SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4n6s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4n6s C-PHYCOCYANIN BETA
SUBUNIT
(Thermosynechococ
cus
vulcanus) 		3 / 3 SER B  46
ASP B  39
CYH B 155
 None
CYC  B 202 (-3.0A)
CYC  B 202 (-1.8A)
 1.12A 2br4E-4n6sB:
undetectable		 2br4E-4n6sB:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4n6s C-PHYCOCYANIN BETA
SUBUNIT
(Thermosynechococ
cus
vulcanus) 		5 / 12 ILE B 162
GLY B 164
ASP B 167
ILE B 133
LEU B 107
 None
 1.03A 4a81A-4n6sB:
undetectable		 4a81A-4n6sB:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_2
(TUBULIN BETA-2B
CHAIN)		 4n6s C-PHYCOCYANIN BETA
SUBUNIT
(Thermosynechococ
cus
vulcanus) 		5 / 12 LEU B 107
ALA B 169
ILE B  99
ALA B  98
ILE B  44
 None
 0.97A 4o2bD-4n6sB:
undetectable		 4o2bD-4n6sB:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_2
(TUBULIN BETA CHAIN)		 4n6s C-PHYCOCYANIN BETA
SUBUNIT
(Thermosynechococ
cus
vulcanus) 		5 / 12 LEU B 107
ALA B 169
ILE B  99
ALA B  98
ILE B  44
 None
 1.00A 5eypB-4n6sB:
undetectable		 5eypB-4n6sB:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 4n6s C-PHYCOCYANIN BETA
SUBUNIT
(Thermosynechococ
cus
vulcanus) 		3 / 3 ALA B  26
ASN B  29
LEU B  30
 None
 0.25A 5i1nB-4n6sB:
undetectable		 5i1nB-4n6sB:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 4n6s C-PHYCOCYANIN BETA
SUBUNIT
(Thermosynechococ
cus
vulcanus) 		3 / 3 ALA B  26
ASN B  29
LEU B  30
 None
 0.34A 5i1oC-4n6sB:
undetectable		 5i1oC-4n6sB:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 4n6s C-PHYCOCYANIN BETA
SUBUNIT
(Thermosynechococ
cus
vulcanus) 		3 / 3 ALA B  26
ASN B  29
LEU B  30
 None
 0.26A 5i1pA-4n6sB:
undetectable		 5i1pA-4n6sB:
13.04