SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4n11'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECLA600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4n11 GLUTAREDOXIN
(Plasmodium
falciparum) 		4 / 8 LEU A  69
THR A  70
GLY A  87
ILE A  53
 MPD  A 202 ( 4.2A)
None
MPO  A 201 (-3.5A)
None
 0.74A 3jusA-4n11A:
undetectable		 3jusA-4n11A:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4n11 GLUTAREDOXIN
(Plasmodium
falciparum) 		4 / 8 LEU A  69
THR A  70
GLY A  87
ILE A  53
 MPD  A 202 ( 4.2A)
None
MPO  A 201 (-3.5A)
None
 0.74A 3jusA-4n11A:
undetectable		 3jusA-4n11A:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y1D_D_DVAD5_0
(CYCLIC HEXAPEPTIDE
CYC[NDPOPPKID]
INTEGRASE)		 4n11 GLUTAREDOXIN
(Plasmodium
falciparum) 		3 / 3 GLU A  17
LYS A  82
ASN A  13
 MPD  A 202 (-3.8A)
None
MPD  A 202 (-4.1A)
 0.99A 4y1dA-4n11A:
undetectable
4y1dD-4n11A:
undetectable		 4y1dA-4n11A:
20.71
4y1dD-4n11A:
50.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4n11 GLUTAREDOXIN
(Plasmodium
falciparum) 		4 / 6 ARG A  77
ASP A  90
ARG A 103
ILE A  78
 None
 1.35A 5a06A-4n11A:
undetectable		 5a06A-4n11A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM0_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 4n11 GLUTAREDOXIN
(Plasmodium
falciparum) 		5 / 10 LEU A  39
ASP A  96
ILE A  78
PRO A  76
GLY A  87
 None
None
None
MPO  A 201 (-3.8A)
MPO  A 201 (-3.5A)
 1.24A 6dm0B-4n11A:
undetectable
6dm0C-4n11A:
undetectable		 6dm0B-4n11A:
17.82
6dm0C-4n11A:
17.82