SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4n30'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 4n30 PROTEIN DISULFIDE
ISOMERASE
(Pseudomonas
aeruginosa) 		5 / 12 THR A 193
THR A 185
ARG A 195
LEU A 186
LEU A 215
 None
 1.41A 1eiiA-4n30A:
undetectable		 1eiiA-4n30A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 4n30 PROTEIN DISULFIDE
ISOMERASE
(Pseudomonas
aeruginosa) 		4 / 7 ARG A 107
ALA A 106
ILE A 172
PRO A  94
 None
 1.09A 1oniA-4n30A:
undetectable
1oniB-4n30A:
undetectable		 1oniA-4n30A:
17.89
1oniB-4n30A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 4n30 PROTEIN DISULFIDE
ISOMERASE
(Pseudomonas
aeruginosa) 		4 / 6 ARG A 107
ALA A 106
ILE A 172
PRO A  94
 None
 1.09A 1oniB-4n30A:
undetectable
1oniC-4n30A:
undetectable		 1oniB-4n30A:
17.89
1oniC-4n30A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_H_BEZH515_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 4n30 PROTEIN DISULFIDE
ISOMERASE
(Pseudomonas
aeruginosa) 		4 / 6 ARG A 107
ALA A 106
ILE A 172
PRO A  94
 None
 1.02A 1oniH-4n30A:
undetectable
1oniI-4n30A:
undetectable		 1oniH-4n30A:
17.89
1oniI-4n30A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 4n30 PROTEIN DISULFIDE
ISOMERASE
(Pseudomonas
aeruginosa) 		4 / 7 ILE A 172
PRO A  94
ARG A 107
ALA A 106
 None
 1.05A 1oniG-4n30A:
undetectable
1oniI-4n30A:
undetectable		 1oniG-4n30A:
17.89
1oniI-4n30A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1160_1
(ALLERGEN ARG R 1)		 4n30 PROTEIN DISULFIDE
ISOMERASE
(Pseudomonas
aeruginosa) 		4 / 7 SER A 177
VAL A 187
TYR A  61
ILE A 174
 None
 1.07A 2x45B-4n30A:
undetectable		 2x45B-4n30A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1160_1
(ALLERGEN ARG R 1)		 4n30 PROTEIN DISULFIDE
ISOMERASE
(Pseudomonas
aeruginosa) 		4 / 7 SER A 177
VAL A 187
TYR A  61
ILE A 174
 None
 1.04A 2x45C-4n30A:
undetectable		 2x45C-4n30A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BU1_A_HSMA301_1
(LIPOCALIN)		 4n30 PROTEIN DISULFIDE
ISOMERASE
(Pseudomonas
aeruginosa) 		4 / 7 SER A 177
VAL A 187
TYR A  61
ILE A 174
 None
 1.05A 3bu1A-4n30A:
undetectable		 3bu1A-4n30A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_1
(PCZA361.24)		 4n30 PROTEIN DISULFIDE
ISOMERASE
(Pseudomonas
aeruginosa) 		3 / 3 ARG A  78
GLU A  60
ASP A  63
 None
 0.92A 3g2oA-4n30A:
undetectable		 3g2oA-4n30A:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_A_ROFA901_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 4n30 PROTEIN DISULFIDE
ISOMERASE
(Pseudomonas
aeruginosa) 		3 / 3 ASP A 145
LEU A 144
GLN A 115
 None
 0.73A 3g4lA-4n30A:
undetectable		 3g4lA-4n30A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP3_B_AICB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4n30 PROTEIN DISULFIDE
ISOMERASE
(Pseudomonas
aeruginosa) 		3 / 3 ALA A 158
ARG A 107
LYS A 169
 None
 1.04A 3kp3B-4n30A:
undetectable		 3kp3B-4n30A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 4n30 PROTEIN DISULFIDE
ISOMERASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 108
GLY A 138
ILE A 128
ALA A 101
HIS A 104
 None
 1.28A 3uj7A-4n30A:
undetectable		 3uj7A-4n30A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3A_A_TACA222_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 4n30 PROTEIN DISULFIDE
ISOMERASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 154
PRO A 147
GLN A 151
GLN A 131
SER A 123
 None
 1.24A 4b3aA-4n30A:
undetectable		 4b3aA-4n30A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_2
(CDL2.3B)		 4n30 PROTEIN DISULFIDE
ISOMERASE
(Pseudomonas
aeruginosa) 		5 / 9 PRO A 184
VAL A  80
LEU A  88
ILE A  58
LEU A  64
 None
 1.21A 5iepA-4n30A:
undetectable		 5iepA-4n30A:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 4n30 PROTEIN DISULFIDE
ISOMERASE
(Pseudomonas
aeruginosa) 		5 / 12 GLU A 100
LEU A  64
GLY A 138
LEU A 144
ALA A 127
 None
 1.34A 5kbwA-4n30A:
undetectable		 5kbwA-4n30A:
21.98