SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4n4g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR4_X_PNTX101_0
(PROTEIN S100-B)		 4n4g ZINC FINGER MYND
DOMAIN-CONTAINING
PROTEIN 11
(Mus
musculus) 		3 / 3 CYH A 274
HIS A 353
PHE A 273
 None
 1.20A 3cr4X-4n4gA:
undetectable		 3cr4X-4n4gA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4n4g ZINC FINGER MYND
DOMAIN-CONTAINING
PROTEIN 11
(Mus
musculus) 		5 / 12 ASP A 307
ALA A 286
PHE A 310
LEU A 264
PHE A 273
 None
 1.30A 4iaqA-4n4gA:
3.4		 4iaqA-4n4gA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA305_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 4n4g ZINC FINGER MYND
DOMAIN-CONTAINING
PROTEIN 11
(Mus
musculus) 		4 / 6 LEU A 255
LEU A 252
GLU A 254
ILE A 165
 None
 0.96A 4ww7A-4n4gA:
undetectable		 4ww7A-4n4gA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 4n4g ZINC FINGER MYND
DOMAIN-CONTAINING
PROTEIN 11
(Mus
musculus) 		5 / 12 LEU A 244
ILE A 229
HIS A 225
LEU A 191
GLY A 232
 None
 1.12A 5d4uB-4n4gA:
undetectable		 5d4uB-4n4gA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 4n4g ZINC FINGER MYND
DOMAIN-CONTAINING
PROTEIN 11
(Mus
musculus) 		4 / 8 ARG A 309
LYS A 297
VAL A 332
ARG A 358
 None
 1.10A 6fbvD-4n4gA:
undetectable		 6fbvD-4n4gA:
11.05