SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4n6c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA154_1
(CALMODULIN)		 4n6c UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		4 / 7 MET A 116
GLU A  62
LEU A 120
GLU A 124
 None
 1.13A 1linA-4n6cA:
undetectable		 1linA-4n6cA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)		 4n6c UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 PHE A 148
TRP A 133
GLU A  62
 None
 1.12A 1mogA-4n6cA:
undetectable		 1mogA-4n6cA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_A_BEZA352_0
(D-AMINO-ACID OXIDASE)		 4n6c UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		4 / 6 LEU A 106
TYR A  21
ILE A 110
GLY A 158
 None
 0.92A 2du8A-4n6cA:
undetectable		 2du8A-4n6cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_B_BEZB1352_0
(D-AMINO-ACID OXIDASE)		 4n6c UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		4 / 6 LEU A 106
TYR A  21
ILE A 110
GLY A 158
 None
 0.94A 2du8B-4n6cA:
undetectable		 2du8B-4n6cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V35_A_NTIA317_1
(ALDOSE REDUCTASE)		 4n6c UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		4 / 8 TRP A  54
HIS A  -3
PRO A  74
TRP A  80
 None
 1.43A 3v35A-4n6cA:
undetectable		 3v35A-4n6cA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 4n6c UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		4 / 8 LEU A  57
VAL A  71
TRP A  89
LEU A  86
 None
 0.95A 3v81A-4n6cA:
undetectable		 3v81A-4n6cA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y80_A_IREA402_0
(CYCLIN-G-ASSOCIATED
KINASE)		 4n6c UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 11 VAL A 145
ILE A 149
ASN A 152
THR A 153
ILE A 117
 None
 1.23A 5y80A-4n6cA:
undetectable		 5y80A-4n6cA:
18.13