
3.7		 3d2tB-4n0rA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 6 TYR A 314
LEU A 342
VAL A 350
VAL A 355
 None
 1.05A 3fwgA-4n0rA:
undetectable		 3fwgA-4n0rA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FZG_A_SAMA300_0
(16S RRNA METHYLASE)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		5 / 12 HIS A 389
SER A 412
GLY A 390
ILE A 400
LEU A 368
 None
 1.29A 3fzgA-4n0rA:
undetectable		 3fzgA-4n0rA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_4
(HIV-1 PROTEASE)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 ARG A 165
VAL A 117
THR A 323
 None
 0.78A 3k4vD-4n0rA:
undetectable		 3k4vD-4n0rA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 TYR A 279
LEU A 290
LYS A 289
 None
 0.60A 3sueD-4n0rA:
undetectable		 3sueD-4n0rA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_0
(MNMC2)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		5 / 12 GLY A 356
GLY A 366
LEU A 361
TYR A 363
GLU A 391
 None
 1.14A 3vywA-4n0rA:
undetectable		 3vywA-4n0rA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 6 TYR A 314
LEU A 342
VAL A 350
VAL A 355
 None
 1.08A 3wrhE-4n0rA:
undetectable		 3wrhE-4n0rA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 6 TYR A 314
LEU A 342
VAL A 350
VAL A 355
 None
 1.08A 3wrjE-4n0rA:
undetectable		 3wrjE-4n0rA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 HIS A 303
GLU A 228
ASN A 223
 None
 0.86A 4bupB-4n0rA:
undetectable		 4bupB-4n0rA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 6 TYR A 314
LEU A 342
VAL A 350
VAL A 355
 None
 1.04A 4ek1A-4n0rA:
undetectable		 4ek1A-4n0rA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 6 TYR A 314
LEU A 342
VAL A 350
VAL A 355
 None
 1.09A 4g3rA-4n0rA:
undetectable		 4g3rA-4n0rA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 6 TYR A 314
LEU A 342
VAL A 350
VAL A 355
 None
 1.10A 4g3rB-4n0rA:
undetectable		 4g3rB-4n0rA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 6 TYR A 314
LEU A 342
VAL A 350
VAL A 355
 None
 1.16A 4kkyX-4n0rA:
undetectable		 4kkyX-4n0rA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 5 TYR A 314
LEU A 342
VAL A 350
VAL A 355
 None
 1.09A 4l49A-4n0rA:
undetectable		 4l49A-4n0rA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 6 TYR A 314
LEU A 342
VAL A 350
VAL A 355
 None
 1.07A 4l4cA-4n0rA:
undetectable		 4l4cA-4n0rA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4D_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 8 TYR A 314
LEU A 342
VAL A 350
VAL A 355
 None
 1.11A 4l4dA-4n0rA:
undetectable		 4l4dA-4n0rA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 8 TYR A 314
LEU A 342
VAL A 350
VAL A 355
 None
 1.07A 4l4eA-4n0rA:
undetectable		 4l4eA-4n0rA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 8 TYR A 314
LEU A 342
VAL A 350
VAL A 355
 None
 1.06A 4l4fA-4n0rA:
undetectable		 4l4fA-4n0rA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 5 GLN A 404
THR A 136
HIS A 389
LEU A 408
 None
 1.25A 4lvcA-4n0rA:
2.6		 4lvcA-4n0rA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 5 GLN A 404
THR A 136
HIS A 389
LEU A 408
 None
 1.28A 4lvcC-4n0rA:
2.9		 4lvcC-4n0rA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_B_ASCB304_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 6 PHE A 123
HIS A 324
ILE A 351
ASN A 162
 None
 1.40A 4o7gB-4n0rA:
undetectable		 4o7gB-4n0rA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		5 / 12 LEU A 378
ASN A 379
GLY A 380
MET A 432
LEU A 450
 None
 1.31A 4p6xA-4n0rA:
undetectable		 4p6xA-4n0rA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		5 / 12 LEU A 378
ASN A 379
GLY A 380
MET A 432
LEU A 450
 None
 1.35A 4p6xE-4n0rA:
undetectable		 4p6xE-4n0rA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_A_032A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 5 ILE A 219
VAL A 269
PHE A  76
HIS A 214
 None
 1.32A 4rzvA-4n0rA:
undetectable		 4rzvA-4n0rA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UXQ_A_0LIA1752_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 7 VAL A 115
ILE A 351
ARG A 347
ILE A 385
 None
 0.86A 4uxqA-4n0rA:
undetectable		 4uxqA-4n0rA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA617_0
(SERUM ALBUMIN)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 TRP A 141
ARG A 218
LEU A 225
 None
 0.80A 5dbyA-4n0rA:
undetectable		 5dbyA-4n0rA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 GLU A 391
TRP A 402
ASN A 360
 None
UNL  A 601 ( 4.3A)
None
 1.02A 5dv4A-4n0rA:
undetectable		 5dv4A-4n0rA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 ARG A 165
VAL A 269
TRP A 270
 None
 1.05A 5fvoA-4n0rA:
undetectable		 5fvoA-4n0rA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_E_SC2E1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 VAL A 333
GLN A 328
CYH A 352
 None
NI  A 602 (-2.7A)
None
 0.51A 5icxA-4n0rA:
4.1
5icxE-4n0rA:
undetectable		 5icxA-4n0rA:
19.20
5icxE-4n0rA:
2.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_F_SC2F1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 VAL A 333
GLN A 328
CYH A 352
 None
NI  A 602 (-2.7A)
None
 0.72A 5icxC-4n0rA:
4.1
5icxF-4n0rA:
undetectable		 5icxC-4n0rA:
19.20
5icxF-4n0rA:
2.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 6 SER A 442
GLY A 380
ASN A 379
ILE A 423
 None
 0.91A 5j4nA-4n0rA:
undetectable		 5j4nA-4n0rA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 6 ALA A 264
VAL A 269
ASP A 299
TYR A 301
 None
 1.18A 5umd2-4n0rA:
undetectable
5umdF-4n0rA:
undetectable		 5umd2-4n0rA:
12.10
5umdF-4n0rA:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_A_SAMA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 HIS A 303
GLU A 228
ASN A 223
 None
 0.79A 5wbvA-4n0rA:
undetectable		 5wbvA-4n0rA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		3 / 3 HIS A 303
GLU A 228
ASN A 223
 None
 0.80A 5wbvB-4n0rA:
undetectable		 5wbvB-4n0rA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 8 TYR A 314
LEU A 342
VAL A 350
VAL A 355
 None
 1.11A 6cp4A-4n0rA:
undetectable		 6cp4A-4n0rA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_2
(-)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 5 GLN A 404
THR A 136
HIS A 389
LEU A 408
 None
 1.26A 6gbnA-4n0rA:
2.6		 6gbnA-4n0rA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_2
(-)		 4n0r PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
vulgatus) 		4 / 5 GLN A 404
THR A 136
HIS A 389
LEU A 408
 None
 1.27A 6gbnD-4n0rA:
2.3		 6gbnD-4n0rA:
22.16