SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4n3o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4n3o PUTATIVE
D-GLYCERO-D-MANNO-HE
PTOSE 7-PHOSPHATE
KINASE
(Campylobacter
jejuni) 		4 / 5 GLU A 173
TYR A  31
TYR A  28
PHE A 171
 None
 1.23A 1dfoB-4n3oA:
undetectable		 1dfoB-4n3oA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4n3o PUTATIVE
D-GLYCERO-D-MANNO-HE
PTOSE 7-PHOSPHATE
KINASE
(Campylobacter
jejuni) 		4 / 5 GLU A 173
TYR A  31
TYR A  28
PHE A 171
 None
 1.23A 1dfoD-4n3oA:
undetectable		 1dfoD-4n3oA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_F_ACTF3008_0
(BETA-CARBONIC
ANHYDRASE)		 4n3o PUTATIVE
D-GLYCERO-D-MANNO-HE
PTOSE 7-PHOSPHATE
KINASE
(Campylobacter
jejuni) 		4 / 8 PHE A 174
VAL A  32
GLY A  17
GLY A  16
 None
 0.91A 1ekjE-4n3oA:
undetectable
1ekjF-4n3oA:
undetectable		 1ekjE-4n3oA:
22.42
1ekjF-4n3oA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 4n3o PUTATIVE
D-GLYCERO-D-MANNO-HE
PTOSE 7-PHOSPHATE
KINASE
(Campylobacter
jejuni) 		4 / 8 ALA A 287
PHE A 303
VAL A 305
VAL A 200
 None
 0.61A 1epbB-4n3oA:
undetectable		 1epbB-4n3oA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_2
(TRANSTHYRETIN)		 4n3o PUTATIVE
D-GLYCERO-D-MANNO-HE
PTOSE 7-PHOSPHATE
KINASE
(Campylobacter
jejuni) 		4 / 7 LEU A 101
THR A   8
LEU A  45
VAL A 334
 None
 0.86A 1ictD-4n3oA:
undetectable		 1ictD-4n3oA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5R_A_RBFA859_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4n3o PUTATIVE
D-GLYCERO-D-MANNO-HE
PTOSE 7-PHOSPHATE
KINASE
(Campylobacter
jejuni) 		5 / 11 LEU A 195
ALA A 287
GLY A 286
TYR A 288
PHE A 249
 None
 1.36A 1l5rA-4n3oA:
undetectable		 1l5rA-4n3oA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RV7_B_AB1B1001_1
(PROTEASE)		 4n3o PUTATIVE
D-GLYCERO-D-MANNO-HE
PTOSE 7-PHOSPHATE
KINASE
(Campylobacter
jejuni) 		5 / 11 ALA A 141
THR A   8
PRO A   9
VAL A 121
VAL A 180
 None
 1.06A 1rv7A-4n3oA:
undetectable
1rv7B-4n3oA:
undetectable		 1rv7A-4n3oA:
14.85
1rv7B-4n3oA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_FFOA505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4n3o PUTATIVE
D-GLYCERO-D-MANNO-HE
PTOSE 7-PHOSPHATE
KINASE
(Campylobacter
jejuni) 		4 / 6 GLU A 173
TYR A  31
TYR A  28
PHE A 171
 None
 1.25A 2vmyA-4n3oA:
undetectable		 2vmyA-4n3oA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_B_FFOB505_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4n3o PUTATIVE
D-GLYCERO-D-MANNO-HE
PTOSE 7-PHOSPHATE
KINASE
(Campylobacter
jejuni) 		4 / 4 GLU A 173
TYR A  31
TYR A  28
PHE A 171
 None
 1.27A 2vmyB-4n3oA:
undetectable		 2vmyB-4n3oA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_A_VDNA1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4n3o PUTATIVE
D-GLYCERO-D-MANNO-HE
PTOSE 7-PHOSPHATE
KINASE
(Campylobacter
jejuni) 		5 / 12 ILE A  84
LEU A 143
ALA A 141
ILE A 140
ILE A  41
 None
 1.13A 3b2rA-4n3oA:
undetectable		 3b2rA-4n3oA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMF_A_SAMA388_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 4n3o PUTATIVE
D-GLYCERO-D-MANNO-HE
PTOSE 7-PHOSPHATE
KINASE
(Campylobacter
jejuni) 		5 / 12 PHE A 300
GLY A 110
GLY A 298
ALA A 295
ASP A  59
 None
 0.93A 3dmfA-4n3oA:
undetectable		 3dmfA-4n3oA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC0_A_MIYA1204_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS B FROM
TRANSPOSON TN1 0)		 4n3o PUTATIVE
D-GLYCERO-D-MANNO-HE
PTOSE 7-PHOSPHATE
KINASE
(Campylobacter
jejuni) 		5 / 12 PHE A 166
ASN A 170
GLN A 161
THR A 165
LEU A 113
 None
 1.47A 4ac0A-4n3oA:
undetectable		 4ac0A-4n3oA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDA_A_RLTA403_1
(MARINER MOS1
TRANSPOSASE)		 4n3o PUTATIVE
D-GLYCERO-D-MANNO-HE
PTOSE 7-PHOSPHATE
KINASE
(Campylobacter
jejuni) 		4 / 6 ASP A 284
ASN A 285
ALA A 282
TYR A 279
 None
 1.15A 4mdaA-4n3oA:
undetectable		 4mdaA-4n3oA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 4n3o PUTATIVE
D-GLYCERO-D-MANNO-HE
PTOSE 7-PHOSPHATE
KINASE
(Campylobacter
jejuni) 		5 / 12 GLY A 296
ALA A 295
GLY A 298
GLY A 299
PHE A 203
 None
 0.81A 4o33A-4n3oA:
undetectable		 4o33A-4n3oA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 4n3o PUTATIVE
D-GLYCERO-D-MANNO-HE
PTOSE 7-PHOSPHATE
KINASE
(Campylobacter
jejuni) 		5 / 12 GLY A 296
GLY A 298
GLY A 299
PHE A 203
GLY A 110
 None
 0.81A 4o33A-4n3oA:
undetectable		 4o33A-4n3oA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 4n3o PUTATIVE
D-GLYCERO-D-MANNO-HE
PTOSE 7-PHOSPHATE
KINASE
(Campylobacter
jejuni) 		5 / 12 GLY A 296
GLY A 298
GLY A 299
PHE A 203
GLY A 110
 None
 0.91A 4o3fA-4n3oA:
undetectable		 4o3fA-4n3oA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 4n3o PUTATIVE
D-GLYCERO-D-MANNO-HE
PTOSE 7-PHOSPHATE
KINASE
(Campylobacter
jejuni) 		5 / 10 ALA A 164
GLU A 137
ALA A  35
GLY A 168
THR A 330
 None
 1.21A 5lf3H-4n3oA:
undetectable
5lf3I-4n3oA:
undetectable		 5lf3H-4n3oA:
23.05
5lf3I-4n3oA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 4n3o PUTATIVE
D-GLYCERO-D-MANNO-HE
PTOSE 7-PHOSPHATE
KINASE
(Campylobacter
jejuni) 		5 / 10 ALA A 164
GLU A 137
ALA A  35
GLY A 168
THR A 330
 None
 1.22A 5lf3V-4n3oA:
undetectable
5lf3W-4n3oA:
undetectable		 5lf3V-4n3oA:
23.05
5lf3W-4n3oA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_B_STRB502_1
(CYTOCHROME P450
CYP260A1)		 4n3o PUTATIVE
D-GLYCERO-D-MANNO-HE
PTOSE 7-PHOSPHATE
KINASE
(Campylobacter
jejuni) 		4 / 6 LEU A  45
ALA A 126
LEU A  97
THR A  93
 None
 0.95A 6f88B-4n3oA:
undetectable		 6f88B-4n3oA:
12.05