SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4n5f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_A_ZMRA466_1
(NEURAMINIDASE)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
5 / 12 ARG A  17
GLU A  75
ALA A 289
ARG A 296
ASN A 293
None
1.44A 1a4gA-4n5fA:
undetectable
1a4gA-4n5fA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_1
(NEURAMINIDASE)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
5 / 12 ARG A  17
GLU A  75
ALA A 289
ARG A 296
ASN A 293
None
1.45A 1a4gB-4n5fA:
undetectable
1a4gB-4n5fA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
4 / 6 GLY A  96
PRO A  97
ILE A 234
GLY A 100
None
0.79A 1usqB-4n5fA:
undetectable
1usqB-4n5fA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
4 / 6 GLY A  96
PRO A  97
ILE A 234
GLY A 100
None
0.79A 1usqC-4n5fA:
undetectable
1usqC-4n5fA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
4 / 6 GLY A  96
PRO A  97
ILE A 234
GLY A 100
None
0.79A 1usqD-4n5fA:
undetectable
1usqD-4n5fA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
4 / 6 GLY A  96
PRO A  97
ILE A 234
GLY A 100
None
0.82A 1usqE-4n5fA:
undetectable
1usqE-4n5fA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_2
(DIPEPTIDYL PEPTIDASE
IV)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
3 / 3 ARG A 296
SER A  62
TYR A  63
None
0.70A 1x70A-4n5fA:
undetectable
1x70A-4n5fA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_E_REAE504_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
5 / 11 ILE A 244
ALA A 316
ALA A 319
GLN A 318
LEU A 298
None
1.09A 2aclE-4n5fA:
undetectable
2aclE-4n5fA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B7Z_B_MK1B200_2
(HIV-1 PROTEASE)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
5 / 12 GLY A 152
GLY A 192
ILE A 194
ALA A 166
VAL A 168
None
1.00A 2b7zB-4n5fA:
undetectable
2b7zB-4n5fA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2477_1
(NEURAMINIDASE)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
5 / 12 ARG A  17
GLU A  75
ALA A 289
ARG A 296
ASN A 293
None
1.46A 2cmlB-4n5fA:
undetectable
2cmlB-4n5fA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3477_1
(NEURAMINIDASE)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
5 / 12 ARG A  17
GLU A  75
ALA A 289
ARG A 296
ASN A 293
None
1.43A 2cmlC-4n5fA:
undetectable
2cmlC-4n5fA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H4J_A_NCAA1002_0
(NAD-DEPENDENT
DEACETYLASE)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
4 / 5 ALA A  77
ILE A 253
ILE A 204
ASP A 355
None
1.05A 2h4jA-4n5fA:
undetectable
2h4jA-4n5fA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
4 / 6 GLY A  96
PRO A  97
ILE A 234
GLY A 100
None
0.84A 2jkjA-4n5fA:
undetectable
2jkjA-4n5fA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
4 / 6 GLY A  96
PRO A  97
ILE A 234
GLY A 100
None
0.83A 2jkjB-4n5fA:
undetectable
2jkjB-4n5fA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
4 / 6 GLY A  96
PRO A  97
ILE A 234
GLY A 100
None
0.83A 2jkjC-4n5fA:
undetectable
2jkjC-4n5fA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
4 / 6 GLY A  96
PRO A  97
ILE A 234
GLY A 100
None
0.78A 2jklB-4n5fA:
undetectable
2jklB-4n5fA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_4
(PROTEASE RETROPEPSIN)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
3 / 3 ASP A 222
THR A 190
PRO A 191
None
0.54A 2q64B-4n5fA:
undetectable
2q64B-4n5fA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
4 / 5 ILE A 120
HIS A  90
ARG A 118
GLY A  46
None
1.23A 3b9mA-4n5fA:
2.3
3b9mA-4n5fA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
5 / 12 GLY A 241
ASN A 238
ILE A  54
GLY A 121
ALA A 122
None
1.02A 3hs6B-4n5fA:
undetectable
3hs6B-4n5fA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_B_BEZB264_0
(ECHA1_1)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
4 / 7 ILE A 292
LEU A 251
ALA A  78
ALA A  77
None
0.88A 3r9tB-4n5fA:
undetectable
3r9tB-4n5fA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SAN_A_ZMRA901_1
(NEURAMINIDASE)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
5 / 12 ARG A  17
GLU A  75
ALA A 289
ARG A 296
ASN A 293
None
1.44A 3sanA-4n5fA:
undetectable
3sanA-4n5fA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SAN_B_ZMRB901_1
(NEURAMINIDASE)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
5 / 12 ARG A  17
GLU A  75
ALA A 289
ARG A 296
ASN A 293
None
1.49A 3sanB-4n5fA:
undetectable
3sanB-4n5fA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUG_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
5 / 12 GLY A 102
ARG A 118
GLY A  96
ALA A 115
ASP A 113
None
1.02A 3sugA-4n5fA:
undetectable
3sugA-4n5fA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_A_ZMRA1002_1
(NEURAMINIDASE)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
5 / 12 ARG A  17
GLU A  75
ALA A 289
ARG A 296
ASN A 293
None
1.45A 3ticA-4n5fA:
undetectable
3ticA-4n5fA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_B_ZMRB1002_1
(NEURAMINIDASE)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
5 / 12 ARG A  17
GLU A  75
ALA A 289
ARG A 296
ASN A 293
None
1.47A 3ticB-4n5fA:
undetectable
3ticB-4n5fA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_C_ZMRC1002_1
(NEURAMINIDASE)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
5 / 12 ARG A  17
GLU A  75
ALA A 289
ARG A 296
ASN A 293
None
1.45A 3ticC-4n5fA:
undetectable
3ticC-4n5fA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_D_ZMRD1002_1
(NEURAMINIDASE)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
5 / 12 ARG A  17
GLU A  75
ALA A 289
ARG A 296
ASN A 293
None
1.46A 3ticD-4n5fA:
undetectable
3ticD-4n5fA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_3
(PROTEASE)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
3 / 3 ASP A 222
THR A 190
PRO A 191
None
0.55A 3tkgD-4n5fA:
undetectable
3tkgD-4n5fA:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPN_A_ZMRA700_1
(NEURAMINIDASE)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
5 / 12 ARG A  17
ASP A 259
ALA A 289
ARG A 296
ASN A 293
None
1.22A 4cpnA-4n5fA:
undetectable
4cpnA-4n5fA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPN_A_ZMRA700_1
(NEURAMINIDASE)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
5 / 12 ARG A  17
GLU A  75
ALA A 289
ARG A 296
ASN A 293
None
1.48A 4cpnA-4n5fA:
undetectable
4cpnA-4n5fA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_A_ZMRA1471_1
(NEURAMINIDASE)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
5 / 12 ARG A  17
GLU A  75
ALA A 289
ARG A 296
ASN A 293
None
1.45A 4cpzA-4n5fA:
undetectable
4cpzA-4n5fA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_B_ZMRB1471_1
(NEURAMINIDASE)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
5 / 12 ARG A  17
GLU A  75
ALA A 289
ARG A 296
ASN A 293
None
1.43A 4cpzB-4n5fA:
undetectable
4cpzB-4n5fA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_1
(NEURAMINIDASE)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
5 / 12 ARG A  17
ASP A 259
ALA A 289
ARG A 296
ASN A 293
None
1.20A 4cpzC-4n5fA:
undetectable
4cpzC-4n5fA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_1
(NEURAMINIDASE)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
5 / 12 ARG A  17
GLU A  75
ALA A 289
ARG A 296
ASN A 293
None
1.44A 4cpzC-4n5fA:
undetectable
4cpzC-4n5fA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_D_ZMRD1471_1
(NEURAMINIDASE)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
5 / 12 ARG A  17
GLU A  75
ALA A 289
ARG A 296
ASN A 293
None
1.40A 4cpzD-4n5fA:
undetectable
4cpzD-4n5fA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_1
(NEURAMINIDASE)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
5 / 12 ARG A  17
GLU A  75
ALA A 289
ARG A 296
ASN A 293
None
1.41A 4cpzF-4n5fA:
undetectable
4cpzF-4n5fA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_1
(NEURAMINIDASE)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
5 / 12 ARG A  17
ASP A 259
ALA A 289
ARG A 296
ASN A 293
None
1.14A 4cpzG-4n5fA:
undetectable
4cpzG-4n5fA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_1
(NEURAMINIDASE)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
5 / 12 ARG A  17
GLU A  75
ALA A 289
ARG A 296
ASN A 293
None
1.41A 4cpzG-4n5fA:
undetectable
4cpzG-4n5fA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_1
(NEURAMINIDASE)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
5 / 12 ARG A  17
ASP A 259
ALA A 289
ARG A 296
ASN A 293
None
1.14A 4cpzH-4n5fA:
undetectable
4cpzH-4n5fA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_1
(NEURAMINIDASE)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
5 / 12 ARG A  17
GLU A  75
ALA A 289
ARG A 296
ASN A 293
None
1.41A 4cpzH-4n5fA:
undetectable
4cpzH-4n5fA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
4 / 5 TYR A  66
GLY A 245
GLU A 240
VAL A 372
None
1.11A 4nkvD-4n5fA:
undetectable
4nkvD-4n5fA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W9N_C_CCSC1548_0
(ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
3 / 3 ALA A 141
TRP A 148
VAL A 149
None
0.32A 4w9nC-4n5fA:
undetectable
4w9nC-4n5fA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WA5_A_ZMRA501_1
(NEURAMINIDASE)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
5 / 12 ARG A  17
ASP A 259
ALA A 289
ARG A 296
ASN A 293
None
1.27A 4wa5A-4n5fA:
undetectable
4wa5A-4n5fA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WA5_A_ZMRA501_1
(NEURAMINIDASE)
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia)
5 / 12 ARG A  17
GLU A  75
ALA A 289
ARG A 296
ASN A 293
None
1.42A 4wa5A-4n5fA:
undetectable
4wa5A-4n5fA:
20.99