SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4n5u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4n5u RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE F
(Homo
sapiens) 		3 / 3 GLN A 603
THR A 688
ASN A 636
 None
 0.72A 3v4tE-4n5uA:
undetectable		 3v4tE-4n5uA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0I_B_TA1B502_1
(TUBULIN BETA CHAIN)		 4n5u RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE F
(Homo
sapiens) 		5 / 12 VAL A 613
LEU A 674
SER A 696
ARG A 702
LEU A 700
 None
 1.04A 6b0iB-4n5uA:
undetectable		 6b0iB-4n5uA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0L_B_TA1B502_1
(TUBULIN BETA CHAIN)		 4n5u RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE F
(Homo
sapiens) 		5 / 12 VAL A 613
LEU A 674
SER A 696
ARG A 702
LEU A 700
 None
 1.15A 6b0lB-4n5uA:
undetectable		 6b0lB-4n5uA:
18.52