SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4n6r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB6_0
(GRAMICIDIN A)		 4n6r VELB
(Aspergillus
nidulans) 		3 / 3 TRP B 259
ALA B 246
VAL B 261
 None
 0.97A 1bdwA-4n6rB:
undetectable
1bdwB-4n6rB:
undetectable		 1bdwA-4n6rB:
3.46
1bdwB-4n6rB:
3.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 4n6r VELB
(Aspergillus
nidulans) 		4 / 8 VAL B 258
GLY B 257
VAL B  64
ILE B  89
 None
 0.79A 2a1mB-4n6rB:
undetectable		 2a1mB-4n6rB:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_A_NCAA900_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 4n6r VELB
(Aspergillus
nidulans) 		4 / 5 ILE B  83
PHE B 322
PHE B 317
ILE B 326
 None
 1.05A 2hjhA-4n6rB:
undetectable		 2hjhA-4n6rB:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA701_0
(FERROCHELATASE)		 4n6r VELB
(Aspergillus
nidulans) 		4 / 8 LEU B  91
PRO B 304
VAL B 282
GLY B 283
 None
 1.12A 2qd5A-4n6rB:
undetectable		 2qd5A-4n6rB:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 4n6r VELB
(Aspergillus
nidulans) 		4 / 5 VAL B 282
GLY B 283
TYR B 112
ASP B 108
 None
 1.08A 3w9tA-4n6rB:
undetectable		 3w9tA-4n6rB:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 4n6r VELB
(Aspergillus
nidulans) 		4 / 5 VAL B 282
GLY B 283
TYR B 112
ASP B 108
 None
 1.08A 3w9tB-4n6rB:
undetectable		 3w9tB-4n6rB:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 4n6r VELB
(Aspergillus
nidulans) 		4 / 5 VAL B 282
GLY B 283
TYR B 112
ASP B 108
 None
 1.09A 3w9tC-4n6rB:
undetectable		 3w9tC-4n6rB:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 4n6r VELB
(Aspergillus
nidulans) 		4 / 5 VAL B 282
GLY B 283
TYR B 112
ASP B 108
 None
 1.08A 3w9tD-4n6rB:
undetectable		 3w9tD-4n6rB:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 4n6r VELB
(Aspergillus
nidulans) 		4 / 5 VAL B 282
GLY B 283
TYR B 112
ASP B 108
 None
 1.08A 3w9tE-4n6rB:
undetectable		 3w9tE-4n6rB:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 4n6r VELB
(Aspergillus
nidulans) 		4 / 5 VAL B 282
GLY B 283
TYR B 112
ASP B 108
 None
 1.08A 3w9tF-4n6rB:
undetectable		 3w9tF-4n6rB:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 4n6r VELB
(Aspergillus
nidulans) 		4 / 5 VAL B 282
GLY B 283
TYR B 112
ASP B 108
 None
 1.08A 3w9tG-4n6rB:
undetectable		 3w9tG-4n6rB:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 4n6r VELB
(Aspergillus
nidulans) 		5 / 12 ILE B  68
THR B  84
VAL B 114
SER B 266
VAL B 267
 None
 1.38A 6bzoC-4n6rB:
undetectable		 6bzoC-4n6rB:
15.24