SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4n31'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Z_A_COCA301_2
(CHIMERA OF IG KAPPA
CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION
CHIMERA OF IG
GAMMA-1 CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION)		 4n31 SIPA
(Streptococcus
pyogenes) 		4 / 5 TYR A 116
GLU A 145
TYR A 142
ASP A  48
 None
 1.25A 1i7zB-4n31A:
undetectable		 1i7zB-4n31A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6K_A_ADNA699_1
(CHLORINASE)		 4n31 SIPA
(Streptococcus
pyogenes) 		4 / 7 PHE A 127
TYR A 119
PRO A 120
THR A 118
 None
 1.42A 2q6kA-4n31A:
undetectable		 2q6kA-4n31A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APX_A_Z80A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 4n31 SIPA
(Streptococcus
pyogenes) 		5 / 12 PHE A 127
LEU A 103
ALA A  89
PHE A 137
TYR A 129
 None
 1.45A 3apxA-4n31A:
undetectable		 3apxA-4n31A:
20.71