SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4n4r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTB_A_PZQA901_0
(GLUTATHIONE
S-TRANSFERASE)		 4n4r LPS-ASSEMBLY PROTEIN
LPTD
LPS-ASSEMBLY
LIPOPROTEIN LPTE
(Salmonella
enterica;
Salmonella
enterica) 		3 / 3 GLN A 655
TYR B 123
ARG B 124
 None
 0.80A 1gtbA-4n4rA:
undetectable		 1gtbA-4n4rA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4n4r LPS-ASSEMBLY PROTEIN
LPTD
LPS-ASSEMBLY
LIPOPROTEIN LPTE
(Salmonella
enterica;
Salmonella
enterica) 		5 / 12 GLY B  45
VAL A 320
ALA B  50
SER B  40
LEU B  75
 None
 1.23A 1kiaD-4n4rB:
undetectable		 1kiaD-4n4rB:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4n4r LPS-ASSEMBLY PROTEIN
LPTD
(Salmonella
enterica) 		4 / 8 SER A 387
GLN A 378
PHE A 377
ASN A 419
 None
 1.18A 1p6kB-4n4rA:
undetectable		 1p6kB-4n4rA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBC_A_BHAA396_0
(P-HYDROXYBENZOATE
HYDROXYLASE)		 4n4r LPS-ASSEMBLY
LIPOPROTEIN LPTE
(Salmonella
enterica) 		5 / 10 GLY B  45
LEU B  77
LEU B  38
SER B  40
ALA B  50
 None
 0.96A 1pbcA-4n4rB:
undetectable		 1pbcA-4n4rB:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4n4r LPS-ASSEMBLY PROTEIN
LPTD
(Salmonella
enterica) 		4 / 8 SER A 387
GLN A 357
PHE A 377
ASN A 419
 None
 1.31A 1rs7B-4n4rA:
undetectable		 1rs7B-4n4rA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4n4r LPS-ASSEMBLY PROTEIN
LPTD
(Salmonella
enterica) 		4 / 8 SER A 387
GLN A 378
PHE A 377
ASN A 419
 None
 1.18A 1rs7B-4n4rA:
undetectable		 1rs7B-4n4rA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_1
(CES1 PROTEIN)		 4n4r LPS-ASSEMBLY
LIPOPROTEIN LPTE
(Salmonella
enterica) 		5 / 12 GLY B  41
VAL B  51
SER B 107
LEU B  38
LEU B 155
 None
 1.06A 1ya4C-4n4rB:
undetectable		 1ya4C-4n4rB:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_B_CFXB1002_2
(BETA-LACTAMASE
CTX-M-9)		 4n4r LPS-ASSEMBLY
LIPOPROTEIN LPTE
LPS-ASSEMBLY PROTEIN
LPTD
(Salmonella
enterica) 		4 / 5 TYR A 706
PRO A 714
THR B  86
THR A 351
 None
 1.05A 1ymxB-4n4rA:
undetectable		 1ymxB-4n4rA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4n4r LPS-ASSEMBLY PROTEIN
LPTD
(Salmonella
enterica) 		4 / 8 SER A 387
GLN A 378
PHE A 377
ASN A 419
 None
 1.17A 1zzqB-4n4rA:
undetectable		 1zzqB-4n4rA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4n4r LPS-ASSEMBLY PROTEIN
LPTD
(Salmonella
enterica) 		4 / 8 SER A 387
GLN A 357
PHE A 377
ASN A 419
 None
 1.33A 1zzuB-4n4rA:
undetectable		 1zzuB-4n4rA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4n4r LPS-ASSEMBLY PROTEIN
LPTD
(Salmonella
enterica) 		4 / 8 SER A 387
GLN A 378
PHE A 377
ASN A 419
 None
 1.18A 1zzuB-4n4rA:
undetectable		 1zzuB-4n4rA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_B_TRPB603_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4n4r LPS-ASSEMBLY PROTEIN
LPTD
(Salmonella
enterica) 		5 / 12 TYR A 521
THR A 592
GLY A 593
GLY A 526
GLU A 477
 None
 1.32A 2azxB-4n4rA:
undetectable		 2azxB-4n4rA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B9E_A_SAMA1201_0
(NOL1/NOP2/SUN DOMAIN
FAMILY, MEMBER 5
ISOFORM 2)		 4n4r LPS-ASSEMBLY PROTEIN
LPTD
LPS-ASSEMBLY
LIPOPROTEIN LPTE
(Salmonella
enterica;
Salmonella
enterica) 		5 / 12 PRO A 781
LEU A 738
ASP A 716
PHE B  90
SER A 350
 None
 1.42A 2b9eA-4n4rA:
undetectable		 2b9eA-4n4rA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLJ_A_SPMA1303_1
(POTASSIUM CHANNEL)		 4n4r LPS-ASSEMBLY
LIPOPROTEIN LPTE
LPS-ASSEMBLY PROTEIN
LPTD
(Salmonella
enterica) 		3 / 3 ARG A 326
ARG B  49
PRO B  46
 None
 1.10A 2wljA-4n4rA:
undetectable		 2wljA-4n4rA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_A_ADNA1301_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 4n4r LPS-ASSEMBLY PROTEIN
LPTD
(Salmonella
enterica) 		4 / 7 ARG A 576
GLU A 575
ALA A 572
ALA A 573
 None
 1.08A 2zgwA-4n4rA:
undetectable		 2zgwA-4n4rA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZTH_A_SAMA305_1
(CATECHOL
O-METHYLTRANSFERASE)		 4n4r LPS-ASSEMBLY PROTEIN
LPTD
(Salmonella
enterica) 		3 / 3 SER A 692
GLU A 773
ASP A 651
 None
 0.43A 2zthA-4n4rA:
undetectable		 2zthA-4n4rA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZVJ_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 4n4r LPS-ASSEMBLY PROTEIN
LPTD
(Salmonella
enterica) 		4 / 6 GLU A 426
SER A 389
GLN A 376
ASP A 422
 None
 1.14A 2zvjA-4n4rA:
undetectable		 2zvjA-4n4rA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_1
(UNCHARACTERIZED
PROTEIN PH0793)		 4n4r LPS-ASSEMBLY PROTEIN
LPTD
(Salmonella
enterica) 		3 / 3 MET A 271
GLU A 242
ASP A 751
 None
 1.10A 3a25A-4n4rA:
undetectable		 3a25A-4n4rA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWM_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 4n4r LPS-ASSEMBLY PROTEIN
LPTD
(Salmonella
enterica) 		3 / 3 SER A 692
GLU A 773
ASP A 651
 None
 0.60A 3bwmA-4n4rA:
undetectable		 3bwmA-4n4rA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWY_A_SAMA301_1
(COMT PROTEIN)		 4n4r LPS-ASSEMBLY PROTEIN
LPTD
(Salmonella
enterica) 		3 / 3 SER A 692
GLU A 773
ASP A 651
 None
 0.54A 3bwyA-4n4rA:
undetectable		 3bwyA-4n4rA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_A_D16A530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4n4r LPS-ASSEMBLY
LIPOPROTEIN LPTE
LPS-ASSEMBLY PROTEIN
LPTD
(Salmonella
enterica) 		5 / 12 ALA B  87
ILE A 684
ASN A 682
ASP B  92
GLY B  93
 None
 1.22A 3nrrA-4n4rB:
undetectable		 3nrrA-4n4rB:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4n4r LPS-ASSEMBLY
LIPOPROTEIN LPTE
(Salmonella
enterica) 		5 / 12 ALA B  50
ASP B 149
ALA B 151
THR B 120
VAL B  80
 None
 1.03A 3rukA-4n4rB:
undetectable		 3rukA-4n4rB:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4n4r LPS-ASSEMBLY
LIPOPROTEIN LPTE
LPS-ASSEMBLY PROTEIN
LPTD
(Salmonella
enterica) 		4 / 8 ASP A 613
ASP A 490
ASN A 540
GLU B 153
 None
 0.95A 4gkhC-4n4rA:
undetectable
4gkhK-4n4rA:
undetectable		 4gkhC-4n4rA:
16.46
4gkhK-4n4rA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4n4r LPS-ASSEMBLY
LIPOPROTEIN LPTE
LPS-ASSEMBLY PROTEIN
LPTD
(Salmonella
enterica) 		4 / 8 ASP A 613
ASP A 490
ASN A 540
GLU B 153
 None
 0.96A 4gkiE-4n4rA:
undetectable
4gkiG-4n4rA:
undetectable		 4gkiE-4n4rA:
16.46
4gkiG-4n4rA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 4n4r LPS-ASSEMBLY PROTEIN
LPTD
(Salmonella
enterica) 		4 / 5 TYR A 665
GLN A 536
SER A 537
ASP A 594
 None
 1.28A 4qtuB-4n4rA:
undetectable		 4qtuB-4n4rA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_A_AERA601_1
(CYP17A1 PROTEIN)		 4n4r LPS-ASSEMBLY
LIPOPROTEIN LPTE
(Salmonella
enterica) 		5 / 9 ALA B  50
ASP B 149
ALA B 151
THR B 120
VAL B  80
 None
 0.94A 4r1zA-4n4rB:
undetectable		 4r1zA-4n4rB:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_B_Y70B151_1
(CEREBLON ISOFORM 4)		 4n4r LPS-ASSEMBLY
LIPOPROTEIN LPTE
LPS-ASSEMBLY PROTEIN
LPTD
(Salmonella
enterica) 		4 / 8 ASN B 129
PRO B 130
MET B 132
TYR A 665
 None
 1.49A 4v2zB-4n4rB:
undetectable		 4v2zB-4n4rB:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 4n4r LPS-ASSEMBLY PROTEIN
LPTD
(Salmonella
enterica) 		3 / 3 SER A 692
GLU A 773
ASP A 651
 None
 0.61A 4xudA-4n4rA:
undetectable		 4xudA-4n4rA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_1
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 4n4r LPS-ASSEMBLY PROTEIN
LPTD
LPS-ASSEMBLY
LIPOPROTEIN LPTE
(Salmonella
enterica;
Salmonella
enterica) 		3 / 3 SER A 441
GLU B 153
GLU A 575
 None
 0.79A 4ymgB-4n4rA:
undetectable		 4ymgB-4n4rA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_CE9A402_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 4n4r LPS-ASSEMBLY PROTEIN
LPTD
LPS-ASSEMBLY
LIPOPROTEIN LPTE
(Salmonella
enterica;
Salmonella
enterica) 		5 / 12 ALA A 638
ALA A 661
PHE B 127
LEU A 670
THR A 669
 None
 1.21A 5k9dA-4n4rA:
undetectable		 5k9dA-4n4rA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 4n4r LPS-ASSEMBLY
LIPOPROTEIN LPTE
(Salmonella
enterica) 		3 / 3 ARG B 124
LYS B 150
ARG B  24
 None
 1.27A 6c06D-4n4rB:
undetectable		 6c06D-4n4rB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_2
(-)		 4n4r LPS-ASSEMBLY PROTEIN
LPTD
(Salmonella
enterica) 		4 / 5 GLN A 583
THR A 561
THR A 547
GLY A 606
 None
 1.21A 6gbnC-4n4rA:
undetectable		 6gbnC-4n4rA:
19.92