SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4n1y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_A_STRA1_1
(PROGESTERONE
RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 LEU A 283
LEU A 286
MET A 321
ARG A 331
PHE A 462
 None
 0.45A 1a28A-4n1yA:
28.0		 1a28A-4n1yA:
29.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_B_STRB2_1
(PROGESTERONE
RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 LEU A 280
LEU A 283
LEU A 286
MET A 321
ARG A 331
 None
 0.41A 1a28B-4n1yA:
27.9		 1a28B-4n1yA:
29.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A52_A_ESTA1_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 10 ALA A 287
GLU A 290
LEU A 324
ARG A 331
ILE A 361
 None
 0.52A 1a52A-4n1yA:
28.4		 1a52A-4n1yA:
38.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A52_B_ESTB2_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 10 ALA A 287
GLU A 290
LEU A 324
ARG A 331
ILE A 361
 None
 0.54A 1a52B-4n1yA:
28.3		 1a52B-4n1yA:
38.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A52_B_ESTB2_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 10 ALA A 287
GLU A 290
LEU A 324
LEU A 325
LEU A 470
 None
 1.33A 1a52B-4n1yA:
28.3		 1a52B-4n1yA:
38.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ERE_A_ESTA600_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 9 ALA A 287
GLU A 290
LEU A 324
ARG A 331
ILE A 361
 None
 0.55A 1ereA-4n1yA:
30.3		 1ereA-4n1yA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ERE_B_ESTB600_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 9 ALA A 287
GLU A 290
LEU A 324
ARG A 331
ILE A 361
 None
 0.54A 1ereB-4n1yA:
30.3		 1ereB-4n1yA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ERE_C_ESTC600_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 9 ALA A 287
GLU A 290
LEU A 324
ARG A 331
ILE A 361
 None
 0.55A 1ereC-4n1yA:
30.3		 1ereC-4n1yA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ERE_D_ESTD600_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 9 ALA A 287
GLU A 290
LEU A 324
ARG A 331
ILE A 361
 None
 0.55A 1ereD-4n1yA:
30.4		 1ereD-4n1yA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ERR_A_RALA600_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 ALA A 287
GLU A 290
LEU A 291
TRP A 320
ARG A 331
 None
 0.57A 1errA-4n1yA:
27.5		 1errA-4n1yA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ERR_A_RALA600_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 ALA A 287
GLU A 290
TRP A 320
ARG A 331
MET A 358
 None
 0.96A 1errA-4n1yA:
27.5		 1errA-4n1yA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ERR_B_RALB600_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 ALA A 287
GLU A 290
LEU A 291
TRP A 320
LEU A 324
ARG A 331
 None
 0.50A 1errB-4n1yA:
26.9		 1errB-4n1yA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		8 / 11 LEU A 283
LEU A 286
ALA A 287
GLU A 290
LEU A 324
ARG A 331
MET A 358
ILE A 361
 None
 0.69A 1g50A-4n1yA:
31.0		 1g50A-4n1yA:
39.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1G50_B_ESTB1600_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 283
GLU A 290
LEU A 324
ARG A 331
ILE A 361
GLY A 447
 None
 0.71A 1g50B-4n1yA:
30.4		 1g50B-4n1yA:
39.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1G50_B_ESTB1600_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 283
LEU A 324
ARG A 331
MET A 358
ILE A 361
GLY A 447
 None
 0.75A 1g50B-4n1yA:
30.4		 1g50B-4n1yA:
39.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1G50_C_ESTC2600_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 11 LEU A 283
GLU A 290
LEU A 324
ARG A 331
ILE A 361
GLY A 447
 None
 0.72A 1g50C-4n1yA:
30.5		 1g50C-4n1yA:
39.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1G50_C_ESTC2600_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 11 LEU A 283
LEU A 324
ARG A 331
MET A 358
ILE A 361
GLY A 447
 None
 0.76A 1g50C-4n1yA:
30.5		 1g50C-4n1yA:
39.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		7 / 12 LEU A 283
LEU A 286
TRP A 320
MET A 321
MET A 358
LEU A 454
PHE A 462
 None
 0.96A 1gs4A-4n1yA:
29.1		 1gs4A-4n1yA:
28.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GWR_A_ESTA600_1
(OESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 10 LEU A 283
LEU A 286
ALA A 287
GLU A 290
LEU A 324
ARG A 331
 None
 0.45A 1gwrA-4n1yA:
30.9		 1gwrA-4n1yA:
39.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GWR_B_ESTB600_1
(OESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 9 LEU A 286
ALA A 287
GLU A 290
LEU A 324
ARG A 331
 None
 0.41A 1gwrB-4n1yA:
30.8		 1gwrB-4n1yA:
39.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M2Z_A_DEXA301_1
(GLUCOCORTICOID
RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 TRP A 320
MET A 321
ARG A 331
PHE A 462
LEU A 466
 None
 0.77A 1m2zA-4n1yA:
27.8		 1m2zA-4n1yA:
24.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PCG_A_ESTA1_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 10 LEU A 283
ALA A 287
GLU A 290
LEU A 324
ARG A 331
ILE A 361
 None
 0.59A 1pcgA-4n1yA:
30.8		 1pcgA-4n1yA:
39.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PCG_B_ESTB2_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 10 LEU A 283
ALA A 287
GLU A 290
LEU A 324
ARG A 331
 None
 0.37A 1pcgB-4n1yA:
31.0		 1pcgB-4n1yA:
39.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QKN_A_RALA600_1
(ESTROGEN RECEPTOR
BETA)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		7 / 12 LEU A 283
ALA A 287
GLU A 290
MET A 321
LEU A 324
ARG A 331
GLY A 447
 None
 0.60A 1qknA-4n1yA:
27.0		 1qknA-4n1yA:
39.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QKN_A_RALA600_1
(ESTROGEN RECEPTOR
BETA)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 LEU A 283
MET A 321
ARG A 331
ILE A 361
GLY A 447
 None
 0.83A 1qknA-4n1yA:
27.0		 1qknA-4n1yA:
39.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QKT_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 10 LEU A 283
ALA A 287
GLU A 290
LEU A 324
ARG A 331
MET A 358
 None
 0.67A 1qktA-4n1yA:
26.7		 1qktA-4n1yA:
38.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QKU_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 10 ALA A 287
GLU A 290
LEU A 324
ARG A 331
ILE A 361
 None
 0.60A 1qkuA-4n1yA:
30.6		 1qkuA-4n1yA:
38.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QKU_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 10 ALA A 287
LEU A 324
ARG A 331
MET A 358
ILE A 361
 None
 0.69A 1qkuA-4n1yA:
30.6		 1qkuA-4n1yA:
38.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QKU_B_ESTB600_1
(ESTRADIOL RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 10 ALA A 287
GLU A 290
LEU A 324
ARG A 331
ILE A 361
 None
 0.60A 1qkuB-4n1yA:
30.7		 1qkuB-4n1yA:
38.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QKU_B_ESTB600_1
(ESTRADIOL RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 10 ALA A 287
LEU A 324
ARG A 331
MET A 358
ILE A 361
 None
 0.70A 1qkuB-4n1yA:
30.7		 1qkuB-4n1yA:
38.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QKU_C_ESTC600_1
(ESTRADIOL RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 10 ALA A 287
GLU A 290
LEU A 324
ARG A 331
ILE A 361
 None
 0.61A 1qkuC-4n1yA:
30.7		 1qkuC-4n1yA:
38.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QKU_C_ESTC600_1
(ESTRADIOL RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 10 ALA A 287
LEU A 324
ARG A 331
MET A 358
ILE A 361
 None
 0.69A 1qkuC-4n1yA:
30.7		 1qkuC-4n1yA:
38.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_A_DESA459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		7 / 12 LEU A 280
LEU A 283
ALA A 287
GLU A 290
MET A 321
LEU A 324
ARG A 331
 None
 0.48A 1s9pA-4n1yA:
28.2		 1s9pA-4n1yA:
27.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		7 / 12 LEU A 280
LEU A 286
ALA A 287
GLU A 290
MET A 321
LEU A 324
ARG A 331
 None
 0.52A 1s9pB-4n1yA:
28.8		 1s9pB-4n1yA:
27.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_C_DESC500_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		8 / 12 LEU A 280
LEU A 283
LEU A 286
ALA A 287
GLU A 290
MET A 321
LEU A 324
ARG A 331
 None
 0.48A 1s9pC-4n1yA:
28.5		 1s9pC-4n1yA:
27.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_D_DESD600_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		7 / 12 LEU A 280
LEU A 283
ALA A 287
GLU A 290
MET A 321
LEU A 324
ARG A 331
 None
 0.46A 1s9pD-4n1yA:
30.0		 1s9pD-4n1yA:
27.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_A_CHDA459_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		4 / 6 LEU A 291
VAL A 292
ILE A 295
TRP A 320
 None
 0.83A 1s9qA-4n1yA:
28.3		 1s9qA-4n1yA:
27.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_B_CHDB500_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		4 / 4 LEU A 291
VAL A 292
ILE A 295
TRP A 320
 None
 0.80A 1s9qB-4n1yA:
27.9		 1s9qB-4n1yA:
27.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_1
(MINERALOCORTICOID
RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 280
LEU A 286
ALA A 287
MET A 321
ARG A 331
MET A 358
 None
 0.68A 1ya3A-4n1yA:
28.3		 1ya3A-4n1yA:
27.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_1
(MINERALOCORTICOID
RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 LEU A 280
ALA A 287
MET A 321
ARG A 331
MET A 358
 None
 0.93A 1ya3B-4n1yA:
27.7		 1ya3B-4n1yA:
27.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_C_STRC3001_1
(MINERALOCORTICOID
RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		7 / 12 LEU A 280
LEU A 283
LEU A 286
ALA A 287
MET A 321
ARG A 331
MET A 358
 None
 0.79A 1ya3C-4n1yA:
27.5		 1ya3C-4n1yA:
27.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 280
LEU A 283
LEU A 286
MET A 321
ARG A 331
PHE A 462
 None
 0.58A 1zucB-4n1yA:
27.5		 1zucB-4n1yA:
29.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 LEU A 324
LEU A 323
GLN A 386
LEU A 261
LEU A 286
 None
 1.28A 1zucB-4n1yA:
27.5		 1zucB-4n1yA:
29.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA5_A_STRA301_1
(MINERALOCORTICOID
RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 LEU A 286
ALA A 287
MET A 321
ARG A 331
MET A 358
 None
 0.52A 2aa5A-4n1yA:
28.4		 2aa5A-4n1yA:
27.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA5_B_STRB302_1
(MINERALOCORTICOID
RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 280
LEU A 286
ALA A 287
MET A 321
ARG A 331
MET A 358
 None
 0.71A 2aa5B-4n1yA:
28.1		 2aa5B-4n1yA:
27.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 283
LEU A 286
ALA A 287
MET A 321
ARG A 331
MET A 358
 None
 0.48A 2aa6A-4n1yA:
28.2		 2aa6A-4n1yA:
28.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_B_STRB402_1
(MINERALOCORTICOID
RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 LEU A 286
ALA A 287
MET A 321
ARG A 331
MET A 358
 None
 0.54A 2aa6B-4n1yA:
28.1		 2aa6B-4n1yA:
28.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_A_SNLA502_1
(MINERALOCORTICOID
RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		7 / 12 LEU A 280
ALA A 287
MET A 321
ARG A 331
PHE A 342
MET A 358
PHE A 462
 None
 0.67A 2ab2A-4n1yA:
28.2		 2ab2A-4n1yA:
28.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_B_SNLB503_1
(MINERALOCORTICOID
RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		7 / 12 LEU A 280
ALA A 287
MET A 321
ARG A 331
PHE A 342
MET A 358
PHE A 462
 None
 0.67A 2ab2B-4n1yA:
28.1		 2ab2B-4n1yA:
28.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AM9_A_TESA1000_1
(ANDROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 LEU A 286
TRP A 320
MET A 321
ARG A 331
MET A 358
 None
 0.80A 2am9A-4n1yA:
28.8		 2am9A-4n1yA:
29.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2J7X_A_ESTA1454_1
(ESTROGEN RECEPTOR
BETA)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 286
GLU A 290
LEU A 324
ARG A 331
ILE A 361
GLY A 444
 None
 1.41A 2j7xA-4n1yA:
30.7		 2j7xA-4n1yA:
39.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2J7X_A_ESTA1454_1
(ESTROGEN RECEPTOR
BETA)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		7 / 12 LEU A 286
GLU A 290
MET A 321
LEU A 324
ARG A 331
ILE A 361
GLY A 447
 None
 0.54A 2j7xA-4n1yA:
30.7		 2j7xA-4n1yA:
39.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 ALA A 287
GLU A 290
LEU A 291
TRP A 320
LEU A 324
ARG A 331
 None
 0.42A 2jfaA-4n1yA:
27.5		 2jfaA-4n1yA:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 ALA A 287
GLU A 290
LEU A 324
ARG A 331
MET A 358
 None
 0.80A 2jfaA-4n1yA:
27.5		 2jfaA-4n1yA:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 ALA A 287
GLU A 290
LEU A 291
ARG A 331
GLY A 444
 None
 0.96A 2jfaB-4n1yA:
26.6		 2jfaB-4n1yA:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		7 / 12 ALA A 287
GLU A 290
LEU A 291
TRP A 320
LEU A 324
ARG A 331
GLY A 447
 None
 0.66A 2jfaB-4n1yA:
26.6		 2jfaB-4n1yA:
35.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 ALA A 287
GLU A 290
TRP A 320
LEU A 324
ARG A 331
MET A 358
 None
 0.77A 2jfaB-4n1yA:
26.6		 2jfaB-4n1yA:
35.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		4 / 8 MET A 407
SER A 410
ALA A 255
LEU A 256
 None
 1.09A 2o01A-4n1yA:
undetectable		 2o01A-4n1yA:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 280
LEU A 286
MET A 321
ARG A 331
MET A 358
PHE A 462
 None
 0.76A 2oaxA-4n1yA:
28.1		 2oaxA-4n1yA:
26.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		4 / 5 LEU A 283
ALA A 287
TRP A 320
LEU A 324
 None
 0.57A 2oaxA-4n1yA:
28.1		 2oaxA-4n1yA:
26.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 280
LEU A 286
ALA A 287
MET A 321
ARG A 331
PHE A 462
 None
 0.53A 2oaxB-4n1yA:
28.1		 2oaxB-4n1yA:
26.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_C_SNLC3001_1
(MINERALOCORTICOID
RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		7 / 12 LEU A 280
ALA A 287
TRP A 320
MET A 321
ARG A 331
MET A 358
PHE A 462
 None
 0.81A 2oaxC-4n1yA:
27.3		 2oaxC-4n1yA:
26.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_1
(MINERALOCORTICOID
RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		8 / 12 LEU A 280
LEU A 286
ALA A 287
TRP A 320
MET A 321
ARG A 331
MET A 358
PHE A 462
 None
 0.72A 2oaxD-4n1yA:
28.2		 2oaxD-4n1yA:
26.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_E_SNLE5001_1
(MINERALOCORTICOID
RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 280
LEU A 286
ALA A 287
ARG A 331
MET A 358
PHE A 462
 None
 0.89A 2oaxE-4n1yA:
27.6		 2oaxE-4n1yA:
26.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_E_SNLE5001_1
(MINERALOCORTICOID
RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 280
LEU A 286
ALA A 287
MET A 321
ARG A 331
PHE A 462
 None
 0.63A 2oaxE-4n1yA:
27.6		 2oaxE-4n1yA:
26.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 286
ALA A 287
TRP A 320
MET A 321
ARG A 331
PHE A 462
 None
 0.60A 2oaxF-4n1yA:
27.8		 2oaxF-4n1yA:
26.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OCF_A_ESTA596_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 10 LEU A 283
ALA A 287
GLU A 290
LEU A 324
ARG A 331
 None
 0.63A 2ocfA-4n1yA:
31.9		 2ocfA-4n1yA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OCF_A_ESTA596_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 10 LEU A 283
ALA A 287
LEU A 324
ARG A 331
MET A 358
 None
 0.84A 2ocfA-4n1yA:
31.9		 2ocfA-4n1yA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OUZ_A_C3DA999_0
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 LEU A 283
LEU A 291
LEU A 324
ILE A 361
GLY A 447
 None
 0.68A 2ouzA-4n1yA:
26.3		 2ouzA-4n1yA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OUZ_A_C3DA999_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 6 ALA A 287
GLU A 290
TRP A 320
ARG A 331
MET A 358
 None
 1.01A 2ouzA-4n1yA:
26.3		 2ouzA-4n1yA:
38.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_1
(ANDROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 283
LEU A 286
ARG A 331
MET A 358
LEU A 454
PHE A 462
 None
 0.79A 2oz7A-4n1yA:
28.7		 2oz7A-4n1yA:
28.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7I_A_TESA205_1
(ANDROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 LEU A 283
LEU A 286
MET A 321
ARG A 331
MET A 358
 None
 0.63A 2q7iA-4n1yA:
29.0		 2q7iA-4n1yA:
28.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7J_A_TESA203_1
(ANDROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 280
LEU A 286
TRP A 320
MET A 321
ARG A 331
MET A 358
 None
 0.80A 2q7jA-4n1yA:
28.9		 2q7jA-4n1yA:
28.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 LEU A 283
LEU A 286
MET A 321
ARG A 331
MET A 358
 None
 0.60A 2q7kA-4n1yA:
29.2		 2q7kA-4n1yA:
28.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7L_A_TESA155_1
(ANDROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 283
LEU A 286
TRP A 320
MET A 321
ARG A 331
MET A 358
 None
 0.76A 2q7lA-4n1yA:
28.9		 2q7lA-4n1yA:
28.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 ALA A 287
GLU A 290
LEU A 291
TRP A 320
LEU A 324
ARG A 331
 None
 0.45A 2qxsA-4n1yA:
27.1		 2qxsA-4n1yA:
38.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 ALA A 287
TRP A 320
LEU A 324
ARG A 331
ILE A 361
 None
 0.67A 2qxsA-4n1yA:
27.1		 2qxsA-4n1yA:
38.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QXS_B_RALB600_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 ALA A 287
GLU A 290
LEU A 291
TRP A 320
LEU A 324
ARG A 331
 None
 0.51A 2qxsB-4n1yA:
26.9		 2qxsB-4n1yA:
38.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QXS_B_RALB600_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 ALA A 287
GLU A 290
TRP A 320
LEU A 324
ARG A 331
ILE A 361
 None
 0.71A 2qxsB-4n1yA:
26.9		 2qxsB-4n1yA:
38.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_1
(PROGESTERONE
RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 LEU A 280
LEU A 286
TRP A 320
MET A 321
ARG A 331
 None
 0.65A 2w8yA-4n1yA:
27.8		 2w8yA-4n1yA:
29.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_B_NDRB1000_0
(PROGESTERONE
RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 LEU A 280
LEU A 283
LEU A 286
MET A 321
ARG A 331
 None
 0.47A 2w8yB-4n1yA:
27.8		 2w8yB-4n1yA:
29.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YHD_A_TESA1920_1
(ANDROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 LEU A 280
LEU A 286
MET A 321
ARG A 331
MET A 358
 None
 0.70A 2yhdA-4n1yA:
28.3		 2yhdA-4n1yA:
28.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YJA_B_ESTB1550_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 ALA A 287
GLU A 290
LEU A 324
ARG A 331
ILE A 361
GLY A 444
 None
 1.38A 2yjaB-4n1yA:
30.7		 2yjaB-4n1yA:
38.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YJA_B_ESTB1550_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 ALA A 287
GLU A 290
LEU A 324
ARG A 331
ILE A 361
GLY A 447
 None
 0.57A 2yjaB-4n1yA:
30.7		 2yjaB-4n1yA:
38.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YJA_B_ESTB1550_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 ALA A 287
GLU A 290
LEU A 324
ARG A 331
MET A 358
ILE A 361
 None
 0.70A 2yjaB-4n1yA:
30.7		 2yjaB-4n1yA:
38.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLO_A_TESA1920_1
(ANDROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 LEU A 283
LEU A 286
MET A 321
ARG A 331
PHE A 462
 None
 0.67A 2yloA-4n1yA:
28.3		 2yloA-4n1yA:
28.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 LEU A 280
LEU A 283
LEU A 286
MET A 321
ARG A 331
 None
 0.48A 3d90A-4n1yA:
27.5		 3d90A-4n1yA:
29.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 LEU A 280
LEU A 283
LEU A 286
MET A 321
ARG A 331
 None
 0.65A 3d90B-4n1yA:
27.5		 3d90B-4n1yA:
29.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ERD_A_DESA600_1
(ESTROGEN RECEPTOR
ALPHA)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 283
ALA A 287
GLU A 290
LEU A 324
ARG A 331
MET A 358
 None
 0.70A 3erdA-4n1yA:
30.8		 3erdA-4n1yA:
38.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ERD_B_DESB800_1
(ESTROGEN RECEPTOR
ALPHA)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 10 ALA A 287
GLU A 290
LEU A 324
ARG A 331
MET A 358
 None
 0.72A 3erdB-4n1yA:
31.5		 3erdB-4n1yA:
38.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_A_DEXA247_1
(GLUCOCORTICOID
RECEPTOR 2)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 LEU A 283
TRP A 320
MET A 321
ARG A 331
VAL A 460
 None
 0.86A 3gn8A-4n1yA:
27.7		 3gn8A-4n1yA:
26.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_B_DEXB247_1
(GLUCOCORTICOID
RECEPTOR 2)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 283
TRP A 320
MET A 321
ARG A 331
VAL A 460
PHE A 462
 None
 0.80A 3gn8B-4n1yA:
27.7		 3gn8B-4n1yA:
26.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HM1_A_J3ZA2_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 283
ALA A 287
GLU A 290
LEU A 324
ARG A 331
MET A 358
 None
 0.73A 3hm1A-4n1yA:
32.1		 3hm1A-4n1yA:
39.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HM1_B_J3ZB1_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 11 LEU A 283
LEU A 286
GLU A 290
ARG A 331
MET A 358
GLY A 447
 None
 0.65A 3hm1B-4n1yA:
31.6		 3hm1B-4n1yA:
39.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HM1_B_J3ZB1_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 11 LEU A 283
LEU A 286
MET A 321
MET A 358
LEU A 454
 None
 1.36A 3hm1B-4n1yA:
31.6		 3hm1B-4n1yA:
39.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OLL_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 10 LEU A 283
LEU A 286
GLU A 290
MET A 321
ARG A 331
 None
 0.48A 3ollA-4n1yA:
29.3		 3ollA-4n1yA:
38.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OLL_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 9 LEU A 283
LEU A 286
GLU A 290
MET A 321
ARG A 331
 None
 0.49A 3ollB-4n1yA:
29.3		 3ollB-4n1yA:
38.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OLS_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		8 / 12 LEU A 283
LEU A 286
ALA A 287
GLU A 290
MET A 321
LEU A 324
ARG A 331
GLY A 447
 None
 0.44A 3olsA-4n1yA:
31.7		 3olsA-4n1yA:
38.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OLS_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 286
ALA A 287
GLU A 290
LEU A 324
ARG A 331
GLY A 444
 None
 1.17A 3olsA-4n1yA:
31.7		 3olsA-4n1yA:
38.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OLS_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 283
ALA A 287
GLU A 290
MET A 321
LEU A 324
ARG A 331
 None
 0.38A 3olsB-4n1yA:
30.8		 3olsB-4n1yA:
38.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q95_A_ESLA700_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 ALA A 287
GLU A 290
LEU A 324
ARG A 331
GLY A 444
 None
 0.99A 3q95A-4n1yA:
31.5		 3q95A-4n1yA:
38.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q95_A_ESLA700_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		7 / 12 LEU A 283
ALA A 287
GLU A 290
LEU A 324
ARG A 331
ILE A 361
GLY A 447
 None
 0.69A 3q95A-4n1yA:
31.5		 3q95A-4n1yA:
38.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q95_B_ESLB700_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		8 / 12 LEU A 283
LEU A 286
ALA A 287
GLU A 290
LEU A 324
ARG A 331
ILE A 361
GLY A 447
 None
 0.65A 3q95B-4n1yA:
30.7		 3q95B-4n1yA:
38.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q95_B_ESLB700_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 286
ALA A 287
GLU A 290
ARG A 331
ILE A 361
GLY A 444
 None
 1.46A 3q95B-4n1yA:
30.7		 3q95B-4n1yA:
38.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UUD_A_ESTA600_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 11 LEU A 283
ALA A 287
GLU A 290
LEU A 324
ARG A 331
GLY A 447
 None
 0.57A 3uudA-4n1yA:
31.6		 3uudA-4n1yA:
38.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UUD_B_ESTB600_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 10 ALA A 287
GLU A 290
LEU A 324
ARG A 331
MET A 358
 None
 0.75A 3uudB-4n1yA:
31.6		 3uudB-4n1yA:
38.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 280
ALA A 287
MET A 321
ARG A 331
MET A 358
PHE A 462
 None
 0.72A 3vhuA-4n1yA:
28.9		 3vhuA-4n1yA:
26.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_TESA1000_1
(ANDROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 LEU A 280
LEU A 283
LEU A 286
MET A 321
ARG A 331
 None
 0.54A 3zqtA-4n1yA:
28.7		 3zqtA-4n1yA:
28.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FN9_A_STRA301_1
(STEROID RECEPTOR 2)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		7 / 12 LEU A 280
LEU A 283
LEU A 286
ALA A 287
MET A 321
ARG A 331
MET A 358
 None
 0.75A 4fn9A-4n1yA:
29.3		 4fn9A-4n1yA:
31.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FN9_B_STRB301_1
(STEROID RECEPTOR 2)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		8 / 12 LEU A 280
LEU A 283
LEU A 286
ALA A 287
TRP A 320
MET A 321
ARG A 331
MET A 358
 None
 0.79A 4fn9B-4n1yA:
29.5		 4fn9B-4n1yA:
31.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J24_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		7 / 12 LEU A 283
LEU A 286
GLU A 290
MET A 321
LEU A 324
ARG A 331
ILE A 361
 None
 0.62A 4j24A-4n1yA:
31.2		 4j24A-4n1yA:
38.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J24_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		7 / 12 LEU A 283
LEU A 286
GLU A 290
MET A 321
LEU A 324
ARG A 331
ILE A 361
 None
 0.60A 4j24B-4n1yA:
31.0		 4j24B-4n1yA:
38.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J24_C_ESTC600_1
(ESTROGEN RECEPTOR
BETA)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 286
GLU A 290
MET A 321
LEU A 324
ARG A 331
ILE A 361
 None
 0.64A 4j24C-4n1yA:
31.1		 4j24C-4n1yA:
38.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J24_D_ESTD600_1
(ESTROGEN RECEPTOR
BETA)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 286
ALA A 287
GLU A 290
MET A 321
ARG A 331
ILE A 361
 None
 0.57A 4j24D-4n1yA:
30.9		 4j24D-4n1yA:
38.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J26_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 LEU A 286
GLU A 290
LEU A 324
ARG A 331
GLY A 444
 None
 1.24A 4j26A-4n1yA:
31.2		 4j26A-4n1yA:
38.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J26_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		7 / 12 LEU A 286
GLU A 290
MET A 321
LEU A 324
ARG A 331
ILE A 361
GLY A 447
 None
 0.58A 4j26A-4n1yA:
31.2		 4j26A-4n1yA:
38.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J26_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 286
GLU A 290
MET A 321
LEU A 324
ARG A 331
ILE A 361
 None
 0.59A 4j26B-4n1yA:
31.3		 4j26B-4n1yA:
38.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_1
(SEPIAPTERIN
REDUCTASE)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 LEU A 283
PHE A 451
ALA A 443
MET A 321
LEU A 325
 None
 1.31A 4j7xB-4n1yA:
undetectable		 4j7xB-4n1yA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 11 MET A 407
SER A 410
ALA A 255
LEU A 256
LEU A 465
 None
 1.06A 4kt0A-4n1yA:
undetectable
4kt0J-4n1yA:
undetectable		 4kt0A-4n1yA:
14.30
4kt0J-4n1yA:
10.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LTW_A_486A302_1
(ANCESTRAL STEROID
RECEPTOR 2)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 LEU A 291
GLN A 312
ILE A 316
GLU A 468
ALA A 472
 None
 0.79A 4ltwA-4n1yA:
29.6		 4ltwA-4n1yA:
31.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LTW_A_486A302_1
(ANCESTRAL STEROID
RECEPTOR 2)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 LEU A 291
LEU A 309
GLN A 312
GLU A 468
ALA A 472
 None
 0.67A 4ltwA-4n1yA:
29.6		 4ltwA-4n1yA:
31.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LTW_A_486A302_1
(ANCESTRAL STEROID
RECEPTOR 2)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 LEU A 291
LYS A 299
GLN A 312
ILE A 316
ALA A 472
 None
 0.88A 4ltwA-4n1yA:
29.6		 4ltwA-4n1yA:
31.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LTW_A_486A302_1
(ANCESTRAL STEROID
RECEPTOR 2)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 LEU A 291
LYS A 299
LEU A 309
GLN A 312
ALA A 472
 None
 0.83A 4ltwA-4n1yA:
29.6		 4ltwA-4n1yA:
31.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LTW_A_STRA301_1
(ANCESTRAL STEROID
RECEPTOR 2)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		7 / 12 LEU A 280
LEU A 283
LEU A 286
ALA A 287
MET A 321
ARG A 331
MET A 358
 None
 0.71A 4ltwA-4n1yA:
29.6		 4ltwA-4n1yA:
31.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LTW_A_STRA301_2
(ANCESTRAL STEROID
RECEPTOR 2)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		4 / 8 TRP A 320
PHE A 450
VAL A 460
PHE A 462
 None
 0.60A 4ltwA-4n1yA:
29.6		 4ltwA-4n1yA:
31.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PXM_A_ESTA2000_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		7 / 12 LEU A 283
LEU A 286
ALA A 287
GLU A 290
LEU A 324
ARG A 331
GLY A 447
 None
 0.52A 4pxmA-4n1yA:
31.5		 4pxmA-4n1yA:
38.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PXM_A_ESTA2000_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 286
ALA A 287
GLU A 290
LEU A 324
ARG A 331
GLY A 444
 None
 1.11A 4pxmA-4n1yA:
31.5		 4pxmA-4n1yA:
38.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PXM_B_ESTB2000_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		7 / 11 LEU A 286
ALA A 287
GLU A 290
LEU A 324
ARG A 331
ILE A 361
GLY A 444
 None
 1.34A 4pxmB-4n1yA:
30.7		 4pxmB-4n1yA:
38.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PXM_B_ESTB2000_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		7 / 11 LEU A 286
ALA A 287
GLU A 290
LEU A 324
ARG A 331
ILE A 361
GLY A 447
 None
 0.57A 4pxmB-4n1yA:
30.7		 4pxmB-4n1yA:
38.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDA_A_DEXA1985_1
(MINERALOCORTICOID
RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 280
ALA A 287
MET A 321
ARG A 331
MET A 358
PHE A 462
 None
 0.80A 4udaA-4n1yA:
28.9		 4udaA-4n1yA:
27.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_1
(GLUCOCORTICOID
RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 LEU A 283
TRP A 320
MET A 321
ARG A 331
PHE A 462
 None
 0.73A 4udcA-4n1yA:
27.9		 4udcA-4n1yA:
24.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XI3_A_29SA601_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 ALA A 287
GLU A 290
LEU A 291
TRP A 320
ARG A 331
 None
 0.73A 4xi3A-4n1yA:
26.4		 4xi3A-4n1yA:
38.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 ALA A 287
LEU A 291
TRP A 320
LEU A 324
ARG A 331
 None
 0.57A 4xi3B-4n1yA:
27.3		 4xi3B-4n1yA:
38.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 ALA A 287
TRP A 320
LEU A 324
ARG A 331
ILE A 361
GLY A 447
 None
 0.71A 4xi3B-4n1yA:
27.3		 4xi3B-4n1yA:
38.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 286
ALA A 287
LEU A 291
TRP A 320
LEU A 324
ARG A 331
 None
 0.57A 4xi3C-4n1yA:
27.0		 4xi3C-4n1yA:
38.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 LEU A 286
ALA A 287
LEU A 324
ARG A 331
MET A 358
 None
 0.91A 4xi3C-4n1yA:
27.0		 4xi3C-4n1yA:
38.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 286
ALA A 287
TRP A 320
LEU A 324
ARG A 331
GLY A 447
 None
 0.71A 4xi3C-4n1yA:
27.0		 4xi3C-4n1yA:
38.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XI3_D_29SD601_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 ALA A 287
GLU A 290
LEU A 291
TRP A 320
LEU A 324
ARG A 331
 None
 0.71A 4xi3D-4n1yA:
26.7		 4xi3D-4n1yA:
38.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XI3_D_29SD601_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 ALA A 287
GLU A 290
LEU A 324
LEU A 325
LEU A 470
 None
 1.27A 4xi3D-4n1yA:
26.7		 4xi3D-4n1yA:
38.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZN7_A_DESA601_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		7 / 12 LEU A 283
ALA A 287
GLU A 290
LEU A 324
ARG A 331
MET A 358
LEU A 466
 None
 0.69A 4zn7A-4n1yA:
32.0		 4zn7A-4n1yA:
38.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZN7_B_DESB600_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 11 LEU A 283
ALA A 287
GLU A 290
LEU A 324
ARG A 331
MET A 358
 None
 0.61A 4zn7B-4n1yA:
32.4		 4zn7B-4n1yA:
38.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DX3_A_ESTA601_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 10 LEU A 286
ALA A 287
GLU A 290
LEU A 324
ARG A 331
GLY A 444
 None
 1.09A 5dx3A-4n1yA:
32.0		 5dx3A-4n1yA:
38.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DX3_A_ESTA601_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 10 LEU A 286
ALA A 287
GLU A 290
LEU A 324
ARG A 331
GLY A 447
 None
 0.51A 5dx3A-4n1yA:
32.0		 5dx3A-4n1yA:
38.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DX3_B_ESTB1000_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 9 ALA A 287
GLU A 290
LEU A 324
ARG A 331
MET A 358
 None
 0.71A 5dx3B-4n1yA:
31.6		 5dx3B-4n1yA:
38.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DXB_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 10 ALA A 287
GLU A 290
LEU A 324
ARG A 331
GLY A 444
 None
 1.02A 5dxbA-4n1yA:
32.2		 5dxbA-4n1yA:
38.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DXB_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 10 LEU A 283
ALA A 287
GLU A 290
LEU A 324
ARG A 331
GLY A 447
 None
 0.49A 5dxbA-4n1yA:
32.2		 5dxbA-4n1yA:
38.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DXB_B_ESTB601_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 11 ALA A 287
GLU A 290
LEU A 324
ARG A 331
ILE A 361
GLY A 444
 None
 1.38A 5dxbB-4n1yA:
31.3		 5dxbB-4n1yA:
38.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DXB_B_ESTB601_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 11 ALA A 287
GLU A 290
LEU A 324
ARG A 331
ILE A 361
GLY A 447
 None
 0.55A 5dxbB-4n1yA:
31.3		 5dxbB-4n1yA:
38.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DXE_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		4 / 8 LEU A 283
GLU A 290
LEU A 324
ARG A 331
 None
 0.37A 5dxeA-4n1yA:
32.2		 5dxeA-4n1yA:
38.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DXE_B_ESTB1000_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 10 LEU A 283
ALA A 287
GLU A 290
LEU A 324
ARG A 331
 None
 0.35A 5dxeB-4n1yA:
31.6		 5dxeB-4n1yA:
38.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DXG_B_ESTB601_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 11 LEU A 286
ALA A 287
GLU A 290
LEU A 324
ARG A 331
GLY A 444
 None
 1.12A 5dxgB-4n1yA:
31.4		 5dxgB-4n1yA:
38.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DXG_B_ESTB601_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 11 LEU A 286
ALA A 287
GLU A 290
LEU A 324
ARG A 331
GLY A 447
 None
 0.52A 5dxgB-4n1yA:
31.4		 5dxgB-4n1yA:
38.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GS4_A_ESTA603_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 286
ALA A 287
GLU A 290
ARG A 331
ILE A 361
GLY A 444
 None
 1.37A 5gs4A-4n1yA:
29.9		 5gs4A-4n1yA:
39.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GS4_A_ESTA603_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 286
ALA A 287
GLU A 290
ARG A 331
ILE A 361
GLY A 447
 None
 0.60A 5gs4A-4n1yA:
29.9		 5gs4A-4n1yA:
39.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GS4_A_ESTA603_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 286
ALA A 287
GLU A 290
ARG A 331
MET A 358
ILE A 361
 None
 0.85A 5gs4A-4n1yA:
29.9		 5gs4A-4n1yA:
39.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GTR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 286
ALA A 287
GLU A 290
LEU A 324
ARG A 331
GLY A 444
 None
 1.07A 5gtrA-4n1yA:
30.4		 5gtrA-4n1yA:
39.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GTR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		7 / 12 LEU A 286
ALA A 287
GLU A 290
LEU A 324
ARG A 331
ILE A 361
GLY A 447
 None
 0.60A 5gtrA-4n1yA:
30.4		 5gtrA-4n1yA:
39.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GTR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		7 / 12 LEU A 286
ALA A 287
GLU A 290
LEU A 324
ARG A 331
MET A 358
ILE A 361
 None
 0.71A 5gtrA-4n1yA:
30.4		 5gtrA-4n1yA:
39.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HYR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 10 LEU A 283
ALA A 287
GLU A 290
LEU A 324
ARG A 331
 None
 0.37A 5hyrA-4n1yA:
32.0		 5hyrA-4n1yA:
38.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HYR_B_ESTB601_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 11 LEU A 286
ALA A 287
GLU A 290
LEU A 324
ARG A 331
MET A 358
 None
 0.68A 5hyrB-4n1yA:
31.0		 5hyrB-4n1yA:
38.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 12 GLY A 444
MET A 321
LEU A 324
ALA A 287
PHE A 342
 None
 1.33A 5kc4E-4n1yA:
undetectable		 5kc4E-4n1yA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_0
(MINERALOCORTICOID
RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 280
LEU A 283
ALA A 287
TRP A 320
MET A 321
MET A 358
 None
 0.81A 5mwyA-4n1yA:
28.5		 5mwyA-4n1yA:
25.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TOA_A_ESTA601_1
(ESTROGEN RECEPTOR
BETA)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		7 / 12 LEU A 283
LEU A 286
ALA A 287
GLU A 290
MET A 321
LEU A 324
ARG A 331
 None
 0.42A 5toaA-4n1yA:
28.6		 5toaA-4n1yA:
38.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TOA_B_ESTB601_1
(ESTROGEN RECEPTOR
BETA)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 12 LEU A 286
GLU A 290
MET A 321
LEU A 324
ARG A 331
ILE A 361
 None
 0.70A 5toaB-4n1yA:
28.3		 5toaB-4n1yA:
38.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGD_A_ESTA601_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 9 ALA A 287
GLU A 290
LEU A 324
LEU A 325
LEU A 470
 None
 1.39A 5wgdA-4n1yA:
31.8		 5wgdA-4n1yA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 9 ALA A 287
GLU A 290
LEU A 324
ARG A 331
GLY A 444
 None
 1.06A 5wgqA-4n1yA:
31.6		 5wgqA-4n1yA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 9 ALA A 287
GLU A 290
LEU A 324
ARG A 331
MET A 358
GLY A 447
 None
 0.69A 5wgqA-4n1yA:
31.6		 5wgqA-4n1yA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_B_ESTB601_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 10 ALA A 287
GLU A 290
LEU A 324
ARG A 331
MET A 358
 None
 0.71A 5wgqB-4n1yA:
31.5		 5wgqB-4n1yA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_B_ESTB601_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 10 ALA A 287
GLU A 290
LEU A 324
LEU A 325
LEU A 470
 None
 1.39A 5wgqB-4n1yA:
31.5		 5wgqB-4n1yA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		4 / 8 LEU A 283
GLU A 290
LEU A 324
ARG A 331
 None
 0.42A 6cbzA-4n1yA:
31.8		 6cbzA-4n1yA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_B_ESTB602_1
(ESTROGEN RECEPTOR)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		6 / 10 LEU A 286
ALA A 287
GLU A 290
LEU A 324
ARG A 331
ILE A 361
 None
 0.53A 6cbzB-4n1yA:
31.1		 6cbzB-4n1yA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_A_PQNA2001_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 4n1y ESTROGEN RECEPTOR
(Crassostrea
gigas) 		5 / 10 MET A 407
SER A 410
ALA A 255
LEU A 256
LEU A 465
 None
 1.01A 6hqbA-4n1yA:
2.5
6hqbJ-4n1yA:
undetectable		 6hqbA-4n1yA:
18.52
6hqbJ-4n1yA:
10.21