SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4n58'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_A_CCSA417_0
(ESTROGEN RECEPTOR)		 4n58 PECTOCIN M2
(Pectobacterium
carotovorum) 		3 / 3 GLU A  26
LYS A   2
VAL A  17
 None
 0.71A 1l2iA-4n58A:
undetectable		 1l2iA-4n58A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4n58 PECTOCIN M2
(Pectobacterium
carotovorum) 		4 / 8 ALA A 132
ASP A 150
ILE A 146
ILE A 259
 None
 0.93A 1p7lD-4n58A:
undetectable		 1p7lD-4n58A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4n58 PECTOCIN M2
(Pectobacterium
carotovorum) 		4 / 8 ALA A 132
ASP A 150
ILE A 146
ILE A 259
 None
 0.93A 1rg9D-4n58A:
undetectable		 1rg9D-4n58A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ6_A_SAMA300_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 4n58 PECTOCIN M2
(Pectobacterium
carotovorum) 		5 / 12 TYR A 195
ILE A 122
ILE A 199
ILE A 257
ASP A 150
 None
 0.95A 3uj6A-4n58A:
undetectable		 3uj6A-4n58A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD391_1
(TETX2 PROTEIN)		 4n58 PECTOCIN M2
(Pectobacterium
carotovorum) 		5 / 11 ARG A 183
MET A 201
ASN A 184
GLY A 152
ASN A 149
 None
None
None
None
SO4  A 308 (-3.9A)
 1.49A 4a99D-4n58A:
undetectable		 4a99D-4n58A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A207_1
(UNCHARACTERIZED
PROTEIN)		 4n58 PECTOCIN M2
(Pectobacterium
carotovorum) 		3 / 3 GLY A 219
GLU A 204
THR A 203
 None
 0.56A 4kouA-4n58A:
undetectable		 4kouA-4n58A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_A_FUAA1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4n58 PECTOCIN M2
(Pectobacterium
carotovorum) 		4 / 5 ILE A 177
LYS A 266
ILE A 265
VAL A 157
 None
None
SO4  A 307 ( 4.6A)
None
 1.02A 5jmnA-4n58A:
undetectable		 5jmnA-4n58A:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 4n58 PECTOCIN M2
(Pectobacterium
carotovorum) 		4 / 8 ALA A 132
ASP A 150
ILE A 146
ILE A 259
 None
 0.95A 5t8sA-4n58A:
undetectable		 5t8sA-4n58A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		 4n58 PECTOCIN M2
(Pectobacterium
carotovorum) 		4 / 7 LYS A 266
GLU A 218
LYS A 264
LEU A 263
 None
None
None
SO4  A 307 ( 4.4A)
 0.93A 6ci6A-4n58A:
undetectable		 6ci6A-4n58A:
14.11