SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4n5c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CET_A_CLQA1001_0
(PROTEIN (L-LACTATE
DEHYDROGENASE))		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		5 / 9 ASP A  21
ILE A  17
PHE A  38
ILE A  92
GLU A  91
 None
 1.17A 1cetA-4n5cA:
undetectable		 1cetA-4n5cA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HMY_A_SAMA328_0
(HAEIII
METHYLTRANSFERASE)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		4 / 8 PHE A 401
ASP A 360
ILE A 362
LEU A  29
 None
 0.92A 1hmyA-4n5cA:
undetectable		 1hmyA-4n5cA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_A_NIOA704_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		4 / 4 SER A 192
PHE A 188
GLU A 189
GLY A 185
 None
 1.44A 1icvA-4n5cA:
undetectable
1icvB-4n5cA:
undetectable		 1icvA-4n5cA:
14.25
1icvB-4n5cA:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_C_BEZC505_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		4 / 6 TYR A 145
ILE A  56
PRO A 428
GLU A 189
 None
 1.36A 1oniA-4n5cA:
undetectable
1oniC-4n5cA:
undetectable		 1oniA-4n5cA:
10.42
1oniC-4n5cA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9A_B_BEZB307_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 121
ILE A  99
TYR A 190
HIS A  52
GLN A  48
 None
 1.40A 1s9aB-4n5cA:
undetectable		 1s9aB-4n5cA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_2
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 100
HIS A 123
ILE A 127
 None
 0.42A 1s9pB-4n5cA:
undetectable		 1s9pB-4n5cA:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		4 / 7 TYR A 145
GLU A 149
HIS A  52
LEU A  51
 None
 1.04A 1tuvA-4n5cA:
undetectable		 1tuvA-4n5cA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		4 / 5 PHE A 245
PHE A 269
LEU A 273
PHE A 277
 None
 1.13A 2y69C-4n5cA:
undetectable
2y69J-4n5cA:
undetectable		 2y69C-4n5cA:
14.04
2y69J-4n5cA:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_P_CHDP1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		4 / 5 PHE A 245
PHE A 269
LEU A 273
PHE A 277
 None
 1.15A 2y69P-4n5cA:
undetectable
2y69W-4n5cA:
undetectable		 2y69P-4n5cA:
14.04
2y69W-4n5cA:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		4 / 6 PHE A 245
PHE A 269
LEU A 273
PHE A 277
 None
 1.06A 3ablP-4n5cA:
3.6
3ablW-4n5cA:
undetectable		 3ablP-4n5cA:
14.04
3ablW-4n5cA:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		4 / 5 PHE A 245
PHE A 269
LEU A 273
PHE A 277
 None
 1.17A 3abmC-4n5cA:
undetectable
3abmJ-4n5cA:
undetectable		 3abmC-4n5cA:
14.04
3abmJ-4n5cA:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		4 / 5 PHE A 245
PHE A 269
LEU A 273
PHE A 277
 None
 1.10A 3abmP-4n5cA:
3.6
3abmW-4n5cA:
undetectable		 3abmP-4n5cA:
14.04
3abmW-4n5cA:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		4 / 5 PHE A 245
PHE A 269
LEU A 273
PHE A 277
 None
 1.07A 3ag3C-4n5cA:
undetectable
3ag3J-4n5cA:
undetectable		 3ag3C-4n5cA:
14.04
3ag3J-4n5cA:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		4 / 7 PHE A 245
PHE A 269
LEU A 273
PHE A 277
 None
 1.06A 3asnP-4n5cA:
undetectable
3asnW-4n5cA:
undetectable		 3asnP-4n5cA:
14.04
3asnW-4n5cA:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		4 / 7 PHE A 245
PHE A 269
LEU A 273
PHE A 277
 None
 1.05A 3asoP-4n5cA:
3.6
3asoW-4n5cA:
undetectable		 3asoP-4n5cA:
14.04
3asoW-4n5cA:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXT_A_SAMA397_0
(PROBABLE
N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE
TRM1)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 198
ALA A 196
ARG A 199
ILE A 191
SER A 192
 None
 1.22A 3axtA-4n5cA:
undetectable		 3axtA-4n5cA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		3 / 3 GLU A 586
GLY A 589
THR A 590
 None
 0.55A 3iazA-4n5cA:
undetectable		 3iazA-4n5cA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3006_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		4 / 6 ASN A 339
MET A 313
GLU A 335
LYS A 333
 None
 1.23A 3kp6A-4n5cA:
undetectable
3kp6B-4n5cA:
undetectable		 3kp6A-4n5cA:
10.47
3kp6B-4n5cA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA801_0
(GLUTAMATE RECEPTOR 2)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 106
SER A 117
GLY A 105
ASN A 150
 None
 0.82A 3lslA-4n5cA:
undetectable
3lslD-4n5cA:
undetectable		 3lslA-4n5cA:
14.57
3lslD-4n5cA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID801_0
(GLUTAMATE RECEPTOR 2)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		4 / 8 ASN A 150
ILE A 106
SER A 117
GLY A 105
 None
 0.92A 3lslA-4n5cA:
undetectable
3lslD-4n5cA:
undetectable		 3lslA-4n5cA:
14.57
3lslD-4n5cA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		3 / 3 PHE A 370
SER A 336
GLN A 317
 None
 0.90A 3smtA-4n5cA:
undetectable		 3smtA-4n5cA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		4 / 6 PHE A 245
PHE A 269
LEU A 273
PHE A 277
 None
 1.03A 3wg7C-4n5cA:
3.6
3wg7J-4n5cA:
undetectable		 3wg7C-4n5cA:
14.04
3wg7J-4n5cA:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B53_B_ACTB1445_0
(IG GAMMA-4 CHAIN C
REGION)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		3 / 3 GLU A 189
GLY A 429
SER A 192
 None
 0.47A 4b53B-4n5cA:
undetectable		 4b53B-4n5cA:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_A_ASCA303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		4 / 7 PHE A 218
ILE A 179
TYR A 275
PHE A 188
 None
 1.29A 4o7gA-4n5cA:
4.0
4o7gB-4n5cA:
4.0		 4o7gA-4n5cA:
14.50
4o7gB-4n5cA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_B_ASCB304_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		4 / 6 PHE A 218
ILE A 179
TYR A 275
PHE A 188
 None
 1.42A 4o7gB-4n5cA:
4.0		 4o7gB-4n5cA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA603_1
(SERUM ALBUMIN)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		5 / 11 LEU A 398
SER A 369
LEU A 372
LEU A 435
LEU A 442
 None
 1.21A 4or0A-4n5cA:
undetectable		 4or0A-4n5cA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_B_NPSB603_1
(SERUM ALBUMIN)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		5 / 11 ARG A 505
VAL A 538
SER A 537
LEU A 812
LEU A 532
 None
 1.21A 4or0B-4n5cA:
2.3		 4or0B-4n5cA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTH_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		3 / 3 ASP A  42
LEU A  41
PHE A  38
 None
 0.63A 4pthA-4n5cA:
undetectable		 4pthA-4n5cA:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_A_DESA601_1
(ESTROGEN RECEPTOR)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 771
GLU A 770
LEU A 705
LEU A 702
ARG A 813
 None
 1.16A 4zn7A-4n5cA:
undetectable		 4zn7A-4n5cA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		4 / 6 PHE A 245
PHE A 269
LEU A 273
PHE A 277
 None
 1.07A 5b1bC-4n5cA:
3.6
5b1bJ-4n5cA:
undetectable		 5b1bC-4n5cA:
14.04
5b1bJ-4n5cA:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		5 / 10 ALA A 771
GLU A 770
LEU A 702
ARG A 813
LEU A 761
 None
 1.39A 5dxbA-4n5cA:
undetectable		 5dxbA-4n5cA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HYR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		5 / 10 ALA A 771
GLU A 770
LEU A 702
ARG A 813
LEU A 761
 None
 1.37A 5hyrA-4n5cA:
undetectable		 5hyrA-4n5cA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_0
(REGULATORY PROTEIN
TETR)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A  95
ILE A  99
TYR A 190
ASP A  42
PHE A  34
 None
 1.44A 5vlmA-4n5cA:
1.9		 5vlmA-4n5cA:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		4 / 5 PHE A 245
PHE A 269
LEU A 273
PHE A 277
 None
 1.07A 5wauC-4n5cA:
undetectable
5wauJ-4n5cA:
undetectable		 5wauC-4n5cA:
14.04
5wauJ-4n5cA:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		4 / 5 PHE A 245
PHE A 269
LEU A 273
PHE A 277
 None
 1.12A 5wauc-4n5cA:
undetectable
5wauj-4n5cA:
undetectable		 5wauc-4n5cA:
14.04
5wauj-4n5cA:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		5 / 9 ALA A 771
GLU A 770
LEU A 702
ARG A 813
LEU A 761
 None
 1.40A 5wgqA-4n5cA:
undetectable		 5wgqA-4n5cA:
7.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		4 / 5 PHE A 245
PHE A 269
LEU A 273
PHE A 277
 None
 1.08A 5xdqC-4n5cA:
undetectable
5xdqJ-4n5cA:
undetectable		 5xdqC-4n5cA:
14.04
5xdqJ-4n5cA:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		4 / 5 PHE A 245
PHE A 269
LEU A 273
PHE A 277
 None
 1.11A 5xdqP-4n5cA:
undetectable
5xdqW-4n5cA:
undetectable		 5xdqP-4n5cA:
14.04
5xdqW-4n5cA:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		4 / 6 PHE A 245
PHE A 269
LEU A 273
PHE A 277
 None
 1.09A 5z86C-4n5cA:
3.7
5z86J-4n5cA:
undetectable		 5z86C-4n5cA:
14.04
5z86J-4n5cA:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		4 / 6 PHE A 245
PHE A 269
LEU A 273
PHE A 277
 None
 1.11A 5zcpC-4n5cA:
3.7
5zcpJ-4n5cA:
undetectable		 5zcpC-4n5cA:
14.04
5zcpJ-4n5cA:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_2
(CARBONIC ANHYDRASE 2)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		4 / 5 HIS A 128
GLU A 149
LEU A  41
VAL A  44
 None
 1.14A 6bc9A-4n5cA:
undetectable		 6bc9A-4n5cA:
8.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_B_ACTB804_0
(UNCHARACTERIZED
PROTEIN)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 530
VAL A 552
LEU A 576
ALA A 533
 None
 1.22A 6d8pB-4n5cA:
undetectable		 6d8pB-4n5cA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		5 / 12 TYR A 190
LEU A 193
SER A 432
ILE A  56
LEU A 187
 None
 1.39A 6djzB-4n5cA:
undetectable		 6djzB-4n5cA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRX_A_H8GA1201_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 121
VAL A 157
SER A 158
PHE A 168
VAL A 167
 None
 1.46A 6drxA-4n5cA:
undetectable		 6drxA-4n5cA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 4n5c CARGO-TRANSPORT
PROTEIN YPP1
(Saccharomyces
cerevisiae) 		4 / 8 ASN A 347
GLN A 274
ILE A 306
GLU A 307
 None
 1.07A 6hzpA-4n5cA:
undetectable		 6hzpA-4n5cA:
20.60