SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4n13'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOB_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4n13 PHOSPHATE ABC
TRANSPORTER,
PERIPLASMIC
PHOSPHATE-BINDING
PROTEIN
(Borreliella
burgdorferi) 		5 / 12 PHE A  87
THR A 173
PHE A 156
ASN A 166
GLY A 167
 None
None
None
SO4  A 301 (-3.6A)
None
 1.23A 3aobC-4n13A:
undetectable		 3aobC-4n13A:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4n13 PHOSPHATE ABC
TRANSPORTER,
PERIPLASMIC
PHOSPHATE-BINDING
PROTEIN
(Borreliella
burgdorferi) 		5 / 12 PHE A  87
THR A 173
PHE A 156
ASN A 166
GLY A 167
 None
None
None
SO4  A 301 (-3.6A)
None
 1.25A 3aodC-4n13A:
undetectable		 3aodC-4n13A:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 4n13 PHOSPHATE ABC
TRANSPORTER,
PERIPLASMIC
PHOSPHATE-BINDING
PROTEIN
(Borreliella
burgdorferi) 		5 / 10 LEU A  85
ASN A 166
VAL A 169
GLY A 181
ILE A 139
 None
SO4  A 301 (-3.6A)
None
None
None
 1.44A 3bexC-4n13A:
undetectable
3bexD-4n13A:
undetectable		 3bexC-4n13A:
21.05
3bexD-4n13A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 4n13 PHOSPHATE ABC
TRANSPORTER,
PERIPLASMIC
PHOSPHATE-BINDING
PROTEIN
(Borreliella
burgdorferi) 		5 / 10 ASN A 166
VAL A 169
GLY A 181
ILE A 139
LEU A  85
 SO4  A 301 (-3.6A)
None
None
None
None
 1.44A 3bexE-4n13A:
undetectable
3bexF-4n13A:
undetectable		 3bexE-4n13A:
21.05
3bexF-4n13A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 4n13 PHOSPHATE ABC
TRANSPORTER,
PERIPLASMIC
PHOSPHATE-BINDING
PROTEIN
(Borreliella
burgdorferi) 		5 / 11 LEU A  85
ASN A 166
VAL A 169
GLY A 181
ILE A 139
 None
SO4  A 301 (-3.6A)
None
None
None
 1.42A 3bf1C-4n13A:
undetectable
3bf1D-4n13A:
undetectable		 3bf1C-4n13A:
21.05
3bf1D-4n13A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 4n13 PHOSPHATE ABC
TRANSPORTER,
PERIPLASMIC
PHOSPHATE-BINDING
PROTEIN
(Borreliella
burgdorferi) 		5 / 11 LEU A  85
ASN A 166
VAL A 169
GLY A 181
ILE A 139
 None
SO4  A 301 (-3.6A)
None
None
None
 1.42A 3bf1E-4n13A:
undetectable
3bf1F-4n13A:
undetectable		 3bf1E-4n13A:
21.05
3bf1F-4n13A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_1
(PROTEASE)		 4n13 PHOSPHATE ABC
TRANSPORTER,
PERIPLASMIC
PHOSPHATE-BINDING
PROTEIN
(Borreliella
burgdorferi) 		5 / 11 LEU A  22
ASP A  83
GLY A 258
ILE A 259
ILE A  21
 None
 1.06A 3el1A-4n13A:
undetectable		 3el1A-4n13A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ4_X_DXCX75_0
(CYTOCHROME C7)		 4n13 PHOSPHATE ABC
TRANSPORTER,
PERIPLASMIC
PHOSPHATE-BINDING
PROTEIN
(Borreliella
burgdorferi) 		5 / 9 ILE A 139
LEU A 107
LYS A 172
PHE A 126
GLY A 160
 None
None
None
EDO  A 305 ( 4.5A)
EDO  A 305 (-2.6A)
 1.30A 3sj4X-4n13A:
undetectable		 3sj4X-4n13A:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L78_A_ACTA1327_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 4n13 PHOSPHATE ABC
TRANSPORTER,
PERIPLASMIC
PHOSPHATE-BINDING
PROTEIN
(Borreliella
burgdorferi) 		4 / 4 VAL A 201
THR A  99
GLU A 100
GLU A 101
 None
 1.32A 4l78A-4n13A:
undetectable		 4l78A-4n13A:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLP_A_GAWA1501_0
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 4n13 PHOSPHATE ABC
TRANSPORTER,
PERIPLASMIC
PHOSPHATE-BINDING
PROTEIN
(Borreliella
burgdorferi) 		5 / 12 ASN A 227
ILE A 224
VAL A 235
THR A 236
ILE A 239
 None
 1.08A 6hlpA-4n13A:
undetectable		 6hlpA-4n13A:
19.28